Diterpenoids with an unprecedented ring system from Euphorbia peplus and their activities in the lysosomal-autophagy pathway

doi:10.1039/d0ob02414g

KIB OpenIR

	Diterpenoids with an unprecedented ring system from Euphorbia peplus and their activities in the lysosomal-autophagy pathway
	Chen,Yan-Ni ; Ding,Xiao ; Li,Dong-Mei ; Sun,Mao ; Yang,Lei ; Zhang,Yu; Di,Ying-Tong ; Fang,Xin ; Hao,Xiao-Jiang
	2021
Source Publication	ORGANIC & BIOMOLECULAR CHEMISTRY
ISSN	1477-0520
Volume	19 Issue:7 Pages:1541-1545
Abstract	Three novel jatrophane diterpenes, cyclojatrophanes A-C (1-3), were isolated from the seeds of Euphorbia peplus. Compounds 1-3 featured an unprecedented 5/5/5/11 tetracyclic ring system incorporating ditetrahydropyran rings. Their structures including their absolute configurations were established by extensive spectroscopic analysis, X-ray crystallographic experiments and chemical transformations. In addition, these compounds could significantly activate the lysosomal-autophagy pathway.
DOI	10.1039/d0ob02414g
WOS ID	WOS:000621563000010
Citation statistics	Cited Times:10[WOS] [WOS Record] [Related Records in WOS]
Document Type	期刊论文
Identifier	http://ir.kib.ac.cn/handle/151853/73695
Collection	中国科学院昆明植物研究所
Affiliation	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming, Yunnan, Peoples R China 2.Shanghai Chenshan Bot Garden, Shanghai Key Lab Plant Funct Genom & Resource, Plant Sci Res Ctr, Shanghai, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Yunnan Univ, Kunming, Yunnan, Peoples R China
Recommended Citation GB/T 7714	Chen,Yan-Ni,Ding,Xiao,Li,Dong-Mei,et al. Diterpenoids with an unprecedented ring system from Euphorbia peplus and their activities in the lysosomal-autophagy pathway[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2021,19(7):1541-1545.
APA	Chen,Yan-Ni.,Ding,Xiao.,Li,Dong-Mei.,Sun,Mao.,Yang,Lei.,...&Hao,Xiao-Jiang.(2021).Diterpenoids with an unprecedented ring system from Euphorbia peplus and their activities in the lysosomal-autophagy pathway.ORGANIC & BIOMOLECULAR CHEMISTRY,19(7),1541-1545.
MLA	Chen,Yan-Ni,et al."Diterpenoids with an unprecedented ring system from Euphorbia peplus and their activities in the lysosomal-autophagy pathway".ORGANIC & BIOMOLECULAR CHEMISTRY 19.7(2021):1541-1545.

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