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Dual roles of fucoidan-GPIbα interaction in thrombosis and hemostasis: implications for drug development targeting GPIbα 期刊论文
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2023, 卷号: 21, 期号: 5, 页码: 1274-1288
Authors:  Shen,Chuanbin;  Mackeigan,Daniel T.;  Shoara,Aron A.;  Xu,Runjia;  Bhoria,Preeti;  Karakas,Danielle;  Ma,Wenjing;  Cerenzia,Eric;  Chen,ZiYan;  Hoard,Brock;  Lin,Lisha;  Lei,Xi;  Zhu,Guangheng;  Chen,Pingguo;  Johnson,Philip E.;  Ni,Heyu
View  |  Adobe PDF(4055Kb)  |  Favorite  |  View/Download：12/2  |  Submit date：2024/07/22
fucoidan  glycoprotein Ib  platelet  thrombosis  von Willebrand factor  VON-WILLEBRAND-FACTOR  PLATELET GLYCOPROTEIN IB  MOLECULAR-WEIGHT FUCOIDAN  ARTERIAL THROMBOSIS  IX  AGGREGATION  RECEPTOR  ACTIVATION  FIBRINOGEN  INTEGRIN  
Five distinct fucan sulfates from sea cucumber Pattalus mollis: Purification, structural characterization and anticoagulant activities 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 卷号: 186, 页码: 535-543
Authors:  Ma,Yan;  Gao,Na;  Zuo,Zhichuang;  Li,Shanni;  Zheng,Wenqi;  Shi,Xiang;  Liu,Qipei;  Ma,Ting;  Yin,Ronghua;  Li,Xian;  Zhao,Jinhua
Favorite  |  View/Download：112/0  |  Submit date：2022/04/02
Sea cucumber  Fucan sulfate  Chemical structure  Anticoagulant  Pattalus mollis  FUCOSYLATED GLYCOSAMINOGLYCAN  REPEATING UNIT  FUCOIDAN  POLYSACCHARIDES  ELUCIDATION  OLIGOSACCHARIDES  SPECTROSCOPY  
Structural characterization and anticoagulant analysis of the novel branched fucosylated glycosaminoglycan from sea cucumber Holothuria nobilis 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 269, 页码: 118290
Authors:  Li,Shanni;  Zhong,Wei;  Pan,Ying;  Lin,Lisha;  Cai,Ying;  Mao,Hui;  Zhang,Taocui;  Li,Sujuan;  Chen,Ru;  Zhou,Lutan;  Wang,Weili;  Cui,Qinghua;  Yin,Ronghua;  Huang,Shengxiong;  Zhao,Jinhua
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Disaccharide branch  Fucosylated glycosaminoglycan  Holothuria nobilis  Oligosaccharide  Anticoagulant  INTRINSIC TENASE COMPLEX  CHONDROITIN SULFATE  ACAUDINA-MOLPADIOIDEA  FACTOR XASE  HEPARIN  DEPOLYMERIZATION  OLIGOSACCHARIDES  POLYSACCHARIDES  DERIVATIVES  
Pharmacokinetics and Pharmacodynamics of a Depolymerized Glycosaminoglycan from Holothuria fuscopunctata, a Novel Anticoagulant Candidate, in Rats by Bioanalytical Methods 期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 4, 页码: 212
Authors:  Liu,Shuang;  Zhang,Taocui;  Sun,Huifang;  Lin,Lisha;  Gao,Na;  Wang,Weili;  Li,Sujuan;  Zhao,Jinhua
Adobe PDF(1230Kb)  |  Favorite  |  View/Download：215/58  |  Submit date：2022/04/02
pharmacokinetics  pharmacodynamics  anticoagulant  fucosylated glycosaminoglycan  dHG-5  method validation  
High-molecular-weight fucosylated glycosaminoglycan induces human platelet aggregation depending on alpha(IIb)beta(3) and platelet secretion 期刊论文
PLATELETS, 2021, 卷号: 32, 期号: 7, 页码: 975-983
Authors:  Lin,Lisha;  Yang,Lian;  Chen,Jun;  Zhou,Lutan;  Li,Sujuan;  Gao,Na;  Zhao,Jinhua
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Aggregation  fucosylated glycosaminoglycan  human platelets  secretion  alpha(IIb beta 3)  DEPOLYMERIZED HOLOTHURIAN GLYCOSAMINOGLYCAN  INTRINSIC TENASE COMPLEX  INTEGRIN ALPHA(IIB)BETA(3)  ACTIVATION  AGGLUTINATION  RECEPTOR  ADP  INHIBITION  GENERATION  MECHANISM  
A regular fucan sulfate from Stichopus herrmanni and its peroxide depolymerization: Structure and anticoagulant activity 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 256, 页码: 117513
Authors:  Li,Xiaomei;  Li,Shanni;  Liu,Jie;  Lin,Lisha;  Sun,Huifang;  Yang,Wenjiao;  Cai,Ying;  Gao,Na;  Zhou,Lutan;  Qin,Hongbo;  Yin,Ronghua;  Zhao,Jinhua
View  |  Adobe PDF(3183Kb)  |  Favorite  |  View/Download：114/20  |  Submit date：2022/04/02
fucan sulfate  peroxide depolymerization  oligosaccharides  anti-thrombin activity  FUCOSYLATED CHONDROITIN SULFATE  FREE-RADICAL DEPOLYMERIZATION  PHYSICOCHEMICAL CHARACTERISTICS  REPEATING UNIT  BODY-WALL  SEA  FUCOIDAN  GLYCOSAMINOGLYCAN  POLYSACCHARIDES  HEPARIN  
海地瓜（Acaudina molpadioides）酸性多糖 化学结构与抗凝活性研究 学位论文
, 2020
Authors:  毛慧
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High-molecular-weight fucosylated glycosaminoglycan induces human platelet aggregation depending on alpha(IIb)beta(3) and platelet secretion 期刊论文
PLATELETS, 2020
Authors:  Lin, Lisha;  Yang, Lian;  Chen, Jun;  Zhou, Lutan;  Li, Sujuan;  Gao, Na;  Zhao, Jinhua
View  |  Adobe PDF(4004Kb)  |  Favorite  |  View/Download：113/22  |  Submit date：2021/01/05
Purification, structural characterization and anticoagulant activities of four sulfated polysaccharides from sea cucumber Holothuria fuscopunctata 期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020
Authors:  Gao, Na;  Chen, Ru;  Mou, Rongrong;  Xiang, Jingying;  Zhou, Kai;  Li, Zi;  Zhao, Jinhua
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dFG-53 的基础药代动力学特征及其 PK/PD 相关性分析 学位论文
, 2019
Authors:  刘爽
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