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Diverse aging rates in ectothermic tetrapods provide insights for the evolution of aging and longevity 期刊论文
SCIENCE, 2022, 卷号: 376, 期号: 6600, 页码: 1459-+
Authors:  Reinke, Beth A.;  Cayuela, Hugo;  Janzen, Fredric J.;  Lemaitre, Jean-Francois;  Gaillard, Jean-Michel;  Lawing, A. Michelle;  Iverson, John B.;  Christiansen, Ditte G.;  Martinez-Solano, Inigo;  Sanchez-Montes, Gregorio;  Gutierrez-Rodriguez, Jorge;  Rose, Francis L.;  Nelson, Nicola;  Keall, Susan;  Crivelli, Alain J.;  Nazirides, Theodoros;  Grimm-Seyfarth, Annegret;  Henle, Klaus;  Mori, Emiliano;  Guiller, Gaetan;  Homan, Rebecca;  Olivier, Anthony;  Muths, Erin;  Hossack, Blake R.;  Bonnet, Xavier;  Pilliod, David S.;  Lettink, Marieke;  Whitaker, Tony;  Schmidt, Benedikt R.;  Gardner, Michael G.;  Cheylan, Marc;  Poitevin, Francoise;  Golubovic, Ana;  Tomovic, Ljiljana;  Arsovski, Dragan;  Griffiths, Richard A.;  Arntzen, Jan W.;  Baron, Jean-Pierre;  Le Galliard, Jean-Francois;  Tully, Thomas;  Luiselli, Luca;  Capula, Massimo;  Rugiero, Lorenzo;  McCaffery, Rebecca;  Eby, Lisa A.;  Briggs-Gonzalez, Venetia;  Mazzotti, Frank;  Pearson, David;  Lambert, Brad A.;  Green, David M.;  Jreidini, Nathalie;  Angelini, Claudio;  Pyke, Graham;  Thirion, Jean-Marc;  Joly, Pierre;  Lena, Jean-Paul;  Tucker, Anton D.;  Limpus, Col;  Priol, Pauline;  Besnard, Aurelien;  Bernard, Pauline;  Stanford, Kristin;  King, Richard;  Garwood, Justin;  Bosch, Jaime;  Souza, Franco L.;  Bertoluci, Jaime;  Famelli, Shirley;  Grossenbacher, Kurt;  Lenzi, Omar;  Matthews, Kathleen;  Boitaud, Sylvain;  Olson, Deanna H.;  Jessop, Tim S.;  Gillespie, Graeme R.;  Clobert, Jean;  Richard, Murielle;  Valenzuela-Sanchez, Andres;  Fellers, Gary M.;  Kleeman, Patrick M.;  Halstead, Brian J.;  Grant, Evan H. Campbell;  Byrne, Phillip G.;  Fretey, Thierry;  Le Garff, Bernard;  Levionnois, Pauline;  Maerz, John C.;  Pichenot, Julian;  Olgun, Kurtulus;  Uzum, Nazan;  Avci, Aziz;  Miaud, Claude;  Elmberg, Johan;  Brown, Gregory P.;  Shine, Richard;  Bendik, Nathan F.;  O'Donnell, Lisa;  Davis, Courtney L.;  Lannoo, Michael J.;  Stiles, Rochelle M.;  Cox, Robert M.;  Reedy, Aaron M.;  Warner, Daniel A.;  Bonnaire, Eric;  Grayson, Kristine;  Ramos-Targarona, Roberto;  Baskale, Eyup;  Munoz, David;  Measey, John;  de Villiers, F. Andre;  Selman, Will;  Ronget, Victor;  Bronikowski, Anne M.;  Miller, David A. W.
