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Celastrol as an intestinal FXR inhibitor triggers tripolide-induced intestinal bleeding: Underlying mechanism of gastrointestinal injury induced by Tripterygium wilfordii 期刊论文
PHYTOMEDICINE, 2023, 卷号: 121, 页码: 155054
作者:  Dai,Manyun;  Peng,Wan;  Lin,Lisha;  Wu,Zhanxuan;  Zhang,Ting;  Zhao,Qi;  Cheng,Yan;  Lin,Qiuxia;  Zhang,Binbin;  Liu,Aiming;  Rao,Qianru;  Huang,Jianfeng;  Zhao,Jinhua;  Gonzalez,Frank J.;  Li,Fei
浏览  |  Adobe PDF(17974Kb)  |  收藏  |  浏览/下载:68/19  |  提交时间:2024/07/17
Intestinal bleeding  Triptolide  Celastrol  Intestinal FXR  Tripterygium wilfordii  FARNESOID-X-RECEPTOR  BACTERIAL TRANSLOCATION  ACTIVATION  INFLAMMATION  DYSFUNCTION  TRIPTOLIDE  MICROBIOTA  PREVENTS  OBESITY  MICE  
Five distinct fucan sulfates from sea cucumber Pattalus mollis: Purification, structural characterization and anticoagulant activities 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 卷号: 186, 页码: 535-543
作者:  Ma,Yan;  Gao,Na;  Zuo,Zhichuang;  Li,Shanni;  Zheng,Wenqi;  Shi,Xiang;  Liu,Qipei;  Ma,Ting;  Yin,Ronghua;  Li,Xian;  Zhao,Jinhua
收藏  |  浏览/下载:133/0  |  提交时间:2022/04/02
Sea cucumber  Fucan sulfate  Chemical structure  Anticoagulant  Pattalus mollis  FUCOSYLATED GLYCOSAMINOGLYCAN  REPEATING UNIT  FUCOIDAN  POLYSACCHARIDES  ELUCIDATION  OLIGOSACCHARIDES  SPECTROSCOPY  
Pharmacokinetics and Pharmacodynamics of a Depolymerized Glycosaminoglycan from Holothuria fuscopunctata, a Novel Anticoagulant Candidate, in Rats by Bioanalytical Methods 期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 4, 页码: 212
作者:  Liu,Shuang;  Zhang,Taocui;  Sun,Huifang;  Lin,Lisha;  Gao,Na;  Wang,Weili;  Li,Sujuan;  Zhao,Jinhua
浏览  |  Adobe PDF(1230Kb)  |  收藏  |  浏览/下载:258/61  |  提交时间:2022/04/02
pharmacokinetics  pharmacodynamics  anticoagulant  fucosylated glycosaminoglycan  dHG-5  method validation  
Unveiling the Disaccharide-Branched Glycosaminoglycan and Anticoagulant Potential of Its Derivatives 期刊论文
BIOMACROMOLECULES, 2021, 卷号: 22, 期号: 3, 页码: 1244-1255
作者:  Yin,Ronghua;  Zhou,Lutan;  Gao,Na;  Lin,Lisha;  Sun,Huifang;  Chen,Dingyuan;  Cai,Ying;  Zuo,Zhili;  Hu,Kaifeng;  Huang,Shengxiong;  Liu,Jikai;  Zhao,Jinhua
浏览  |  Adobe PDF(4401Kb)  |  收藏  |  浏览/下载:148/33  |  提交时间:2022/04/02
FUCOSYLATED CHONDROITIN SULFATE  DEPOLYMERIZED HOLOTHURIAN GLYCOSAMINOGLYCAN  INTRINSIC TENASE COMPLEX  SEA-CUCUMBER  FUCOSE BRANCHES  BODY-WALL  INDEPENDENT INHIBITION  POLYSACCHARIDE ACCOUNT  FACTOR XASE  HEPARIN  
A regular fucan sulfate from Stichopus herrmanni and its peroxide depolymerization: Structure and anticoagulant activity 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 256, 页码: 117513
