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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
Authors:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
Adobe PDF(1403Kb)  |  Favorite  |  View/Download:104/1  |  Submit date:2017/07/24
Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
Authors:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
Adobe PDF(1198Kb)  |  Favorite  |  View/Download:15/1  |  Submit date:2017/07/24
Abt-263  Sorafenib  Combination Therapy  Cancer  
Spirocyclic polycyclic polyprenylated acylphloroglucinols from the ethyl acetate fraction of Hypericum henryi 期刊论文
TETRAHEDRON LETTERS, 2018, 卷号: 59, 期号: 46, 页码: 4067-4072
Authors:  Duan, Yao-Tao;  Zhang, Juan;  Lao, Yuan-Zhi;  Tan, Hong-Sheng;  Ye, Yan-Song;  Yang, Xing-Wei;  Xu, Hong-Xi;  Xu, Gang
View  |  Adobe PDF(895Kb)  |  Favorite  |  View/Download:350/80  |  Submit date:2018/12/18
Polyprenylated Acylphloroglucinol  Hyperhenones G-m  Hypericum Henryi  Spirocyclic  Antitumor  
Virtual screening of B-Raf kinase inhibitors: A combination of pharmacophore modelling, molecular docking, 3D-QSAR model and binding free energy calculation studies 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2017, 卷号: 70, 页码: 186-190
Authors:  Zhang, Wen;  Qiu, Kai-Xiong;  Yu, Fang;  Xie, Xiao-Guang;  Zhang, Shu-Qun;  Chen, Ya-Juan;  Xie, Hui-Ding
View  |  Adobe PDF(371Kb)  |  Favorite  |  View/Download:47/2  |  Submit date:2017/12/11
B-raf Kinase Inhibitors  Virtual Screening  Pharmacophore  Molecular Docking  3d Qsar  Binding Free Energy Calculation  
三种马鞭草科植物和有柄树舌萜类化学成分及生物活性研究 学位论文
: 中国科学院大学, 2017
Authors:  普德兵
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USP7 作为结直肠肿瘤治疗靶点的研究 学位论文
: 中国科学院大学, 2017
Authors:  安涛
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Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 50, 页码: 82820-82835
Authors:  Zhou, Xunian;  Yue, Grace Gar-Lee;  Liu, Minghua;  Zuo, Zhili;  Lee, Julia Kin-Ming;  Li, Mingyue;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Sun, Handong;  Pu, Jianxin;  Lau, Clara Bik-San
View  |  Adobe PDF(13632Kb)  |  Favorite  |  View/Download:133/7  |  Submit date:2017/02/28
Eriocalyxin b  Angiogenesis  Vascular Endothelial Growth Factor (Vegf)  Vascular Endothelial Growth Factor Receptor 2(Vegfr-2)  Breast Cancer  
New potential beneficial effects of actein, a triterpene glycoside isolated from Cimicifuga species, in breast cancer treatment 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 期号: 1, 页码: 1
Authors:  Yue, Grace Gar-Lee;  Xie, Sida;  Lee, Julia Kin-Ming;  Kwok, Hin-Fai;  Gao, Si;  Nian, Yin;  Wu, Xiao-Xiao;  Wong, Chun-Kwok;  Qiu, Ming-Hua;  Lau, Clara Bik-San
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疏花毛萼香茶菜中两株内生真菌的次生代谢产物研究 学位论文
: 中国科学院大学, 2016
Authors:  唐健维
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Grifolin directly targets ERK1/2 to epigenetically suppress cancer cell metastasis 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 40, 页码: 42704-42716
Authors:  Luo, Xiangjian;  Yang, Lifang;  Xiao, Lanbo;  Xia, Xiaofeng;  Dong, Xin;  Zhong, Juanfang;  Liu, Ying;  Li, Namei;  Chen, Ling;  Li, Hongde;  Li, Wei;  Liu, Wenbin;  Yu, Xinfang;  Chen, Hanyong;  Tang, Min;  Weng, Xinxian;  Yi, Wei;  Bode, Ann;  Dong, Zigang;  Liu, Jikai;  Cao, Ya
View  |  Adobe PDF(5262Kb)  |  Favorite  |  View/Download:103/3  |  Submit date:2016/06/27
Grifolin  Erk1/2  Dnmt1  Metastasis