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Selective ERK1/2 agonists isolated from Melia azedarach with potent anti-leukemic activity 期刊论文
BMC Cancer, 2019, 卷号: 19, 期号: 1
Authors:  Wang,Ning;  Fan,Yanhua;  Yuan,Chun-Mao;  Song,Jialei;  Yao,Yao;  Liu,Wuling;  Gajendran,Babu;  Zacksenhaus,Eldad;  Li,Yanmei;  Liu,Jielin;  Hao,Xiao Jiang;  Ben-David,Yaacov
Favorite  |  View/Download:10/0  |  Submit date:2019/08/13
Cancer  Leukemia  Chinese medicinal plant  Melia azedarach  Drug screen  ERK1/2 agonists  Differentiation  Apoptosis  
A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice 期刊论文
XENOBIOTICA, 2019, 卷号: 49, 期号: 6, 页码: 655-670
Authors:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Liang, Wei-Qing;  Xiao, Yao;  Zhao, Qi;  Xiao, Xue-Rong;  Gonzalez, Frank J.;  Li, Fei
Favorite  |  View/Download:23/0  |  Submit date:2019/07/29
Pazopanib  hepatotoxicity  metabolomics  oxidative stress  ultra-performance liquid chromatography-electrospray ion source-quadrupole  time-of-flight mass spectrometer (UPLC-ESI-QTOFMS)  
Triterpenoids and Their Glycosides from Glinus Oppositifolius with Antifungal Activities against Microsporum Gypseum and Trichophyton Rubrum 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 12, 页码: 23
Authors:  Zhang, Dongdong;  Fu, Yao;  Yang, Jun;  Li, Xiao-Nian;  San, Myint Myint;  Oo, Thaung Naing;  Wang, Yuehu;  Yang, Xuefei
Favorite  |  View/Download:5/0  |  Submit date:2019/08/19
Glinus oppositifolius  triterpenoids and triterpenoid saponins  antifungal activity  
Progress in Understanding the Physiological and Molecular Responses of Populus to Salt Stress 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 卷号: 20, 期号: 6, 页码: 17
Authors:  Zhang, Xiaoning;  Liu, Lijun;  Chen, Bowen;  Qin, Zihai;  Xiao, Yufei;  Zhang, Ye;  Yao, Ruiling;  Liu, Hailong;  Yang, Hong
Favorite  |  View/Download:18/0  |  Submit date:2019/05/24
poplars (Populus)  salt tolerance  molecular mechanisms  SOS  ROS  
Identification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis 期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 11
Authors:  Liu, Tangjingjun;  Xia, Lei;  Yao, Yao;  Yan, Chen;  Fan, Yanhua;  Gajendran, Babu;  Yang, Jue;  Li, You-Jun;  Chen, Juan;  Filmus, Jorge;  Spaner, David E.;  Zacksenhaus, Eldad;  Hao, Xiaojiang;  Ben-David, Yaacov
Favorite  |  View/Download:112/0  |  Submit date:2019/04/15
Chemical constituents from the twigs and leaves of Trichilia sinensis and their biological activities 期刊论文
PHYTOCHEMISTRY LETTERS, 2019, 卷号: 29, 页码: 142-147
Authors:  Cao, Dong-Hua;  Sun, Peng;  Liao, Shang-Gao;  Gan, Li-She;  Yang, Lin;  Yao, Jian-Neng;  Zhang, Zong-Yi;  Li, Jin-Feng;  Zheng, Xiao-Ling;  Xiao, Yi-Dian;  Xiao, Chun-Fen;  Zhang, Ping;  Hu, Hua-Bin;  Xu, You-Kai
Favorite  |  View/Download:26/0  |  Submit date:2019/03/18
Trichina sinensis  Meliaceae  Mexicanolide-type limonoid  Phenolic acid  Anti-inflammatory activity  Antibacterial activity  
Synthesis of Fucosylated Chondroitin Sulfate Nonasaccharide as a Novel Anticoagulant Targeting Intrinsic Factor Xase Complex 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 卷号: 57, 期号: 39, 页码: 12880-12885
Authors:  Zhang, Xiao;  Liu, Huiying;  Lin, Lisha;  Yao, Wang;  Zhao, Jinhua;  Wu, Mingyi;  Li, Zhongjun
View  |  Adobe PDF(1568Kb)  |  Favorite  |  View/Download:87/12  |  Submit date:2018/10/22
Anticoagulants  Drug Discovery  Fucosylated Chondroitin Sulfate  Glycosaminoglycans  Oligosaccharides  
Synthesis of Fucosylated Chondroitin Sulfate Glycoclusters: A Robust Route to New Anticoagulant Agents 期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2018, 卷号: 24, 期号: 7, 页码: 1694-1700
Authors:  Zhang, Xiao;  Yao, Wang;  Xu, Xiaojiang;  Sun, Huifang;  Zhao, Jinhua;  Meng, Xiangbao;  Wu, Mingyi;  Li, Zhongjun
View  |  Adobe PDF(1719Kb)  |  Favorite  |  View/Download:51/5  |  Submit date:2018/05/08
Anticoagulants  Drug Discovery  Glycoconjugates  Structure-activity Relationships  Synthesis Design  
Isolation, identification and bioactivities of abietane diterpenoids from Premna szemaoensis 期刊论文
RSC ADVANCES, 2018, 卷号: 8, 期号: 12, 页码: 6425-6435
Authors:  Pu, De-Bing;  Wang, Ting;  Zhang, Xing-Jie;  Gao, Jun-Bo;  Zhang, Rui-Han;  Li, Xiao-Nian;  Wang, Yong-Mei;  Li, Xiao-Li;  Wang, He-Yao;  Xiao, Wei-Lie
Favorite  |  View/Download:17/0  |  Submit date:2018/05/08
Regioselective alkali metal reduction of dibenzocyclooctadiene lignan derivatives, demethoxylation followed by dehalogenation 期刊论文
Chemistry Central Journal, 2017, 卷号: 11, 期号: 1
Authors:  Wang,Qing-yao;  Fang,Jia-qi;  Deng,Lu-lu;  Hao,Xiao-jiang;  Mu,Shu-zhen
Favorite  |  View/Download:240/0  |  Submit date:2018/09/27
Alkali metal  Regioselective demethoxylation  Dehalogenation  Halogenated dibenzocyclooctadiene lignans  Aryl halides