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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
Authors:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
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Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
The compound BTB06584 is an IF1-dependent selective inhibitor of the mitochondrial F1Fo-ATPase1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-38
Authors:  Fabrice Ivanes;  Danilo Faccenda;  Jemma Gatliff;  Ahmed A Ahmed;  Stefania Cocco;  Carol Ho Ka Cheng;  Emma Allan;  Claire Russell;  Michael R Duchen;  Michelangelo Campanella
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Mitochondrial F1fo Atp Synthase  If1  Ischemia-induced Death  Btb06584  Pinotage  
Anti-arthritis effects of (E)-2,4-bis(p-hydroxyphenyl)-2-butenal through inhibition of STAT3 pathway 期刊论文
出版物, 3111, 期号: 0, 页码: 1-50
Authors:  Jung Ok Ban;  Dae Hwan Kim;  Hee Pom Lee;  Chul Ju Hwang;  Jung-Hyun Shim;  Dae Joong Kim;  Tae Myoung Kim;  Heon Sang Jeong;  Seong Su Nah;  Hanyong Chen;  Zigang Dong;  Young Wan Ham;  Youngsoo Kim;  Sang-Bae Han;  Jin Tae Hong
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Effector-triggered immunity by the plantpathogen Phytophthora 期刊论文
TRENDS in Microbiology, 3111, 卷号: 14, 期号: 11, 页码: 470-473
Authors:  Dinah Qutob;  Jennifer Tedman-Jones;  Mark Gijzen
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Celastrol as an intestinal FXR inhibitor triggers tripolide-induced intestinal bleeding: Underlying mechanism of gastrointestinal injury induced by Tripterygium wilfordii 期刊论文
PHYTOMEDICINE, 2023, 卷号: 121, 页码: 155054
Authors:  Dai,Manyun;  Peng,Wan;  Lin,Lisha;  Wu,Zhanxuan;  Zhang,Ting;  Zhao,Qi;  Cheng,Yan;  Lin,Qiuxia;  Zhang,Binbin;  Liu,Aiming;  Rao,Qianru;  Huang,Jianfeng;  Zhao,Jinhua;  Gonzalez,Frank J.;  Li,Fei
View  |  Adobe PDF(17974Kb)  |  Favorite  |  View/Download：108/19  |  Submit date：2024/07/17
Intestinal bleeding  Triptolide  Celastrol  Intestinal FXR  Tripterygium wilfordii  FARNESOID-X-RECEPTOR  BACTERIAL TRANSLOCATION  ACTIVATION  INFLAMMATION  DYSFUNCTION  TRIPTOLIDE  MICROBIOTA  PREVENTS  OBESITY  MICE  
Rearranged Homoadamantane-Type Polycyclic Polyprenylated Acylphloroglucinols from Hypericum pseudohenryi 期刊论文
ORGANIC LETTERS, 2023, 卷号: 25, 期号: 50, 页码: 8965-8969
Authors:  Jiang,Na-Na;  Ye,Yan-Song;  Liu,Xia;  Wang,Yong-Ling;  Xu,Gang
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Identification of New Diterpenoids from the Pulp of Coffea arabica and Their α-Glucosidase Inhibition Activity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2023, 卷号: 72, 期号: 3, 页码: 1683-1694
Authors:  Al-Romaima,Abdulbaset;  Hu,Guilin;  Wang,Yanbing;  Quan,Chenxi;  Dai,Haopeng;  Qiu,Minghua
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Coffeaarabica  coffee pulp  diterpenoids  structure elucidation  alpha-glucosidase  moleculardocking  ENT-KAURANE DITERPENES  ACID  PRODUCTS  EXTRACTS  CAFFEINE  CAFESTOL  ESTERS  BEANS  
Discovery of potential novel TRPC5 inhibitors by virtual screening and bioassay 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 94, 页码: 117477
Authors:  Shen,Meiling;  Li,Lingfeng;  Li,Yue;  Gu,Xi;  Bai,Longhui;  Xia,Chengfeng;  Xiong,Wenyong;  Zuo,Zhili
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TRPC5  Inhibitors  Virtual screening  Ca 2+channel  CHANNELS  IDENTIFICATION  PERMEABILITY  CALCIUM  
Structurally modified Cyclovirobuxine-D Buxus alkaloids as effective analgesic agents through Cav3.2 T-Type calcium channel inhibition 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106493
Authors:  Munikishore,Rachakunta;  Liu,Rui;  Zhang,Shuqun;  Zhao,Qin-Shi;  Nian,Yin;  Zuo,Zhili
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Buxus alkaloid  Structural modification  T -type calcium channel  Analgesic activity  Docking analysis  Structure -activity relationship study  BUXOZINE-C  SEMPERVIRENS  RING  CONSTITUTION  
Genomic and structural basis for evolution of tropane alkaloid biosynthesis 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 17, 页码: e2302448120
Authors:  Wang,Yong-Jiang;  Tain,Tian;  Yu,Jia-Yi;  Li,Jie;  Xu,Bingyan;  Chen,Jianghua;  D'Auria,John C.;  Huang,Jian-Ping;  Huang,Sheng-Xiong
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tropane alkaloids  evolution  biosynthesis  genome  structural biology  METHYLTRANSFERASE  REVEAL