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Anti-arthritis effects of (E)-2,4-bis(p-hydroxyphenyl)-2-butenal through inhibition of STAT3 pathway 期刊论文
出版物, 3111, 期号: 0, 页码: 1-50
Authors:  Jung Ok Ban;  Dae Hwan Kim;  Hee Pom Lee;  Chul Ju Hwang;  Jung-Hyun Shim;  Dae Joong Kim;  Tae Myoung Kim;  Heon Sang Jeong;  Seong Su Nah;  Hanyong Chen;  Zigang Dong;  Young Wan Ham;  Youngsoo Kim;  Sang-Bae Han;  Jin Tae Hong
Adobe PDF(1327Kb)  |  Favorite  |  View/Download：333/3  |  Submit date：2017/07/24
ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
Authors:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
Adobe PDF(1198Kb)  |  Favorite  |  View/Download：348/1  |  Submit date：2017/07/24
Abt-263  Sorafenib  Combination Therapy  Cancer  
YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK 期刊论文
出版物, 3111, 期号: 0, 页码: 1-46
Authors:  Ling-Chu Chang;  Hui-Yi Lin;  Meng-Tung Tsai;  Ruey-Hwang Chou;  Fang-Yu Lee;  Che-Ming Teng;  Min-Tsang Hsieh;  Hsin-Yi Hung;  Li-Jiau Huang;  Yung-Luen Yu;  Sheng-Chu Kuo
Adobe PDF(1357Kb)  |  Favorite  |  View/Download：498/1  |  Submit date：2017/07/24
Yc-1  Triple-negative Breast Cancer  Erk  Ezh2  C-cbl  
Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress 期刊论文
PHYTOMEDICINE, 2023, 卷号: 112, 页码: 154720
Authors:  Niu,Zhenpeng;  Tang,Guihua;  Wang,Xuenan;  Yang,Xu;  Zhao,Yueqin;  Wang,Yinyuan;  Liu,Qin;  Zhang,Fan;  Zhao,Yuhan;  Ding,Xiao;  Hao,Xiaojiang
View  |  Adobe PDF(11543Kb)  |  Favorite  |  View/Download：194/31  |  Submit date：2024/07/17
Lysosomal biogenesis  Autophagy  TFEB  TFE3  ER stress  IVDD  STAT3  TFE3  
RUNX1-Regulated Signaling Pathways in Ovarian Cancer 期刊论文
BIOMEDICINES, 2023, 卷号: 11, 期号: 9, 页码: 2357
Authors:  Chen,Yuanzhi;  He,Yingying;  Liu,Shubai
View  |  Adobe PDF(1447Kb)  |  Favorite  |  View/Download：202/32  |  Submit date：2024/05/09
Runt-related transcription factor 1 (RUNX1)  ovarian cancer  apoptosis  signaling pathways  clinical therapeutic target  GROWTH-FACTOR  TRANSCRIPTION FACTORS  STEM-CELLS  RUNX1  STAT3  FAMILY  ACTIVATION  APOPTOSIS  LEUKEMIA  SURVIVAL  
Cytostatic Activity of Sanguinarine and a Cyanide Derivative in Human Erythroleukemia Cells Is Mediated by Suppression of c-MET/MAPK Signaling 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 9, 页码: 8113
Authors:  Xu,Xinglian;  Deng,Lulu;  Tang,Yaling;  Li,Jiang;  Zhong,Ting;  Hao,Xiaojiang;  Fan,Yanhua;  Mu,Shuzhen
View  |  Adobe PDF(5829Kb)  |  Favorite  |  View/Download：208/25  |  Submit date：2024/05/09
leukemia  sanguinarine  c-MET  MAPK  PI3K/mTOR  STAT3  MET  
皱叶酸模根的化学成分及生物活性研究 学位论文
: 中国科学院大学, 2022
Authors:  李永祥
Adobe PDF(4646Kb)  |  Favorite  |  View/Download：118/0  |  Submit date：2024/05/14
皱叶酸模，化学成分，生物活性，网络药理学  Rumex crispus L., Chemical composition, Biological activity, Network pharmacology  
Anticarin-beta shows a promising anti-osteosarcoma effect by specifically inhibiting CCT4 to impair proteostasis 期刊论文
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 5, 页码: 2268-2279
Authors:  Wang, Gan;  Zhang, Min;  Meng, Ping;  Long, Chengbo;  Luo, Xiaodong;  Yang, Xingwei;  Wang, Yunfei;  Zhang, Zhiye;  Mwangi, James;  Kamau, Peter Muiruri;  Dai, Zhi;  Ke, Zunfu;  Zhang, Yi;  Chen, Wenlin;  Zhao, Xudong;  Ge, Fei;  Lv, Qiumin;  Rong, Mingqiang;  Li, Dongsheng;  Jin, Yang;  Sheng, Xia;  Lai, Ren
View  |  Adobe PDF(4759Kb)  |  Favorite  |  View/Download：219/43  |  Submit date：2024/04/30
Proteostasis  CCT  TRiC  Osteosarcoma  STAT3  Anticarin-beta  PDX model  CYTOSOLIC CHAPERONIN  CANCER-CELLS  COMPLEX  EXPRESSION  SURVIVAL  PROTEIN  TUBULIN  GROWTH  
Polysaccharide Peptide Induced Colorectal Cancer Cells Apoptosis by Down-Regulating EGFR and PD-L1 Expression 期刊论文
IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH, 2022, 卷号: 21, 期号: 1, 页码: e123909
Authors:  Lin Jian;  He Zhicheng;  Liu Shubai
View  |  Adobe PDF(3879Kb)  |  Favorite  |  View/Download：113/11  |  Submit date：2024/08/21
Colorectal Cancer  Trametes Versicolor  EGFR  PD-L1  Polysaccharide Peptide  CORIOLUS-VERSICOLOR  SIGNALING PATHWAY  COLON-CANCER  T-CELLS  STATISTICS  THERAPY  
雷公藤制剂肝毒性的机制及其调节作用研究 学位论文
, 2021
Authors:  彭婉
Adobe PDF(6945Kb)  |  Favorite  |  View/Download：81/0  |  Submit date：2024/03/20