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Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress 期刊论文
PHYTOMEDICINE, 2023, 卷号: 112, 页码: 154720
Authors:  Niu,Zhenpeng;  Tang,Guihua;  Wang,Xuenan;  Yang,Xu;  Zhao,Yueqin;  Wang,Yinyuan;  Liu,Qin;  Zhang,Fan;  Zhao,Yuhan;  Ding,Xiao;  Hao,Xiaojiang
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Lysosomal biogenesis  Autophagy  TFEB  TFE3  ER stress  IVDD  STAT3  TFE3  
Tripterygium wilfordii protects against an animal model of autoimmune hepatitis 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 309, 页码: 116365
Authors:  Zhang,Ting;  Rao,Qianru;  Dai,Manyun;  Zhao,Qi;  Li,Fei
View  |  Adobe PDF(13950Kb)  |  Favorite  |  View/Download：53/16  |  Submit date：2024/07/25
Tripterygium wilfordii tablets  Celastrol  Concanavalin A  Autophagy  TFEB  PXR  PREGNANE-X-RECEPTOR  CHOLESTATIC LIVER-INJURY  CELASTROL PROTECTS  AUTOPHAGY  OBESITY  DYSFUNCTION  DOMAIN  
Euphejolkinolide A, a new ent-abietane lactone from Euphorbia peplus L. with promising biological activity in activating the autophagy-lysosomal pathway 期刊论文
HELIYON, 2023, 卷号: 9, 期号: 2, 页码: e13691
Authors:  Ran,Xiaoqian;  Lu,Qing-Yun;  Li,Ying-Yao;  Pu,Xue-Xue;  Guo,Yarong;  Yuan,Ming-Rui;  Guan,Shi-Peng;  Sun,Mao;  Jiao,Lijin;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang;  Luo,Rongcan
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Euphorbia peplus L  Euphorbiaceae  Ent-abietane diterpenoid  Euphejolkinolide A  Autophagy-lysosomal pathway  ALZHEIMERS-DISEASE  TAU PATHOLOGY  NEURODEGENERATION  DITERPENOIDS  INHIBITION  MECHANISMS  APOPTOSIS  CELASTROL  PROTEIN  SYSTEM  
Iridoid glycosides from Morinda officinalis induce lysosomal biogenesis and promote autophagic flux to attenuate oxidative stress 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2023
Authors:  Wang,Yin-Yuan;  Ni,Jian-Cheng;  Zhao,Yue-Qin;  Yang,Xu;  Niu,Zhen-Peng;  Yang,Xing-Zhi;  Dong,Xian-Xiang;  Zhao,Yu-Han;  Hao,Xiao-Jiang;  Ding,Xiao
View  |  Adobe PDF(1997Kb)  |  Favorite  |  View/Download：54/10  |  Submit date：2024/07/31
Iridoid glycosides  Morinda officinalis  lysosomal biogenesis  TFEB/TFE3  antioxidant activity  TRANSCRIPTIONAL CONTROL  TFEB  PHOSPHORYLATION  REVEALS  PATHWAY  
蕊木和奶子藤中生物碱类化学成分及其生物活性评价 学位论文
: 中国科学院大学, 2022
Authors:  陈谌
Adobe PDF(17478Kb)  |  Favorite  |  View/Download：386/0  |  Submit date：2024/05/14
夹竹桃科  Apocynaceae  蕊木  Kopsia arborea  奶子藤  Bousigonia mekongensis  单萜吲哚生物碱  Monoterterpene indole alkaloids  生物活性  Biological activity  
南欧大戟中大戟二萜类成分及其自噬相关活性评价 学位论文
: 中国科学院大学, 2022
Authors:  李盈瑶
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南欧大戟  Euphorbia peplus  大戟二萜  Euphorbia diterpenoids  自噬-溶酶体  autophagy-lysosomal  
新型天然铁死亡诱导剂的筛选及作用机制研究 学位论文
: 中国科学院大学, 2022
Authors:  赵越勤
Adobe PDF(5494Kb)  |  Favorite  |  View/Download：64/0  |  Submit date：2024/05/14
肿瘤，天然产物，铁死亡，溶酶体，p53  Cancer, Nature products, Ferroptosis, Lysosome, p53  
Novel Signature Genes and Pathways Identified for Human Left Ventricle Cardiomyopathies Rise from different Etiologies 期刊论文
Journal of Biomedical Research and Reviews, 2021
Authors:  Jiao Tian;  Zheng Yuan Wu;  Ying Ying He;  Shubai Liu
View  |  Adobe PDF(1819Kb)  |  Favorite  |  View/Download：105/31  |  Submit date：2023/09/08
Diterpenoids with an unprecedented ring system from Euphorbia peplus and their activities in the lysosomal-autophagy pathway 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 7, 页码: 1541-1545
Authors:  Chen,Yan-Ni;  Ding,Xiao;  Li,Dong-Mei;  Sun,Mao;  Yang,Lei;  Zhang,Yu;  Di,Ying-Tong;  Fang,Xin;  Hao,Xiao-Jiang
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Harpertrioate A, an A,B,D-seco-Limonoid with Promising Biological Activity against Alzheimer's Disease from Twigs of Harrisonia perforata (Blanco) Merr 期刊论文
ORGANIC LETTERS, 2021
Authors:  Tang,Xiao-Han;  Luo,Rong-Can;  Ye,Mao-Sen;  Tang,Hong-Yu;  Ma,Yuan-Liang;  Chen,Yan-Ni;  Wang,Xin-Meng;  Lu,Qing-Yun;  Liu,Shuai;  Li,Xiao-Nian;  Yan,Ying;  Yang,Jing;  Ran,Xiao-Qian;  Fang,Xin;  Zhou,Yan;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang
View  |  Adobe PDF(2579Kb)  |  Favorite  |  View/Download：239/70  |  Submit date：2023/09/08