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Effects of Native Fucosylated Glycosaminoglycan, Its Depolymerized Derivatives on Intrinsic Factor Xase, Coagulation, Thrombosis, and Hemorrhagic Risk 期刊论文
THROMBOSIS AND HAEMOSTASIS, 2020
Authors:  Zhou, Lutan;  Gao, Na;  Sun, Huifang;  Xiao, Chuang;  Yang, Lian;  Lin, Lisha;  Yin, Ronghua;  Li, Zi;  Zhang, Hongbin;  Ji, Xu;  Zhao, Jinhua
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From multi-target anticoagulants to DOACs, and intrinsic coagulation factor inhibitors 期刊论文
BLOOD REVIEWS, 2020
Authors:  Lin, Lisha;  Zhao, Longyan;  Gao, Na;  Yin, Ronghua;  Li, Sujuan;  Sun, Huifang;  Zhou, Lutan;  Zhao, Guiling;  Purcell, Steven W.;  Zhao, Jinhua
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A new fucosylated glycosaminoglycan containing disaccharide branches from Acaudina molpadioides: Unusual structure and anti-intrinsic tenase activity 期刊论文
CARBOHYDRATE POLYMERS, 2020
Authors:  Mao, Hui;  Cai, Ying;  Li, Shanni;  Sun, Huifang;  Lin, Lisha;  Pan, Ying;  Yang, Wenjiao;  He, Zhicheng;  Chen, Ru;  Zhou, Lutan;  Wang, Weili;  Yin, Ronghua;  Zhao, Jinhua
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High-molecular-weight fucosylated glycosaminoglycan induces human platelet aggregation depending on alpha(IIb)beta(3) and platelet secretion 期刊论文
PLATELETS, 2020
Authors:  Lin, Lisha;  Yang, Lian;  Chen, Jun;  Zhou, Lutan;  Li, Sujuan;  Gao, Na;  Zhao, Jinhua
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Precise structures and anti-intrinsic tenase complex activity of three fucosylated glycosaminoglycans and their fragments 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 224, 页码: 10
Authors:  Cai, Ying;  Yang, Wenjiao;  Li, Xiaomei;  Zhou, Lutan;  Wang, Zhongjuan;  Lin, Lisha;  Chen, Dingyuan;  Zhao, Longyan;  Li, Zhongkun;  Liu, Shubai;  Yin, Ronghua;  Zuo, Zhili;  Gao, Na;  Zhao, Jinhua
View  |  Adobe PDF(4714Kb)  |  Favorite  |  View/Download:176/10  |  Submit date:2019/10/28
Fucosylated glycosaminoglycan  Oligosaccharide  Chemical structure  iXase  
Structure and heparanase inhibitory activity of a new glycosaminoglycan from the slug Limacus flavus 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 220, 页码: 176-184
Authors:  He, Zhicheng;  Zhou, Lutan;  Lin, Lisha;  Yin, Ronghua;  Zhao, Jinhua
View  |  Adobe PDF(1875Kb)  |  Favorite  |  View/Download:87/3  |  Submit date:2019/07/29
Slug  Glycosaminoglycan  Chemical structure  Depolymerization  Heparanase inhibition  
Physicochemical Characteristics and Anticoagulant Activities of the Polysaccharides from Sea Cucumber Pattalus mollis 期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 4, 页码: 15
Authors:  Zheng, Wenqi;  Zhou, Lutan;  Lin, Lisha;  Cai, Ying;  Sun, Huifang;  Zhao, Longyan;  Gao, Na;  Yin, Ronghua;  Zhao, Jinhua
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Pattalus mollis  fucosylated glycosaminoglycan  fucan sulfate  physicochemical characteristics  anticoagulant activities  
Synthesis of Fucosylated Chondroitin Sulfate Nonasaccharide as a Novel Anticoagulant Targeting Intrinsic Factor Xase Complex 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 卷号: 57, 期号: 39, 页码: 12880-12885
Authors:  Zhang, Xiao;  Liu, Huiying;  Lin, Lisha;  Yao, Wang;  Zhao, Jinhua;  Wu, Mingyi;  Li, Zhongjun
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Anticoagulants  Drug Discovery  Fucosylated Chondroitin Sulfate  Glycosaminoglycans  Oligosaccharides  
Structural analysis and anticoagulant activities of three highly regular fucan sulfates as novel intrinsic factor Xase inhibitors 期刊论文
CARBOHYDRATE POLYMERS, 2018, 卷号: 195, 页码: 257-266
Authors:  Shang, Feineng;  Mou, Rongrong;  Zhang, Zhidong;  Gao, Na;  Lin, Lisha;  Li, Zhongkun;  Wu, Mingyi;  Zhao, Jinhua
View  |  Adobe PDF(2021Kb)  |  Favorite  |  View/Download:216/28  |  Submit date:2018/07/16
Fucan Sulfate  Chemical Structure  Anticoagulant  Polysaccharide  Sea Cucumber  
Precise structures of fucosylated glycosaminoglycan and its oligosaccharides as novel intrinsic factor Xase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 148, 页码: 423-435
Authors:  Shang, Feineng;  Gao, Na;  Yin, Ronghua;  Lin, Lisha;  Xiao, Chuang;  Zhou, Lutan;  Li, Zi;  Purcell, Steven W.;  Wu, Mingyi;  Zhao, Jinhua
View  |  Adobe PDF(3117Kb)  |  Favorite  |  View/Download:149/27  |  Submit date:2018/05/08
Glycosaminoglycan  Oligosaccharide  Anticoagulant  Intrinsic Factor Xase