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Celastrol as an intestinal FXR inhibitor triggers tripolide-induced intestinal bleeding: Underlying mechanism of gastrointestinal injury induced by Tripterygium wilfordii 期刊论文
PHYTOMEDICINE, 2023, 卷号: 121, 页码: 155054
Authors:  Dai,Manyun;  Peng,Wan;  Lin,Lisha;  Wu,Zhanxuan;  Zhang,Ting;  Zhao,Qi;  Cheng,Yan;  Lin,Qiuxia;  Zhang,Binbin;  Liu,Aiming;  Rao,Qianru;  Huang,Jianfeng;  Zhao,Jinhua;  Gonzalez,Frank J.;  Li,Fei
View  |  Adobe PDF(17974Kb)  |  Favorite  |  View/Download：103/19  |  Submit date：2024/07/17
Intestinal bleeding  Triptolide  Celastrol  Intestinal FXR  Tripterygium wilfordii  FARNESOID-X-RECEPTOR  BACTERIAL TRANSLOCATION  ACTIVATION  INFLAMMATION  DYSFUNCTION  TRIPTOLIDE  MICROBIOTA  PREVENTS  OBESITY  MICE  
Metabolomics reveals the role of PPAR alpha in Tripterygium Wilfordii-induced liver injury 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2022, 卷号: 289, 页码: 16
Authors:  Dai, Manyun;  Peng, Wan;  Zhang, Ting;  Zhao, Qi;  Ma, Xiaofang;  Cheng, Yan;  Wang, Chunyan;  Li, Fei
Favorite  |  View/Download：397/0  |  Submit date：2022/07/15
Tripterygium wilfordii  Liver injury  PPAR alpha  IL6-STAT3  Metabolomics  
Polyamine metabolism links gut microbiota and testicular dysfunction 期刊论文
MICROBIOME, 2021, 卷号: 9, 期号: 1, 页码: 224
Authors:  Zhao,Qi;  Huang,Jian-Feng;  Cheng,Yan;  Dai,Man-Yun;  Zhu,Wei-Feng;  Yang,Xiu-Wei;  Gonzalez,Frank J.;  Li,Fei
Favorite  |  View/Download：106/0  |  Submit date：2022/04/02
Testicular dysfunction  Gut microbiota  Polyamine metabolism  Metabolomics  SMALL-MOLECULE INHIBITOR  ORNITHINE-DECARBOXYLASE  TRIPTOLIDE  SPERMINE  ACTIVATION  DISRUPTION  MECHANISMS  EXPRESSION  APOPTOSIS  TRANSPORT  
FXR activation prevents liver injury induced by Tripterygium wilfordii preparations 期刊论文
XENOBIOTICA, 2021, 卷号: 51, 期号: 6, 页码: 716-727
Authors:  Peng,Wan;  Dai,Man-Yun;  Bao,Li-Juan;  Zhu,Wei-Feng;  Li,Fei
View  |  Adobe PDF(2010Kb)  |  Favorite  |  View/Download：182/20  |  Submit date：2022/04/02
Tripterygium wilfordii  liver injury  farnesoid X receptor  bile acid metabolism  metabolomics  
醋酸棉酚调控细胞自噬发挥抗肿瘤作用的机制研究 学位论文
, 2020
Authors:  蔡碧宬
Adobe PDF(2668Kb)  |  Favorite  |  View/Download：26/0  |  Submit date：2023/11/02
康定鼠尾草中抗血小板活性松香烷二萜的研究 学位论文
, 2020
Authors:  夏凡
Adobe PDF(9707Kb)  |  Favorite  |  View/Download：56/0  |  Submit date：2023/11/02
基于代谢组学研究雷公藤甲素的睾丸毒性和肝毒性 学位论文
, 2020
Authors:  黄建锋
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Isopenicin A和Artemisitene的抗肿瘤活性及作用机制研究 学位论文
, 2020
Authors:  陈琳
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PPARα 在治疗 CCl4 诱导肝损伤中的应用 学位论文
, 2020
Authors:  唐萍
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Effect of CYP3A4 on liver injury induced by triptolide 期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2020
Authors:  Xiao, Xuerong;  Zhang, Ting;  Huang, Jianfeng;  Zhao, Qi;  Li, Fei
View  |  Adobe PDF(4498Kb)  |  Favorite  |  View/Download：182/49  |  Submit date：2021/01/05