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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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Small molecule QF84139 ameliorates cardiac hypertrophy via activating the AMPK signaling pathway
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 3, 页码: 588-601
Authors:
Li,Xu-xia
;
Zhang,Peng
;
Yang,Yang
;
Wang,Jing-jing
;
Zheng,Yan-jun
;
Tan,Ji-liang
;
Liu,Shen-yan
;
Yan,Yong-ming
;
Zhang,You-yi
;
Cheng,Yong-xian
;
Yang,Huang-tian
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  |  
Submit date:2022/04/02
cardiac hypertrophy
pyrazine derivative
QF84139
phenylephrine
transverse aortic constriction
AMPK signaling pathway
PROTEIN-KINASE
MAMMALIAN TARGET
OVERLOAD
METFORMIN
MACROPHAGES
MECHANISMS
MEDICINE
ALPHA
CELLS
MODEL
PXR mediates mifepristone-induced hepatomegaly in mice
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 1, 页码: 146-156
Authors:
Yao,Xin-peng
;
Jiao,Ting-ying
;
Jiang,Yi-ming
;
Fan,Shi-cheng
;
Zhao,Ying-yuan
;
Yang,Xiao
;
Gao,Yue
;
Li,Fei
;
Zhou,Yan-ying
;
Chen,Pan-pan
;
Huang,Min
;
Bi,Hui-chang
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View/Download:1/0
  |  
Submit date:2022/04/02
mifepristone
hepatomegaly
pregnane X receptor (PXR)
yes-associated protein (YAP)
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
Authors:
Zhu,Yan-Yan
;
Jin,Qiong
;
Chen,Shan-Shan
;
Jin,Dan-Ni
;
Wang,Zhao-Jie
;
He,Ying-Jie
;
Chen,Hui-Cheng
;
Zhao,Yun-Li
;
Zhao,Li-Xing
;
Dai,Zhi
;
Luo,Xiao-Dong
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View/Download:7/0
  |  
Submit date:2022/04/02
Neothalfine
Bisbenzylisoquinoline alkaloid
Metastatic colorectal cancer
Metabolomic
Mitochondrial apoptosis
SMALL MOLECULES
IRINOTECAN
RESISTANCE
CELL
IMMUNOTHERAPY
OPPORTUNITIES
CHEMOTHERAPY
VINORELBINE
ALKALOIDS
PATHWAY
Isolation and identification of belamcandaoids A-N from Belamcanda chinensis seeds and their inhibition on extracellular matrix in TGF-beta 1 induced kidney proximal tubular cells
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 114, 页码: 105067
Authors:
Song,Ying-Ying
;
Jiang,Jian-Bing
;
Yan,Yong-Ming
;
Cheng,Yong-Xian
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Submit date:2022/04/02
Belamcanda chinensis
Triterpenoids
TGF-beta 1
Kidney proximal tubular cells
TGF-BETA
TRITERPENOIDS
CONSTITUENTS
Meroterpenoids and alkaloids from Ganoderma australe
期刊论文
NATURAL PRODUCT RESEARCH, 2021, 卷号: 35, 期号: 19, 页码: 3226-3232
Authors:
Zhang,Jiao-Jiao
;
Dong,Yun
;
Qin,Fu-Ying
;
Yan,Yong-Ming
;
Cheng,Yong-Xian
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  |  
Submit date:2022/04/02
Ganoderma australe
meroterpenoids
alkaloids
neuroprotection
LUCIDUM
INHIBITORS
EXTRACT
POTENT
Impatiens shangjiangensis (Balsaminaceae), a new species from Yunnan, China
期刊论文
ANNALES BOTANICI FENNICI, 2021, 卷号: 58, 期号: 4-6, 页码: 197-201
Authors:
Gu,Jian-Zhong
;
Yang,Ning
;
Peng,Yang-Cheng
;
Song,Yong-Xiu
;
Guo,Shi-Wei
;
Cong,Yi-Yan
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  |  
Submit date:2022/04/02
POLLEN
L.
Genetic innovations: Transposable element recruitment and de novo formation lead to the birth of orphan genes in the rice genome
期刊论文
JOURNAL OF SYSTEMATICS AND EVOLUTION, 2021, 卷号: 59, 期号: 2, 页码: 341-351
Authors:
Jin,Gui-Hua
;
Zhou,Yan-Li
;
Yang,Hong
;
Hu,Yan-Ting
;
Shi,Yong
;
Li,Ling
;
Siddique,Abu N.
;
Liu,Chang-Ning
;
Zhu,An-Dan
;
Zhang,Cheng-Jun
;
Li,De-Zhu
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  |  
View/Download:3/0
  |  
Submit date:2022/04/02
comparative genomics
origin
orphan gene
transposable element
LINEAGE-SPECIFIC GENES
EVOLUTION
ORIGIN
IDENTIFICATION
EMERGENCE
PROTEIN
DUPLICATION
ALIGNMENT
SETS
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
Authors:
Dai,Zhi
;
Liu,Hui
;
Wang,Bei
;
Yang,Dong
;
Zhu,Yan-Yan
;
Yan,Huan
;
Zhu,Pei-Feng
;
Liu,Ya-Ping
;
Chen,Hui-Cheng
;
Zhao,Yun-li
;
Zhao,Li-Xing
;
Zhao,Xu-Dong
;
Liu,Hai-Yang
;
Luo,Xiao-Dong
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View/Download:3/0
  |  
Submit date:2022/04/02
Steroidal saponins
Structure-activity relationship
Tribulosaponin A
Glioma stem cells
ROS
SMALL MOLECULES
CARDIAC-ARREST
STEM-CELL
IDENTIFICATION
THERAPY
BRAIN
OPPORTUNITIES
GLIOMA
TUMORS
NOX2
Accession-specific flowering time variation in response to nitrate fluctuation in Arabidopsis thaliana
期刊论文
PLANT DIVERSITY, 2021, 卷号: 43, 期号: 1, 页码: 78-85
Authors:
Yan,Fei-Hong
;
Zhang,Li-Ping
;
Cheng,Fang
;
Yu,Dong-Mei
;
Hu,Jin-Yong
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  |  
Submit date:2022/04/02
Nitrate
Arabidopsis thaliana
Photoperiod
Natural variation
Flowering time
Gene expression
REGULATES FLORAL INDUCTION
ENABLES DROUGHT ESCAPE
LOCUS-T
NITROGEN
GIGANTEA
GIBBERELLIN
METABOLISM
EXPRESSION
GROWTH
Artematrovirenins A-P, guaiane-type sesquiterpenoids with cytotoxicities against two hepatoma cell lines from Artemisia atrovirens
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 114, 页码: 105072
Authors:
Su,Li-Hua
;
Ma,Yun-Bao
;
Geng,Chang-An
;
Li,Tian-Ze
;
Huang,Xiao-Yan
;
Hu,Jing
;
Zhang,Xin
;
Tang,Shuang
;
Shen,Cheng
;
Gao,Zhen
;
Zhang,Xue-Mei
;
Chen,Ji-Jun
Favorite
  |  
View/Download:3/0
  |  
Submit date:2022/04/02
Artemisia atrovirens
guaiane-type sesquiterpenoids
artematrovirenins A-P
HepG2 and Huh7 cell lines
antihepatic cytotoxicity
LACTONES
CONSTITUENTS
GUAIANOLIDES