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seco-Prezizanne Sesquiterpenes and Prenylated C6-C3 Compounds from the Fruits of Illicium lanceolatum A. C. Smith 期刊论文
CHEMISTRY & BIODIVERSITY, 2022, 卷号: 19, 期号: 1, 页码: e202100868
Authors:  Nie,Wei;  Ding,Lin-Fen;  Tie-Lei;  Zhou,Hao-Feng;  Bao,Yi;  Song,Liu-Dong;  Pan,Zheng-Hong;  Wu,Xing-De;  Zhao,Qin-Shi
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Illicium lanceolatum A  C  Smith  seco-prezizanne sesquiterpene  prenylated C6-C3 compound  neuroprotective activity  NEUROTROPHIC ACTIVITY  C-6-C-3 COMPOUNDS  STEM BARK  ROOTS  SKELETON  
An efficient and concise synthesis of a selective small molecule non-peptide inhibitor of cathepsin L: KGP94 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105317
Authors:  Munikishore,Rachakunta;  Wang,Liang-Liang;  Zhang,Shuqun;  Zhao,Qin-Shi;  Zuo,Zhili
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Cathepsin L  small-molecule inhibitor  gram-scale synthesis  KGP94  cancer  FUNCTIONALIZED BENZOPHENONE  BIOLOGICAL EVALUATION  TUMOR PROGRESSION  CELL INVASION  EXPRESSION  ANALOGS  SUPPRESSION  DERIVATIVES  ACID  
Polar auxin transport May Be responsive to specific features of flavonoid structure 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 185, 页码: 112702
Authors:  Zhang,Xudong;  Huang,Xing;  Li,Yan;  Tao,Faqing;  Zhao,Qinshi;  Li,Weiqi
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Arabidopsis thaliana  Brassicaceae  Polar auxin transport  Flovonoids  Scutellarin  Scutellarein  Naringenin  Root growth  WUS-RELATED HOMEOBOX 5  
Polar auxin transport May Be responsive to specific features of flavonoid structure (vol 185, 112702, 2021) 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 188, 页码: 112801
Authors:  Zhang,Xudong;  Huang,Xing;  Li,Yan;  Tao,Faqing;  Zhao,Qinshi;  Li,Weiqi
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Monoterpene Indole Alkaloids with Ca(v)3.1 T-Type Calcium Channel Inhibitory Activity from Catharanthus roseus 期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 21, 页码: 6516
Authors:  Deng,Zhen-Tao;  Li,Wen-Yan;  Wang,Lei;  Zhou,Zhi-Ping;  Wu,Xing-De;  Ding,Zhong-Tao;  Zhao,Qin-Shi
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Catharanthus roseus  monoterpene indole alkaloid  catharanosine A  Ca(v)3  1 low voltage-gated calcium channel (LVGCC)  VINCA ALKALOIDS  CELL-PROLIFERATION  N-OXIDE  SARPAGINE  BIOSYNTHESIS  VINORELBINE  VINBLASTINE  MECHANISM  ROOTS  BASES  
An Approach for the Synthesis of Pyrazolo[1,5-a]pyrimidines via Cu(II)-Catalyzed [3+3] Annulation of Saturated Ketones with Aminopyrazoles 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 18, 页码: 12762-12771
Authors:  Ren,Jian;  Ding,Shihua;  Li,Xiaonian;  Bi,Ran;  Zhao,Qinshi
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BIOLOGICAL EVALUATION  REGIOSELECTIVE SYNTHESIS  CASCADE REACTIONS  FUNCTIONALIZATION  DEHYDROGENATION  DISCOVERY  POTENT  BOND  SAR  
Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963
Authors:  Liu,Jiangxin;  Wu,Xing-De;  Li,Wenyan;  Yuan,Zaifeng;  Yang,Kun;  Zhao,Qin-Shi
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Pseudolaric acid A  Hsp90 inhibitor  Apoptosis  NMR  Structure-activity relationship  Photoaffinity-based probe  Protein-ligand interaction  MOLECULAR CHAPERONE  PROTEIN  TARGET  CANCER  KINASE  NMR  IDENTIFICATION  SELECTIVITY  BINDING  DESIGN  
Cunlanceloic acids A-D: unprecedented labdane diterpenoid dimers with AChE inhibitory and cytotoxic activities from Cunninghamia lanceolata 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2021, 卷号: 8, 期号: 20, 页码: 5777-5784
Authors:  Wu,Xing-De;  Ding,Lin-Fen;  Chen,Bin;  Li,Xiao-Nian;  Peng,Li-Yan;  Zhao,Qin-Shi
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ASYMMETRIC-SYNTHESIS  WOOD  SESQUITERPENOIDS  LEAVES  ROOTS  
Rhynchines A-E: Ca(v)3.1 Calcium Channel Blockers from Uncaria rhynchophylla 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 24, 页码: 9463-9467
Authors:  Zhou,Hao-Feng;  Li,Wen-Yan;  Peng,Li-Yan;  Li,Xiao-Nian;  Zuo,Zhi-Li;  Zhao,Qin-Shi
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INDOLE ALKALOIDS  
Neo-clerodane Diterpenoids with Hypoglycemic Effects in Vivo from the Aerial Parts of Salvia hispanica L. 期刊论文
CHEMISTRY & BIODIVERSITY, 2021, 卷号: 18, 期号: 9, 页码: e2100517
Authors:  Fan,Min;  Wang,Ting;  Peng,Li-Yan;  Huang,Jun-Shang;  Wu,Xing-De;  Wang,He-Yao;  Zhao,Qin-Shi
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Salvia hispanica  neo-clerodane diterpenoid  salvihispin H  type 2 diabetes mellitus  GLUCOSE-TOLERANCE  RISK-FACTORS  THERAPY