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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1
期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
Authors:
Jingru Li
;
Yicheng Chen
;
Jiali Wan
;
Xin Liu
;
Chunrong Yu
;
Wenhua Li
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Submit date:2017/07/24
Abt-263
Sorafenib
Combination Therapy
Cancer
Glabridin inhibits migration and invasion by transcriptional inhibition of matrix metalloproteinase-9 through modulation of NF-B and AP-1 activity in human liver cancer cells lines
期刊论文
出版物, 3111, 期号: 0, 页码: 1—28
Authors:
Ming-Ju Hsieh
;
Chiao-Wen Lin
;
Shun-Fa Yang
;
Mu-Kuan Chen
;
Hui-Ling Chiou
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Submit date:2017/07/24
Glabridin
Migration
Invasion
Matrix Metalloproteinase-9
Hepatoma
Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress
期刊论文
PHYTOMEDICINE, 2023, 卷号: 112, 页码: 154720
Authors:
Niu,Zhenpeng
;
Tang,Guihua
;
Wang,Xuenan
;
Yang,Xu
;
Zhao,Yueqin
;
Wang,Yinyuan
;
Liu,Qin
;
Zhang,Fan
;
Zhao,Yuhan
;
Ding,Xiao
;
Hao,Xiaojiang
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Submit date:2024/07/17
Lysosomal biogenesis
Autophagy
TFEB
TFE3
ER stress
IVDD
STAT3
TFE3
Ganoapplins A and B with an unprecedented 6/6/6/5/6-fused pentacyclic skeleton from Ganoderma inhibit Tau pathology through activating autophagy
期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 132, 页码: 106375
Authors:
Peng,Xingrong
;
Luo,Rongcan
;
Ran,Xiaoqian
;
Guo,Yarong
;
Yao,Yong-Gang
;
Qiu,Minghua
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Submit date:2024/07/22
Ganoderma
Ganoderma applanatum
Triterpenoid
Autophagy
Tau pathology
Alzheimer?s disease
LANOSTANE-TYPE TRITERPENOIDS
ALZHEIMERS-DISEASE
FRUITING BODIES
NEURODEGENERATION
ACID
Sesquiterpenes from Carpesium faberi triggered ROS-induced apoptosis and protective autophagy in hepatocellular carcinoma cells
期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 214, 页码: 113805
Authors:
Yan,Ying
;
Chen,Jie
;
Peng,Mingyou
;
Zhang,Xiong
;
Feng,Enming
;
Li,Qindan
;
Guo,Bing
;
Ding,Xiao
;
Zhang,Yu
;
Tang,Lei
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Submit date:2024/07/25
Carpesium faberi (compositae)
Sesquiterpenes
Structural elucidation
Cytotoxic activities
Autophagy
LACTONE DIMERS
MYRRHANONE C
XANTHANOLIDES
TRITERPENE
HYBRIDS
ESTERS
Munronin V with 7/7/6 tricarbocyclic framework from Munronia henryi harms inhibits tau pathology by activating autophagy
期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 卷号: 21, 期号: 3, 页码: 514-519
Authors:
Yan,Ying
;
Ran,Xiaoqian
;
Wang,Dan
;
Zhang,Xiong
;
Peng,Mingyou
;
Yan,Xiaoyan
;
Tang,Lei
;
Liang,Hong
;
Qin,Xujie
;
Di,Ying-Tong
;
Luo,Rongcan
;
Hao,Xiao-Jiang
;
Yao,Yong-Gang
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Submit date:2024/07/25
UBIQUITIN-PROTEASOME SYSTEM
ALZHEIMERS-DISEASE
CONSTITUENTS
LIMONOIDS
TFEB
NEURODEGENERATION
Tripterygium wilfordii protects against an animal model of autoimmune hepatitis
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 309, 页码: 116365
Authors:
Zhang,Ting
;
Rao,Qianru
;
Dai,Manyun
;
Zhao,Qi
;
Li,Fei
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Submit date:2024/07/25
Tripterygium wilfordii tablets
Celastrol
Concanavalin A
Autophagy
TFEB
PXR
PREGNANE-X-RECEPTOR
CHOLESTATIC LIVER-INJURY
CELASTROL PROTECTS
AUTOPHAGY
OBESITY
DYSFUNCTION
DOMAIN
New Monoterpenoid Indole Alkaloids from Tabernaemontana crassa Inhibit beta-Amyloid42 Production and Phospho-Tau (Thr217)
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2, 页码: 1487
Authors:
Li,Sheng
;
Han,Ling-Ling
;
Huang,Ke-Pu
;
Ma,Ye-Han
;
Guo,Ling-Li
;
Guo,Yarong
;
Ran,Xiaoqian
;
Yao,Yong-Gang
;
Hao,Xiao-Jiang
;
Luo,Rongcan
;
Zhang,Yu
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Submit date:2024/05/09
Tabernaemontana crassa
monoterpenoid indole alkaloids
A beta 42
phospho-tau (Thr217)
Alzheimer's disease
ALZHEIMERS-DISEASE
BISINDOLE ALKALOIDS
CDK5
GEMFIBROZIL
PREVENTION
ALGORITHM
AUTOPHAGY
MODELS
PLANTS
MOUSE
Jatrophane Diterpenoids from Euphorbia peplus Linn. as Activators of Autophagy and Inhibitors of Tau Pathology
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2, 页码: 1088
Authors:
Yan,Ying
;
Zhou,Qi
;
Ran,Xiaoqian
;
Lu,Qingyun
;
Zhang,Cuishan
;
Peng,Mingyou
;
Tang,Lei
;
Luo,Rongcan
;
Di,Yingtong
;
Hao,Xiaojiang
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Submit date:2024/05/09
euphjatrophane
Euphorbia peplus
jatrophane diterpenoid
autophagy
Tau pathology
UBIQUITIN-PROTEASOME SYSTEM
MULTIDRUG-RESISTANCE
BIOLOGICAL-ACTIVITY
ALZHEIMERS-DISEASE
MODULATORS
CELLS
Euphejolkinolide A, a new ent-abietane lactone from Euphorbia peplus L. with promising biological activity in activating the autophagy-lysosomal pathway
期刊论文
HELIYON, 2023, 卷号: 9, 期号: 2, 页码: e13691
Authors:
Ran,Xiaoqian
;
Lu,Qing-Yun
;
Li,Ying-Yao
;
Pu,Xue-Xue
;
Guo,Yarong
;
Yuan,Ming-Rui
;
Guan,Shi-Peng
;
Sun,Mao
;
Jiao,Lijin
;
Yao,Yong-Gang
;
Di,Ying-Tong
;
Hao,Xiao-Jiang
;
Luo,Rongcan
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Submit date:2024/07/30
Euphorbia peplus L
Euphorbiaceae
Ent-abietane diterpenoid
Euphejolkinolide A
Autophagy-lysosomal pathway
ALZHEIMERS-DISEASE
TAU PATHOLOGY
NEURODEGENERATION
DITERPENOIDS
INHIBITION
MECHANISMS
APOPTOSIS
CELASTROL
PROTEIN
SYSTEM