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Small molecule QF84139 ameliorates cardiac hypertrophy via activating the AMPK signaling pathway 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 3, 页码: 588-601
Authors:  Li,Xu-xia;  Zhang,Peng;  Yang,Yang;  Wang,Jing-jing;  Zheng,Yan-jun;  Tan,Ji-liang;  Liu,Shen-yan;  Yan,Yong-ming;  Zhang,You-yi;  Cheng,Yong-xian;  Yang,Huang-tian
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cardiac hypertrophy  pyrazine derivative  QF84139  phenylephrine  transverse aortic constriction  AMPK signaling pathway  PROTEIN-KINASE  MAMMALIAN TARGET  OVERLOAD  METFORMIN  MACROPHAGES  MECHANISMS  MEDICINE  ALPHA  CELLS  MODEL  
PXR mediates mifepristone-induced hepatomegaly in mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 1, 页码: 146-156
Authors:  Yao,Xin-peng;  Jiao,Ting-ying;  Jiang,Yi-ming;  Fan,Shi-cheng;  Zhao,Ying-yuan;  Yang,Xiao;  Gao,Yue;  Li,Fei;  Zhou,Yan-ying;  Chen,Pan-pan;  Huang,Min;  Bi,Hui-chang
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mifepristone  hepatomegaly  pregnane X receptor (PXR)  yes-associated protein (YAP)  
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
Authors:  Zhu,Yan-Yan;  Jin,Qiong;  Chen,Shan-Shan;  Jin,Dan-Ni;  Wang,Zhao-Jie;  He,Ying-Jie;  Chen,Hui-Cheng;  Zhao,Yun-Li;  Zhao,Li-Xing;  Dai,Zhi;  Luo,Xiao-Dong
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Neothalfine  Bisbenzylisoquinoline alkaloid  Metastatic colorectal cancer  Metabolomic  Mitochondrial apoptosis  SMALL MOLECULES  IRINOTECAN  RESISTANCE  CELL  IMMUNOTHERAPY  OPPORTUNITIES  CHEMOTHERAPY  VINORELBINE  ALKALOIDS  PATHWAY  
Isolation and identification of belamcandaoids A-N from Belamcanda chinensis seeds and their inhibition on extracellular matrix in TGF-beta 1 induced kidney proximal tubular cells 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 114, 页码: 105067
Authors:  Song,Ying-Ying;  Jiang,Jian-Bing;  Yan,Yong-Ming;  Cheng,Yong-Xian
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Belamcanda chinensis  Triterpenoids  TGF-beta 1  Kidney proximal tubular cells  TGF-BETA  TRITERPENOIDS  CONSTITUENTS  
Meroterpenoids and alkaloids from Ganoderma australe 期刊论文
NATURAL PRODUCT RESEARCH, 2021, 卷号: 35, 期号: 19, 页码: 3226-3232
Authors:  Zhang,Jiao-Jiao;  Dong,Yun;  Qin,Fu-Ying;  Yan,Yong-Ming;  Cheng,Yong-Xian
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Ganoderma australe  meroterpenoids  alkaloids  neuroprotection  LUCIDUM  INHIBITORS  EXTRACT  POTENT  
Impatiens shangjiangensis (Balsaminaceae), a new species from Yunnan, China 期刊论文
ANNALES BOTANICI FENNICI, 2021, 卷号: 58, 期号: 4-6, 页码: 197-201
Authors:  Gu,Jian-Zhong;  Yang,Ning;  Peng,Yang-Cheng;  Song,Yong-Xiu;  Guo,Shi-Wei;  Cong,Yi-Yan
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POLLEN  L.  
Genetic innovations: Transposable element recruitment and de novo formation lead to the birth of orphan genes in the rice genome 期刊论文
JOURNAL OF SYSTEMATICS AND EVOLUTION, 2021, 卷号: 59, 期号: 2, 页码: 341-351
Authors:  Jin,Gui-Hua;  Zhou,Yan-Li;  Yang,Hong;  Hu,Yan-Ting;  Shi,Yong;  Li,Ling;  Siddique,Abu N.;  Liu,Chang-Ning;  Zhu,An-Dan;  Zhang,Cheng-Jun;  Li,De-Zhu
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comparative genomics  origin  orphan gene  transposable element  LINEAGE-SPECIFIC GENES  EVOLUTION  ORIGIN  IDENTIFICATION  EMERGENCE  PROTEIN  DUPLICATION  ALIGNMENT  SETS  
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
Authors:  Dai,Zhi;  Liu,Hui;  Wang,Bei;  Yang,Dong;  Zhu,Yan-Yan;  Yan,Huan;  Zhu,Pei-Feng;  Liu,Ya-Ping;  Chen,Hui-Cheng;  Zhao,Yun-li;  Zhao,Li-Xing;  Zhao,Xu-Dong;  Liu,Hai-Yang;  Luo,Xiao-Dong
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Steroidal saponins  Structure-activity relationship  Tribulosaponin A  Glioma stem cells  ROS  SMALL MOLECULES  CARDIAC-ARREST  STEM-CELL  IDENTIFICATION  THERAPY  BRAIN  OPPORTUNITIES  GLIOMA  TUMORS  NOX2  
Accession-specific flowering time variation in response to nitrate fluctuation in Arabidopsis thaliana 期刊论文
PLANT DIVERSITY, 2021, 卷号: 43, 期号: 1, 页码: 78-85
Authors:  Yan,Fei-Hong;  Zhang,Li-Ping;  Cheng,Fang;  Yu,Dong-Mei;  Hu,Jin-Yong
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Nitrate  Arabidopsis thaliana  Photoperiod  Natural variation  Flowering time  Gene expression  REGULATES FLORAL INDUCTION  ENABLES DROUGHT ESCAPE  LOCUS-T  NITROGEN  GIGANTEA  GIBBERELLIN  METABOLISM  EXPRESSION  GROWTH  
Artematrovirenins A-P, guaiane-type sesquiterpenoids with cytotoxicities against two hepatoma cell lines from Artemisia atrovirens 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 114, 页码: 105072
Authors:  Su,Li-Hua;  Ma,Yun-Bao;  Geng,Chang-An;  Li,Tian-Ze;  Huang,Xiao-Yan;  Hu,Jing;  Zhang,Xin;  Tang,Shuang;  Shen,Cheng;  Gao,Zhen;  Zhang,Xue-Mei;  Chen,Ji-Jun
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Artemisia atrovirens  guaiane-type sesquiterpenoids  artematrovirenins A-P  HepG2 and Huh7 cell lines  antihepatic cytotoxicity  LACTONES  CONSTITUENTS  GUAIANOLIDES