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Oligosaccharide Blocks PAR1 (Proteinase-Activated Receptor 1)-PAR4-Mediated Platelet Activation by Binding to Thrombin Exosite II and Impairs Thrombosis 期刊论文
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2023, 卷号: 43, 期号: 2, 页码: 253-266
Authors:  Li,Sujuan;  Wang,Weili;  Lin,Lisha;  Yang,Lian;  Cai,Ying;  Yang,Xingzhi;  Zhang,Taocui;  Xiao,Chuang;  Yan,Hui;  Gao,Na;  Zhao,Jinhua
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oligosaccharide  platelet activation  receptor  protease-activated  thrombin thrombosis  ANTIPLATELET THERAPIES  ALLOSTERIC LINKAGE  TISSUE FACTOR  PROTEASE  VORAPAXAR  MECHANISM  REVEALS  SITE  
Structural Characterization and Anticoagulant Activities of a Keratan Sulfate-like Polysaccharide from the Sea Cucumber Holothuria fuscopunctata 期刊论文
MARINE DRUGS, 2023, 卷号: 21, 期号: 12, 页码: 632
Authors:  Chen,Ru;  Wang,Weili;  Yin,Ronghua;  Pan,Ying;  Xu,Chen;  Gao,Na;  Luo,Xiaodong;  Zhao,Jinhua;  Reyes,Fernando
View  |  Adobe PDF(6775Kb)  |  Favorite  |  View/Download：164/40  |  Submit date：2024/05/09
aminoglycan  structural features  keratan sulfate  depolymerization  oligosaccharides  anticoagulant activity  INTRINSIC-FACTOR XASE  GLYCOSAMINOGLYCAN  OLIGOSACCHARIDES  DEPOLYMERIZATION  ELUCIDATION  DERIVATIVES  HEPARIN  
Branched Chondroitin Sulfate Oligosaccharides Derived from the Sea Cucumber Acaudina molpadioides Stimulate Neurite Outgrowth 期刊论文
MARINE DRUGS, 2022, 卷号: 20, 期号: 10, 页码: 653
Authors:  Wang, Weili;  Mao, Hui;  Li, Sujuan;  Zhang, Longlong;  Yang, Lian;  Yin, Ronghua;  Zhao, Jinhua
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fucosylated chondroitin sulfate  sea cucumber  disaccharide branch  oligosaccharide  neurite outgrowth  stimulation  HIPPOCAMPAL-NEURONS  PROMOTING ACTIVITY  GLYCOSAMINOGLYCAN  DISACCHARIDE  INHIBITOR  
Structural characterization and anticoagulant analysis of the novel branched fucosylated glycosaminoglycan from sea cucumber Holothuria nobilis 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 269, 页码: 118290
Authors:  Li,Shanni;  Zhong,Wei;  Pan,Ying;  Lin,Lisha;  Cai,Ying;  Mao,Hui;  Zhang,Taocui;  Li,Sujuan;  Chen,Ru;  Zhou,Lutan;  Wang,Weili;  Cui,Qinghua;  Yin,Ronghua;  Huang,Shengxiong;  Zhao,Jinhua
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Disaccharide branch  Fucosylated glycosaminoglycan  Holothuria nobilis  Oligosaccharide  Anticoagulant  INTRINSIC TENASE COMPLEX  CHONDROITIN SULFATE  ACAUDINA-MOLPADIOIDEA  FACTOR XASE  HEPARIN  DEPOLYMERIZATION  OLIGOSACCHARIDES  POLYSACCHARIDES  DERIVATIVES  
Structural characterization of oligosaccharides from free radical depolymerized fucosylated glycosaminoglycan and suggested mechanism of depolymerization 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 270, 页码: 118368
Authors:  Chen,Ru;  Yin,Ronghua;  Li,Shanni;  Pan,Ying;  Mao,Hui;  Cai,Ying;  Lin,Lisha;  Wang,Weili;  Zhang,Taocui;  Zhou,Lutan;  Gao,Na;  Luo,Xiaodong;  Zhao,Jinhua