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Polyamine metabolism links gut microbiota and testicular dysfunction 期刊论文
MICROBIOME, 2021, 卷号: 9, 期号: 1, 页码: 224
Authors:  Zhao,Qi;  Huang,Jian-Feng;  Cheng,Yan;  Dai,Man-Yun;  Zhu,Wei-Feng;  Yang,Xiu-Wei;  Gonzalez,Frank J.;  Li,Fei
Favorite  |  View/Download:29/0  |  Submit date:2022/04/02
Testicular dysfunction  Gut microbiota  Polyamine metabolism  Metabolomics  SMALL-MOLECULE INHIBITOR  ORNITHINE-DECARBOXYLASE  TRIPTOLIDE  SPERMINE  ACTIVATION  DISRUPTION  MECHANISMS  EXPRESSION  APOPTOSIS  TRANSPORT  
Celastrol ameliorates acute liver injury through modulation of PPAR alpha 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020
Authors:  Zhao, Qi;  Tang, Ping;  Zhang, Ting;  Huang, Jian-Feng;  Xiao, Xue-Rong;  Zhu, Wei-Feng;  Gonzalez, Frank J.;  Li, Fei
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Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
Authors:  Yang, Xiao-Nan;  Wang, Yi-Kun;  Zhu, Xu;  Xiao, Xue-Rong;  Dai, Man-Yun;  Zhang, Ting;  Qu, Yan;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(9057Kb)  |  Favorite  |  View/Download:171/37  |  Submit date:2020/03/26
The Protective Roles of PPAR alpha Activation in Triptolide-Induced Liver Injury 期刊论文
TOXICOLOGICAL SCIENCES, 2019, 卷号: 171, 期号: 1, 页码: 1-12
Authors:  Hu, Dan-Dan;  Zhao, Qi;  Cheng, Yan;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Qu, Yan;  Li, Xian;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(1740Kb)  |  Favorite  |  View/Download:164/21  |  Submit date:2020/03/26
liver injury  metabolomics  PPAR alpha  acylcarnitines  
Role of Metabolic Activation in Elemicin-Induced Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 29, 页码: 8243-8252
Authors:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Zhu, Xu;  Xiao, Xue-Rong;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(3136Kb)  |  Favorite  |  View/Download:150/55  |  Submit date:2019/09/10
elemicin  l'-hydroxyelemicin  metabolic activation  cytotoxicity  
Impaired clearance of sunitinib leads to metabolic disorders and hepatotoxicity 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2162-2178
Authors:  Zhao, Qi;  Zhang, Ting;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Wang, Yan;  Gonzalez, Frank J.;  Li, Fei
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A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice 期刊论文
XENOBIOTICA, 2019, 卷号: 49, 期号: 6, 页码: 655-670
Authors:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Liang, Wei-Qing;  Xiao, Yao;  Zhao, Qi;  Xiao, Xue-Rong;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(1101Kb)  |  Favorite  |  View/Download:205/95  |  Submit date:2019/07/29
Pazopanib  hepatotoxicity  metabolomics  oxidative stress  ultra-performance liquid chromatography-electrospray ion source-quadrupole  time-of-flight mass spectrometer (UPLC-ESI-QTOFMS)  
Celastrol Protects From Cholestatic Liver Injury Through Modulation of SIRT1-FXR Signaling 期刊论文
MOLECULAR & CELLULAR PROTEOMICS, 2019, 卷号: 18, 期号: 3, 页码: 520-533
Authors:  Zhao, Qi;  Liu, Fang;  Cheng, Yan;  Xiao, Xue-Rong;  Hu, Dan-Dan;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(4782Kb)  |  Favorite  |  View/Download:144/56  |  Submit date:2019/07/29
Modulation of Lipid Metabolism by Celastrol 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 3, 页码: 1133-1144
Authors:  Zhang, Ting;  Zhao, Qi;  Xiao, Xuerong;  Yang, Rui;  Hu, Dandan;  Zhu, Xu;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(5774Kb)  |  Favorite  |  View/Download:264/62  |  Submit date:2019/04/15
celastrol  lipidomics  hyperlipidemia  LC-MS