作者:  Li,Xiaomei;  Li,Shanni;  Liu,Jie;  Lin,Lisha;  Sun,Huifang;  Yang,Wenjiao;  Cai,Ying;  Gao,Na;  Zhou,Lutan;  Qin,Hongbo;  Yin,Ronghua;  Zhao,Jinhua
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fucan sulfate  peroxide depolymerization  oligosaccharides  anti-thrombin activity  FUCOSYLATED CHONDROITIN SULFATE  FREE-RADICAL DEPOLYMERIZATION  PHYSICOCHEMICAL CHARACTERISTICS  REPEATING UNIT  BODY-WALL  SEA  FUCOIDAN  GLYCOSAMINOGLYCAN  POLYSACCHARIDES  HEPARIN  
Characterization of the Hydrolysis Kinetics of Fucosylated Glycosaminoglycan in Mild Acid and Structures of the Resulting Oligosaccharides 期刊论文
MARINE DRUGS, 2020
作者:  Liu, Xixi;  Zhang, Zhexian;  Mao, Hui;  Wang, Pin;  Zuo, Zhichuang;  Gao, Li;  Shi, Xiang;  Yin, Ronghua;  Gao, Na;  Zhao, Jinhua
浏览  |  Adobe PDF(1321Kb)  |  收藏  |  浏览/下载:201/65  |  提交时间:2021/01/05
(-)-Epigallocatechin-3-gallate (EGCG) attenuates salt-induced hypertension and renal injury in Dahl salt-sensitive rats 期刊论文
SCIENTIFIC REPORTS, 2020
作者:  Luo, Dan;  Xu, Jianping;  Chen, Xuejiao;  Zhu, Xu;  Liu, Shuang;  Li, Jie;  Xu, Xinting;  Ma, Xiao;  Zhao, Jinhua;  Ji, Xu
浏览  |  Adobe PDF(5428Kb)  |  收藏  |  浏览/下载:166/31  |  提交时间:2021/01/05
Pu-Erh Tea Relaxes the Thoracic Aorta of Rats by Reducing Intracellular Calcium 期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 13
作者:  Luo, Dan;  Chen, Xuejiao;  Zhu, Xu;  Liu, Shuang;  Li, Jie;  Xu, Jianping;  Zhao, Jinhua;  Ji, Xu
浏览  |  Adobe PDF(4082Kb)  |  收藏  |  浏览/下载:475/55  |  提交时间:2020/03/18
endothelium-independent vasodilation  hypertension  pu-erh tea  tea components  theabrownins  
Precise structures and anti-intrinsic tenase complex activity of three fucosylated glycosaminoglycans and their fragments 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 224, 页码: 10
作者:  Cai, Ying;  Yang, Wenjiao;  Li, Xiaomei;  Zhou, Lutan;  Wang, Zhongjuan;  Lin, Lisha;  Chen, Dingyuan;  Zhao, Longyan;  Li, Zhongkun;  Liu, Shubai;  Yin, Ronghua;  Zuo, Zhili;  Gao, Na;  Zhao, Jinhua
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Fucosylated glycosaminoglycan  Oligosaccharide  Chemical structure  iXase  
Precise Structure and Anticoagulant Activity of Fucosylated Glycosaminoglycan from Apostichopus japonicus: Analysis of Its Depolymerized Fragments 期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 4, 页码: 13
作者:  Guan, Ruowei;  Peng, Yuan;  Zhou, Lutan;  Zheng, Wenqi;  Liu, Xixi;  Wang, Pin;  Yuan, Qingxia;  Gao, Na;  Zhao, Longyan;  Zhao, Jinhua
浏览  |  Adobe PDF(2313Kb)  |  收藏  |  浏览/下载:209/12  |  提交时间:2019/06/24
Apostichopus japonicus  fucosylated glycosaminoglycan  oligosaccharide  unambiguous structure  anti-Fxase