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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice
期刊论文
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 1829
Authors:
Zhao,Qi
;
Dai,Man-Yun
;
Huang,Ruo-Yue
;
Duan,Jing-Yi
;
Zhang,Ting
;
Bao,Wei-Min
;
Zhang,Jing-Yi
;
Gui,Shao-Qiang
;
Xia,Shu-Min
;
Dai,Cong-Ting
;
Tang,Ying-Mei
;
Gonzalez,Frank J. J.
;
Li,Fei
View
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Submit date:2024/05/09
FATTY LIVER-DISEASE
INDUCED CHOLESTASIS
STELLATE CELLS
PROBIOTICS
PROTECTS
INFLAMMATION
APOPTOSIS
OBESITY
AXIS
雷公藤制剂对消化系统的毒性机理研究
学位论文
: 中国科学院大学, 2022
Authors:
代曼云
Adobe PDF(10574Kb)
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Submit date:2024/05/14
代谢组学,雷公藤,药源性肝损伤,消化性溃疡,FXR,ET-1, 肠道血管屏障
Metabolomics, Tripterygium wilfordii, Drug-induced liver injury, peptic ulcer disease, FXR, ET-1, intestinal vascular barrier.
Polyamine metabolism links gut microbiota and testicular dysfunction
期刊论文
MICROBIOME, 2021, 卷号: 9, 期号: 1, 页码: 224
Authors:
Zhao,Qi
;
Huang,Jian-Feng
;
Cheng,Yan
;
Dai,Man-Yun
;
Zhu,Wei-Feng
;
Yang,Xiu-Wei
;
Gonzalez,Frank J.
;
Li,Fei
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View/Download:183/0
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Submit date:2022/04/02
Testicular dysfunction
Gut microbiota
Polyamine metabolism
Metabolomics
SMALL-MOLECULE INHIBITOR
ORNITHINE-DECARBOXYLASE
TRIPTOLIDE
SPERMINE
ACTIVATION
DISRUPTION
MECHANISMS
EXPRESSION
APOPTOSIS
TRANSPORT
Discovery and validation of quality markers of Fructus Aurantii against acetylcholinesterase using metabolomics and bioactivity assays
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2021, 卷号: 44, 期号: 11, 页码: 2189-2205
Authors:
Wang,Yi-Kun
;
Zhou,Zi-Meng
;
Dai,Man-Yun
;
Ma,Xiao-Fang
;
Xiao,Xue-Rong
;
Zhang,Shou-Wen
;
Liu,Hong-Ning
;
Li,Fei
View
  |  
Adobe PDF(2083Kb)
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View/Download:260/77
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Submit date:2022/04/02
Fructus Aurantii
quality markers
metabolomics
serum pharmacochemistry
ultra high performance liquid chromatography
SERUM PHARMACOCHEMISTRY
RAT PLASMA
IDENTIFICATION
METABOLITES
IMMATURUS
COMPONENTS
EXTRACT
NEOHESPERIDIN
FINGERPRINT
NARINGIN
FXR activation prevents liver injury induced by Tripterygium wilfordii preparations
期刊论文
XENOBIOTICA, 2021, 卷号: 51, 期号: 6, 页码: 716-727
Authors:
Peng,Wan
;
Dai,Man-Yun
;
Bao,Li-Juan
;
Zhu,Wei-Feng
;
Li,Fei
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Adobe PDF(2010Kb)
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View/Download:258/55
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Submit date:2022/04/02
Tripterygium wilfordii
liver injury
farnesoid X receptor
bile acid metabolism
metabolomics
Discovery of quality markers in Rubus Chingii Hu using UPLC-ESI-QTOF-MS
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 203, 页码: 114200
Authors:
Zhou,Zi-Meng
;
Yan,Dong-Mei
;
Wang,Yi-Kun
;
Zhang,Ting
;
Xiao,Xue-Rong
;
Dai,Man-Yun
;
Zhang,Shou-Wen
;
Liu,Hong-Ning
;
Li,Fei
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View/Download:210/0
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Submit date:2022/04/02
Raspberry
Q-markers
Quality evaluation
UPLC-ESI-QTOF-MS
COMPONENTS
ACTIVATION
PATHWAY
FRUITS
Gut microbiota protects from triptolide-induced hepatotoxicity: Key role of propionate and its downstream signalling events
期刊论文
PHARMACOLOGICAL RESEARCH, 2020
Authors:
Huang, Jian-Feng
;
Zhao, Qi
;
Dai, Man-Yun
;
Xiao, Xue-Rong
;
Zhang, Ting
;
Zhu, Wei-Feng
;
Li, Fei
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Adobe PDF(3869Kb)
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View/Download:345/63
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Submit date:2021/01/05
Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1
期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
Authors:
Yang, Xiao-Nan
;
Wang, Yi-Kun
;
Zhu, Xu
;
Xiao, Xue-Rong
;
Dai, Man-Yun
;
Zhang, Ting
;
Qu, Yan
;
Yang, Xiu-Wei
;
Qin, Hong-Bo
;
Gonzalez, Frank J.
;
Li, Fei
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  |  
Adobe PDF(9057Kb)
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View/Download:445/74
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Submit date:2020/03/26
A phytochemical investigation of Stemona parviflora roots reveals several compounds with nematocidal activity
期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 159, 页码: 208-215
Authors:
Huang, Sheng-Zhuo
;
Kong, Fan-Dong
;
Chen, Gao
;
Cai, Xiang-Hai
;
Zhou, Li-Man
;
Ma, Qing-Yun
;
Wang, Qi
;
Mei, Wen-Li
;
Dai, Hao-Fu
;
Zhao, You-Xing
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Adobe PDF(614Kb)
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Submit date:2019/03/25
Stemona parviflora
Stemonaceae
Phenanthrene
Stilbene
Nematocidal activity