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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
Authors:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
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Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
Enantioselective Iridium-Catalyzed Allylic Alkylation of Racemic Branched Alkyl-Substituted Allylic Acetates with Malonates 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 3, 页码: 1086-1089
Authors:  Zhang,Tian-Yuan;  Deng,Yi;  Wei,Kun;  Yang,Yu-Rong
View  |  Adobe PDF(920Kb)  |  Favorite  |  View/Download：162/34  |  Submit date：2022/04/02
DIASTEREO  
基于代谢组学研究雷公藤甲素的睾丸毒性和肝毒性 学位论文
, 2020
Authors:  黄建锋
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Impaired clearance of sunitinib leads to metabolic disorders and hepatotoxicity 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2162-2178
Authors:  Zhao, Qi;  Zhang, Ting;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Wang, Yan;  Gonzalez, Frank J.;  Li, Fei
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A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice 期刊论文
XENOBIOTICA, 2019, 卷号: 49, 期号: 6, 页码: 655-670
Authors:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Liang, Wei-Qing;  Xiao, Yao;  Zhao, Qi;  Xiao, Xue-Rong;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(1101Kb)  |  Favorite  |  View/Download：376/130  |  Submit date：2019/07/29
Pazopanib  hepatotoxicity  metabolomics  oxidative stress  ultra-performance liquid chromatography-electrospray ion source-quadrupole  time-of-flight mass spectrometer (UPLC-ESI-QTOFMS)  
胆汁淤积性肝损伤的药物治疗研究 学位论文
博士: 中国科学院昆明植物研究所, 2019
Authors:  赵琦
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非诺贝特  雷公藤红素  胆汁淤积  肝纤维化  代谢组学  
基于脂质组学研究雷公藤红素的降脂作用 学位论文
硕士: 中国科学院昆明植物研究所, 2019
Authors:  张婷
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雷公藤红素  脂质组学  脂质代谢,  Uplc-qtof-ms  
Celastrol Protects From Cholestatic Liver Injury Through Modulation of SIRT1-FXR Signaling 期刊论文
MOLECULAR & CELLULAR PROTEOMICS, 2019, 卷号: 18, 期号: 3, 页码: 520-533
Authors:  Zhao, Qi;  Liu, Fang;  Cheng, Yan;  Xiao, Xue-Rong;  Hu, Dan-Dan;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
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Modulation of Lipid Metabolism by Celastrol 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 3, 页码: 1133-1144
Authors:  Zhang, Ting;  Zhao, Qi;  Xiao, Xuerong;  Yang, Rui;  Hu, Dandan;  Zhu, Xu;  Gonzalez, Frank J.;  Li, Fei
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celastrol  lipidomics  hyperlipidemia  LC-MS  
Basal PPAR alpha inhibits bile acid metabolism adaptation in chronic cholestatic model induced by alpha-naphthylisothiocyanate 期刊论文
TOXICOLOGY LETTERS, 2019, 卷号: 300, 页码: 31-39
Authors:  Hua, Huiying;  Dai, Manyun;  Luo, Yishuang;  Lin, Hante;  Xu, Gangming;  Hu, Xiaowei;  Xu, Liping;  Zhang, Haoyue;  Tang, Zhiyuan;  Chang, Liming;  Liu, Aiming;  Yang, Julin
View  |  Adobe PDF(3156Kb)  |  Favorite  |  View/Download：419/59  |  Submit date：2018/12/18
PPAR alpha  FXR pathway  Alpha-naphthylisothiocyanate  Chronic cholestasis