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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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Pharmacology and anti-addiction effects of the novel kappa opioid receptor agonist Mesyl Sal B, a potent and long-acting analogue of salvinorin A
期刊论文
出版物, 3111, 期号: 0, 页码: 1-53
Authors:
B Simonson
;
A S Morani
;
A W M Ewald
;
L Walker
;
N Kumar
;
D Simpson
;
J H Miller
;
T E Prisinzano
;
B M Kivell
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Submit date:2017/07/24
The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)1
期刊论文
出版物, 3111, 期号: 0, 页码: 1-42
Authors:
C Pergola
;
J Gerstmeier
;
B Monch
;
B Çaliskan
;
S Luderer
;
C Weinige
;
D Barz
;
J Maczewsky
;
S Pace
;
A Rossi
;
L Sautebin
;
E Banoglu
;
O Werz
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Submit date:2017/07/24
The dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2-dependent and -independent fever while 4-AA only blocks PGE2-dependent fever1
期刊论文
出版物, 3111, 期号: 0, 页码: 1-44
Authors:
David do C. Malvar
;
Fernando A. Aguiar
;
Artur de L. L. Vaz
;
Débora C. R. Assis
;
Miriam C. C. de Melo
;
Valquíria A. P. Jabor
;
Evanguedes Kalapothakis
;
Sérgio H. Ferreira
;
Giuliano C. Clososki
;
Glória E. P. de Souza
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Submit date:2017/07/24
Dipyrone
Dipyrone Metabolites
Fever
Hypothermia
Lps
Tityus Serrulatus Venom
Structural characterization and anticoagulant analysis of the novel branched fucosylated glycosaminoglycan from sea cucumber Holothuria nobilis
期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 269, 页码: 118290
Authors:
Li,Shanni
;
Zhong,Wei
;
Pan,Ying
;
Lin,Lisha
;
Cai,Ying
;
Mao,Hui
;
Zhang,Taocui
;
Li,Sujuan
;
Chen,Ru
;
Zhou,Lutan
;
Wang,Weili
;
Cui,Qinghua
;
Yin,Ronghua
;
Huang,Shengxiong
;
Zhao,Jinhua
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Submit date:2022/04/02
Disaccharide branch
Fucosylated glycosaminoglycan
Holothuria nobilis
Oligosaccharide
Anticoagulant
INTRINSIC TENASE COMPLEX
CHONDROITIN SULFATE
ACAUDINA-MOLPADIOIDEA
FACTOR XASE
HEPARIN
DEPOLYMERIZATION
OLIGOSACCHARIDES
POLYSACCHARIDES
DERIVATIVES
Neolignans and Norlignans from Insect Medicine Polyphaga plancyi and Their Biological Activities
期刊论文
Natural products and bioprospecting, 2021, 卷号: 11, 期号: 1, 页码: 51-62
Authors:
Zhu,Hong-Jie
;
Xu,Te
;
Yan,Yong-Ming
;
Tu,Zheng-Chao
;
Cheng,Yong-Xian
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Submit date:2022/04/02
Structural characterization of oligosaccharides from free radical depolymerized fucosylated glycosaminoglycan and suggested mechanism of depolymerization
期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 270, 页码: 118368
Authors:
Chen,Ru
;
Yin,Ronghua
;
Li,Shanni
;
Pan,Ying
;
Mao,Hui
;
Cai,Ying
;
Lin,Lisha
;
Wang,Weili
;
Zhang,Taocui
;
Zhou,Lutan
;
Gao,Na
;
Luo,Xiaodong
;
Zhao,Jinhua
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Submit date:2022/04/02
Fucosylated glycosaminoglycan
Free radical depolymerization
Chemical structure
Oligosaccharide
NMR
INTRINSIC TENASE COMPLEX
ANTICOAGULANT ACTIVITIES
SEA-CUCUMBER
CHONDROITIN SULFATE
PHYSICOCHEMICAL CHARACTERISTICS
FACTOR XASE
POLYSACCHARIDES
DERIVATIVES
HEPARIN
A review on the relationship of mast cells and macrophages in breast cancer - Can herbs or natural products facilitate their anti-tumor effects?
期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 164, 页码: 105321
Authors:
Gou,Leilei
;
Yue,Grace Gar-Lee
;
Puno,Pema Tenzin
;
Lau,Clara Bik-San
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Submit date:2022/04/02
Breast cancer
Mast cell
Macrophage
Natural products
Herbs
Extracts
TUMOR-ASSOCIATED MACROPHAGES
NF-KAPPA-B
MEDIATED ALLERGIC REACTIONS
PRO-INFLAMMATORY CYTOKINES
ANTIINFLAMMATORY ACTIVITY
ATOPIC-DERMATITIS
UMBROSA ROOT
TNF-ALPHA
IN-VIVO
C-KIT
The Toxicology of Native Fucosylated Glycosaminoglycans and the Safety of Their Depolymerized Products as Anticoagulants
期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 9, 页码: 487
Authors:
Lin,Lisha
;
Li,Sujuan
;
Gao,Na
;
Wang,Weili
;
Zhang,Taocui
;
Yang,Lian
;
Yang,Xingzhi
;
Luo,Dan
;
Ji,Xu
;
Zhao,Jinhua
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Submit date:2022/04/02
fucosylated glycosaminoglycan
anticoagulant
platelet aggregation
contact activation
hypotension
pulmonary embolism
CHONDROITIN SULFATE
CONTACT SYSTEM
COMPLEMENT
COAGULATION
ACTIVATION
ACCUMULATION
INVOLVEMENT
DERIVATIVES
KALLIKREIN
THROMBOSIS
Pharmacokinetics and Pharmacodynamics of a Depolymerized Glycosaminoglycan from Holothuria fuscopunctata, a Novel Anticoagulant Candidate, in Rats by Bioanalytical Methods
期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 4, 页码: 212
Authors:
Liu,Shuang
;
Zhang,Taocui
;
Sun,Huifang
;
Lin,Lisha
;
Gao,Na
;
Wang,Weili
;
Li,Sujuan
;
Zhao,Jinhua
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Submit date:2022/04/02
pharmacokinetics
pharmacodynamics
anticoagulant
fucosylated glycosaminoglycan
dHG-5
method validation
High-molecular-weight fucosylated glycosaminoglycan induces human platelet aggregation depending on alpha(IIb)beta(3) and platelet secretion
期刊论文
PLATELETS, 2021, 卷号: 32, 期号: 7, 页码: 975-983
Authors:
Lin,Lisha
;
Yang,Lian
;
Chen,Jun
;
Zhou,Lutan
;
Li,Sujuan
;
Gao,Na
;
Zhao,Jinhua
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Submit date:2022/04/02
Aggregation
fucosylated glycosaminoglycan
human platelets
secretion
alpha(IIb beta 3)
DEPOLYMERIZED HOLOTHURIAN GLYCOSAMINOGLYCAN
INTRINSIC TENASE COMPLEX
INTEGRIN ALPHA(IIB)BETA(3)
ACTIVATION
AGGLUTINATION
RECEPTOR
ADP
INHIBITION
GENERATION
MECHANISM