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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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昆明植物所硕博研究生... [1]
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赵金华 [5]
罗晓东 [1]
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纪旭 [1]
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Oligosaccharide Blocks PAR1 (Proteinase-Activated Receptor 1)-PAR4-Mediated Platelet Activation by Binding to Thrombin Exosite II and Impairs Thrombosis
期刊论文
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2023, 卷号: 43, 期号: 2, 页码: 253-266
Authors:
Li,Sujuan
;
Wang,Weili
;
Lin,Lisha
;
Yang,Lian
;
Cai,Ying
;
Yang,Xingzhi
;
Zhang,Taocui
;
Xiao,Chuang
;
Yan,Hui
;
Gao,Na
;
Zhao,Jinhua
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Submit date:2024/05/09
oligosaccharide
platelet activation
receptor
protease-activated
thrombin thrombosis
ANTIPLATELET THERAPIES
ALLOSTERIC LINKAGE
TISSUE FACTOR
PROTEASE
VORAPAXAR
MECHANISM
REVEALS
SITE
糖胺聚糖寡糖HS14定量分析方法的建立及其药代动力学研究
学位论文
, 2021
Authors:
张桃翠
Adobe PDF(4297Kb)
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Submit date:2024/03/20
Structural characterization and anticoagulant analysis of the novel branched fucosylated glycosaminoglycan from sea cucumber Holothuria nobilis
期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 269, 页码: 118290
Authors:
Li,Shanni
;
Zhong,Wei
;
Pan,Ying
;
Lin,Lisha
;
Cai,Ying
;
Mao,Hui
;
Zhang,Taocui
;
Li,Sujuan
;
Chen,Ru
;
Zhou,Lutan
;
Wang,Weili
;
Cui,Qinghua
;
Yin,Ronghua
;
Huang,Shengxiong
;
Zhao,Jinhua
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View/Download:222/28
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Submit date:2022/04/02
Disaccharide branch
Fucosylated glycosaminoglycan
Holothuria nobilis
Oligosaccharide
Anticoagulant
INTRINSIC TENASE COMPLEX
CHONDROITIN SULFATE
ACAUDINA-MOLPADIOIDEA
FACTOR XASE
HEPARIN
DEPOLYMERIZATION
OLIGOSACCHARIDES
POLYSACCHARIDES
DERIVATIVES
Structural characterization of oligosaccharides from free radical depolymerized fucosylated glycosaminoglycan and suggested mechanism of depolymerization
期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 270, 页码: 118368
Authors:
Chen,Ru
;
Yin,Ronghua
;
Li,Shanni
;
Pan,Ying
;
Mao,Hui
;
Cai,Ying
;
Lin,Lisha
;
Wang,Weili
;
Zhang,Taocui
;
Zhou,Lutan
;
Gao,Na
;
Luo,Xiaodong
;
Zhao,Jinhua
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View/Download:115/31
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Submit date:2022/04/02
Fucosylated glycosaminoglycan
Free radical depolymerization
Chemical structure
Oligosaccharide
NMR
INTRINSIC TENASE COMPLEX
ANTICOAGULANT ACTIVITIES
SEA-CUCUMBER
CHONDROITIN SULFATE
PHYSICOCHEMICAL CHARACTERISTICS
FACTOR XASE
POLYSACCHARIDES
DERIVATIVES
HEPARIN
The Toxicology of Native Fucosylated Glycosaminoglycans and the Safety of Their Depolymerized Products as Anticoagulants
期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 9, 页码: 487
Authors:
Lin,Lisha
;
Li,Sujuan
;
Gao,Na
;
Wang,Weili
;
Zhang,Taocui
;
Yang,Lian
;
Yang,Xingzhi
;
Luo,Dan
;
Ji,Xu
;
Zhao,Jinhua
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View/Download:135/28
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Submit date:2022/04/02
fucosylated glycosaminoglycan
anticoagulant
platelet aggregation
contact activation
hypotension
pulmonary embolism
CHONDROITIN SULFATE
CONTACT SYSTEM
COMPLEMENT
COAGULATION
ACTIVATION
ACCUMULATION
INVOLVEMENT
DERIVATIVES
KALLIKREIN
THROMBOSIS
Pharmacokinetics and Pharmacodynamics of a Depolymerized Glycosaminoglycan from Holothuria fuscopunctata, a Novel Anticoagulant Candidate, in Rats by Bioanalytical Methods
期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 4, 页码: 212
Authors:
Liu,Shuang
;
Zhang,Taocui
;
Sun,Huifang
;
Lin,Lisha
;
Gao,Na
;
Wang,Weili
;
Li,Sujuan
;
Zhao,Jinhua
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Submit date:2022/04/02
pharmacokinetics
pharmacodynamics
anticoagulant
fucosylated glycosaminoglycan
dHG-5
method validation