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PXR mediates mifepristone-induced hepatomegaly in mice 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 1, 页码: 146-156
Authors:  Yao,Xin-peng;  Jiao,Ting-ying;  Jiang,Yi-ming;  Fan,Shi-cheng;  Zhao,Ying-yuan;  Yang,Xiao;  Gao,Yue;  Li,Fei;  Zhou,Yan-ying;  Chen,Pan-pan;  Huang,Min;  Bi,Hui-chang
Favorite  |  View/Download:89/0  |  Submit date:2022/04/02
mifepristone  hepatomegaly  pregnane X receptor (PXR)  yes-associated protein (YAP)  
Celastrol ameliorates acute liver injury through modulation of PPAR alpha 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020
Authors:  Zhao, Qi;  Tang, Ping;  Zhang, Ting;  Huang, Jian-Feng;  Xiao, Xue-Rong;  Zhu, Wei-Feng;  Gonzalez, Frank J.;  Li, Fei
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A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice 期刊论文
XENOBIOTICA, 2019, 卷号: 49, 期号: 6, 页码: 655-670
Authors:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Liang, Wei-Qing;  Xiao, Yao;  Zhao, Qi;  Xiao, Xue-Rong;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(1101Kb)  |  Favorite  |  View/Download:251/107  |  Submit date:2019/07/29
Pazopanib  hepatotoxicity  metabolomics  oxidative stress  ultra-performance liquid chromatography-electrospray ion source-quadrupole  time-of-flight mass spectrometer (UPLC-ESI-QTOFMS)  
胆汁淤积性肝损伤的药物治疗研究 学位论文
博士: 中国科学院昆明植物研究所, 2019
Authors:  赵琦
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非诺贝特  雷公藤红素  胆汁淤积  肝纤维化  代谢组学  
Celastrol Protects From Cholestatic Liver Injury Through Modulation of SIRT1-FXR Signaling 期刊论文
MOLECULAR & CELLULAR PROTEOMICS, 2019, 卷号: 18, 期号: 3, 页码: 520-533
Authors:  Zhao, Qi;  Liu, Fang;  Cheng, Yan;  Xiao, Xue-Rong;  Hu, Dan-Dan;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(4782Kb)  |  Favorite  |  View/Download:176/60  |  Submit date:2019/07/29
胆汁淤积性肝损伤的代谢组学研究 学位论文
硕士, 2018
Authors:  杨锐
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PPAR alpha activation protects against cholestatic liver injury 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 9967
Authors:  Zhao, Qi;  Yang, Rui;  Wang, Jing;  Hu, Dan-Dan;  Li, Fei
View  |  Adobe PDF(7693Kb)  |  Favorite  |  View/Download:238/54  |  Submit date:2017/10/23
Primary Biliary-cirrhosis  Bile-acid Homeostasis  Receptor-alpha  Ursodeoxycholic Acid  Cholesterol 7-alpha-hydroxylase  Beta-oxidation  Fenofibrate  Therapy  Mice  Hepatotoxicity  
retraction :Metabolomics reveals that PPAR alpha activation protects against lithocholic acid-induced liver injury 期刊论文
RSC ADVANCES, 2017, 卷号: 7, 期号: 79, 页码: 49849-49857
Authors:  Zhao, Qi;  Yang, Rui;  Liu, Fang;  Wang, Jing;  Hu, Dan-Dan;  Yang, Xiu-Wei;  Li, Fei
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Protective effects of triterpenoids from Ganoderma resinaceum on H2O2-induced toxicity in HepG2 cells 期刊论文
FOOD CHEMISTRY, 2013, 卷号: 141, 期号: 2, 页码: 920-926
Authors:  Peng, Xing-Rong;  Liu, Jie-Qing;  Han, Zhong-Hui;  Yuan, Xiao-Xi;  Luo, Huai-Rong;  Qiu, Ming-Hua
View  |  Adobe PDF(375Kb)  |  Favorite  |  View/Download:575/131  |  Submit date:2013/10/16
Ganoderma Resinaceum  Ganoderma Triterpenoids  Hepatoprotective Activities  Cyp3a4  Hepg2 Cells  
Isolation and Bioactivity Evaluation of Terpenoids from the Medicinal Fungus Ganoderma sinense 期刊论文
PLANTA MEDICA, 2012, 卷号: 78, 期号: 4, 页码: 368-376
Authors:  Liu, Jie-Qing;  Wang, Cui-Fang;  Li, Yan;  Luo, Huai-Rong;  Qiu, Ming-Hua
View  |  Adobe PDF(210Kb)  |  Favorite  |  View/Download:292/115  |  Submit date:2015/06/17
Ganoderma Sinense  Ganodermataceae  Triterpenoids  Sesquiterpene  Cytotoxicity  Cyp3a4 Induction