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Fucosylated glycosaminoglycan  Free radical depolymerization  Chemical structure  Oligosaccharide  NMR  INTRINSIC TENASE COMPLEX  ANTICOAGULANT ACTIVITIES  SEA-CUCUMBER  CHONDROITIN SULFATE  PHYSICOCHEMICAL CHARACTERISTICS  FACTOR XASE  POLYSACCHARIDES  DERIVATIVES  HEPARIN  
The Toxicology of Native Fucosylated Glycosaminoglycans and the Safety of Their Depolymerized Products as Anticoagulants 期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 9, 页码: 487
Authors:  Lin,Lisha;  Li,Sujuan;  Gao,Na;  Wang,Weili;  Zhang,Taocui;  Yang,Lian;  Yang,Xingzhi;  Luo,Dan;  Ji,Xu;  Zhao,Jinhua
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fucosylated glycosaminoglycan  anticoagulant  platelet aggregation  contact activation  hypotension  pulmonary embolism  CHONDROITIN SULFATE  CONTACT SYSTEM  COMPLEMENT  COAGULATION  ACTIVATION  ACCUMULATION  INVOLVEMENT  DERIVATIVES  KALLIKREIN  THROMBOSIS  
Pharmacokinetics and Pharmacodynamics of a Depolymerized Glycosaminoglycan from Holothuria fuscopunctata, a Novel Anticoagulant Candidate, in Rats by Bioanalytical Methods 期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 4, 页码: 212
Authors:  Liu,Shuang;  Zhang,Taocui;  Sun,Huifang;  Lin,Lisha;  Gao,Na;  Wang,Weili;  Li,Sujuan;  Zhao,Jinhua
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pharmacokinetics  pharmacodynamics  anticoagulant  fucosylated glycosaminoglycan  dHG-5  method validation  
A new fucosylated glycosaminoglycan containing disaccharide branches from Acaudina molpadioides: Unusual structure and anti-intrinsic tenase activity 期刊论文
CARBOHYDRATE POLYMERS, 2020
Authors:  Mao, Hui;  Cai, Ying;  Li, Shanni;  Sun, Huifang;  Lin, Lisha;  Pan, Ying;  Yang, Wenjiao;  He, Zhicheng;  Chen, Ru;  Zhou, Lutan;  Wang, Weili;  Yin, Ronghua;  Zhao, Jinhua
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Comparison of Pixel- and Object-Based Approaches in Phenology-Based Rubber Plantation Mapping in Fragmented Landscapes 期刊论文
REMOTE SENSING, 2018, 卷号: 10, 期号: 1, 页码: 44
Authors:  Zhai, Deli;  Dong, Jinwei;  Cadisch, Georg;  Wang, Mingcheng;  Kou, Weili;  Xu, Jianchu;  Xiao, Xiangming;  Abbas, Sawaid
View  |  Adobe PDF(7544Kb)  |  Favorite  |  View/Download：514/83  |  Submit date：2018/04/28
Rubber (Hevea Brasiliensis) Plantation  Phenology  Xishuangbanna  Landsat  Object-based Approach  Pixel-based Approach  J0101  
Natural Diterpenoid Compound Elevates Expression of Bim Protein, Which Interacts with Antiapoptotic Protein Bcl-2, Converting It to Proapoptotic Bax-like Molecule 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 卷号: 287, 期号: 2, 页码: 1054-1065
Authors:  Zhao, Lixia;  He, Feng;  Liu, Haiyang;  Zhu, Yushan;  Tian, Weili;  Gao, Ping;  He, Hongping;  Yue, Wen;  Lei, Xiaobo;  Ni, Biyun;  Wang, Xiaohui;  Jin, Haijing;  Hao, Xiaojiang;  Lin, Jialing;  Chen, Quan
View  |  Adobe PDF(2908Kb)  |  Favorite  |  View/Download：321/81  |  Submit date：2015/06/17