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Role of Metabolic Activation in Elemicin-Induced Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 29, 页码: 8243-8252
Authors:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Zhu, Xu;  Xiao, Xue-Rong;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
Favorite  |  View/Download:3/0  |  Submit date:2019/09/10
elemicin  l'-hydroxyelemicin  metabolic activation  cytotoxicity  
Impaired clearance of sunitinib leads to metabolic disorders and hepatotoxicity 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2162-2178
Authors:  Zhao, Qi;  Zhang, Ting;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Wang, Yan;  Gonzalez, Frank J.;  Li, Fei
Favorite  |  View/Download:12/0  |  Submit date:2019/07/29
A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice 期刊论文
XENOBIOTICA, 2019, 卷号: 49, 期号: 6, 页码: 655-670
Authors:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Liang, Wei-Qing;  Xiao, Yao;  Zhao, Qi;  Xiao, Xue-Rong;  Gonzalez, Frank J.;  Li, Fei
Favorite  |  View/Download:23/0  |  Submit date:2019/07/29
Pazopanib  hepatotoxicity  metabolomics  oxidative stress  ultra-performance liquid chromatography-electrospray ion source-quadrupole  time-of-flight mass spectrometer (UPLC-ESI-QTOFMS)  
Modulation of Lipid Metabolism by Celastrol 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 3, 页码: 1133-1144
Authors:  Zhang, Ting;  Zhao, Qi;  Xiao, Xuerong;  Yang, Rui;  Hu, Dandan;  Zhu, Xu;  Gonzalez, Frank J.;  Li, Fei
Favorite  |  View/Download:88/0  |  Submit date:2019/04/15
celastrol  lipidomics  hyperlipidemia  LC-MS  
Celastrol Protects From Cholestatic Liver Injury Through Modulation of SIRT1-FXR Signaling 期刊论文
MOLECULAR & CELLULAR PROTEOMICS, 2019, 卷号: 18, 期号: 3, 页码: 520-533
Authors:  Zhao, Qi;  Liu, Fang;  Cheng, Yan;  Xiao, Xue-Rong;  Hu, Dan-Dan;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
Favorite  |  View/Download:6/0  |  Submit date:2019/07/29
PPAR alpha Mediates the Hepatoprotective Effects of Nutmeg 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2018, 卷号: 17, 期号: 5, 页码: 1887-1897
Authors:  Yang, Xiao-Nan;  Liu, Xue-Mei;  Fang, Jian-He;  Zhu, Xu;  Yang, Xiu-Wei;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(2643Kb)  |  Favorite  |  View/Download:92/12  |  Submit date:2018/07/02
Nutmeg  Hepatoprotective Activity  Metabolomics  Myrislignan  Ppar Alpha  
Targeted Metabolomics Reveals a Protective Role for Basal PPAR alpha in Cholestasis Induced by alpha-Naphthylisothiocyanate 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2018, 卷号: 17, 期号: 4, 页码: 1500-1508
Authors:  Dai, Manyun;  Hua, Huiying;  Lin, Hante;  Xu, Gangming;  Hu, Xiaowei;  Li, Fei;  Gonzalez, Frank J.;  Liu, Aiming;  Yang, Julin
View  |  Adobe PDF(2087Kb)  |  Favorite  |  View/Download:66/7  |  Submit date:2018/05/08
Ppar Alpha  Nf-kappa b  Stat3  Alpha-naphthylisothiocyanate  Cholestasis  
Metabolic map of osthole and its effect on lipids 期刊论文
XENOBIOTICA, 2018, 卷号: 48, 期号: 3, 页码: 285-299
Authors:  Zhao, Qi;  Li, Xin-Mei;  Liu, Hong-Ning;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(2482Kb)  |  Favorite  |  View/Download:140/24  |  Submit date:2017/11/17
Lipid  Metabolomics  Metabolic Disease  Osthole  Time-of-flight Mass Spectrometry  Ultra-performance Liquid Chromatography  
Potential role of CYP1B1 in the development and treatment of metabolic diseases 期刊论文
PHARMACOLOGY & THERAPEUTICS, 2017, 卷号: 178, 页码: 18-30
Authors:  Li, Fei;  Zhu, Weifeng;  Gonzalez, Frank J.
View  |  Adobe PDF(2083Kb)  |  Favorite  |  View/Download:62/12  |  Submit date:2017/11/20
Cyp1b1  Metabolic Diseases  Metabolic Pathways  Metabolomics