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Impaired clearance of sunitinib leads to metabolic disorders and hepatotoxicity 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2162-2178
Authors:  Zhao, Qi;  Zhang, Ting;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Wang, Yan;  Gonzalez, Frank J.;  Li, Fei
Favorite  |  View/Download:7/0  |  Submit date:2019/07/29
Basal PPAR alpha inhibits bile acid metabolism adaptation in chronic cholestatic model induced by alpha-naphthylisothiocyanate 期刊论文
TOXICOLOGY LETTERS, 2019, 卷号: 300, 页码: 31-39
Authors:  Hua, Huiying;  Dai, Manyun;  Luo, Yishuang;  Lin, Hante;  Xu, Gangming;  Hu, Xiaowei;  Xu, Liping;  Zhang, Haoyue;  Tang, Zhiyuan;  Chang, Liming;  Liu, Aiming;  Yang, Julin
Favorite  |  View/Download:172/0  |  Submit date:2018/12/18
PPAR alpha  FXR pathway  Alpha-naphthylisothiocyanate  Chronic cholestasis  
12th全国天然有机化学学术会议摘要集 会议录
Editors:  中国化学会
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PPAR alpha Mediates the Hepatoprotective Effects of Nutmeg 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2018, 卷号: 17, 期号: 5, 页码: 1887-1897
Authors:  Yang, Xiao-Nan;  Liu, Xue-Mei;  Fang, Jian-He;  Zhu, Xu;  Yang, Xiu-Wei;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(2643Kb)  |  Favorite  |  View/Download:91/12  |  Submit date:2018/07/02
Nutmeg  Hepatoprotective Activity  Metabolomics  Myrislignan  Ppar Alpha  
Targeted Metabolomics Reveals a Protective Role for Basal PPAR alpha in Cholestasis Induced by alpha-Naphthylisothiocyanate 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2018, 卷号: 17, 期号: 4, 页码: 1500-1508
Authors:  Dai, Manyun;  Hua, Huiying;  Lin, Hante;  Xu, Gangming;  Hu, Xiaowei;  Li, Fei;  Gonzalez, Frank J.;  Liu, Aiming;  Yang, Julin
View  |  Adobe PDF(2087Kb)  |  Favorite  |  View/Download:65/6  |  Submit date:2018/05/08
Ppar Alpha  Nf-kappa b  Stat3  Alpha-naphthylisothiocyanate  Cholestasis  
Metabolic map of osthole and its effect on lipids 期刊论文
XENOBIOTICA, 2018, 卷号: 48, 期号: 3, 页码: 285-299
Authors:  Zhao, Qi;  Li, Xin-Mei;  Liu, Hong-Ning;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(2482Kb)  |  Favorite  |  View/Download:139/23  |  Submit date:2017/11/17
Lipid  Metabolomics  Metabolic Disease  Osthole  Time-of-flight Mass Spectrometry  Ultra-performance Liquid Chromatography  
三种植物的次生代谢产物及其生物功能研究 学位论文
: 中国科学院大学, 2017
Authors:  华娟
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Borapetoside E 对高脂饮食诱导小鼠糖脂代谢的影响及其机制研究 学位论文
: 中国科学院大学, 2017
Authors:  许宇辉
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Potential role of CYP1B1 in the development and treatment of metabolic diseases 期刊论文
PHARMACOLOGY & THERAPEUTICS, 2017, 卷号: 178, 页码: 18-30
Authors:  Li, Fei;  Zhu, Weifeng;  Gonzalez, Frank J.
View  |  Adobe PDF(2083Kb)  |  Favorite  |  View/Download:61/11  |  Submit date:2017/11/20
Cyp1b1  Metabolic Diseases  Metabolic Pathways  Metabolomics  
PPAR alpha activation protects against cholestatic liver injury 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 9967
Authors:  Zhao, Qi;  Yang, Rui;  Wang, Jing;  Hu, Dan-Dan;  Li, Fei
View  |  Adobe PDF(7693Kb)  |  Favorite  |  View/Download:94/8  |  Submit date:2017/10/23
Primary Biliary-cirrhosis  Bile-acid Homeostasis  Receptor-alpha  Ursodeoxycholic Acid  Cholesterol 7-alpha-hydroxylase  Beta-oxidation  Fenofibrate  Therapy  Mice  Hepatotoxicity