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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
Authors:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
Adobe PDF(1403Kb)  |  Favorite  |  View/Download：451/1  |  Submit date：2017/07/24
Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1 期刊论文
出版物, 2111, 页码: 1-44
Authors:  1M S Grace;  T Lieu;  B Darby;  F C Abogadie;  N Veldhuis N W Bunnett;  P McIntyre
Adobe PDF(1611Kb)  |  Favorite  |  View/Download：345/1  |  Submit date：2017/07/24
Transient Receptor Potential Ion Channel  Trpv4  Protease Activated Receptor  Par2  Pain  Tyrosine Kinase  Bafetinib  
Tripterygium wilfordii protects against an animal model of autoimmune hepatitis 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 309, 页码: 116365
Authors:  Zhang,Ting;  Rao,Qianru;  Dai,Manyun;  Zhao,Qi;  Li,Fei
View  |  Adobe PDF(13950Kb)  |  Favorite  |  View/Download：171/39  |  Submit date：2024/07/25
Tripterygium wilfordii tablets  Celastrol  Concanavalin A  Autophagy  TFEB  PXR  PREGNANE-X-RECEPTOR  CHOLESTATIC LIVER-INJURY  CELASTROL PROTECTS  AUTOPHAGY  OBESITY  DYSFUNCTION  DOMAIN  
Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice 期刊论文
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 1829
Authors:  Zhao,Qi;  Dai,Man-Yun;  Huang,Ruo-Yue;  Duan,Jing-Yi;  Zhang,Ting;  Bao,Wei-Min;  Zhang,Jing-Yi;  Gui,Shao-Qiang;  Xia,Shu-Min;  Dai,Cong-Ting;  Tang,Ying-Mei;  Gonzalez,Frank J. J.;  Li,Fei
View  |  Adobe PDF(5393Kb)  |  Favorite  |  View/Download：246/44  |  Submit date：2024/05/09
FATTY LIVER-DISEASE  INDUCED CHOLESTASIS  STELLATE CELLS  PROBIOTICS  PROTECTS  INFLAMMATION  APOPTOSIS  OBESITY  AXIS  
Hepatic RACK1 deletion disturbs lipid and glucose homeostasis independently of insulin resistance 期刊论文
JOURNAL OF ENDOCRINOLOGY, 2022, 卷号: 254, 期号: 3, 页码: 151-165
Authors:  Qin, Wanying;  Zhang, Ting;  Ge, Mingxia;  Zhou, Huimin;  Xu, Yuhui;  Mu, Rongfang;  Huang, Chaoguang;  Liu, Daowei;  Huang, Bangrui;  Wang, Qian;  Kong, Qinghua;  Kong, Qingpeng;  Li, Fei;  Xiong, Wenyong
View  |  Adobe PDF(9525Kb)  |  Favorite  |  View/Download：218/28  |  Submit date：2024/04/30
RACK1  bile acid  glucose metabolism  insulin sensitivity  ENDOPLASMIC-RETICULUM STRESS  C-KINASE 1  HEPATOCELLULAR-CARCINOMA  STEROL 12-ALPHA-HYDROXYLASE  DOWN-REGULATION  ER STRESS  KAPPA-B  RECEPTOR  ACTIVATION  GROWTH  
雷公藤制剂肝毒性的机制及其调节作用研究 学位论文
, 2021
Authors:  彭婉
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Artemicapillasins A-N, cytotoxic coumaric acid analogues against hepatic stellate cell LX2 from Artemisia capillaris (Yin-Chen) 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 117, 页码: 105441
Authors:  Gao,Zhen;  Huang,Xiao-Yan;  Geng,Chang-An;  Li,Tian-Ze;  Chen,Ji-Jun
View  |  Adobe PDF(1872Kb)  |  Favorite  |  View/Download：312/89  |  Submit date：2022/04/02
Artemisia capillaris  Coumaric acid analogues  Antihepatic fibrosis effects  HSC-LX2  Extracellular matrix  TRADITIONAL CHINESE HERB  ACTIVE CONSTITUENTS  LIVER FIBROSIS  
FXR activation prevents liver injury induced by Tripterygium wilfordii preparations 期刊论文
XENOBIOTICA, 2021, 卷号: 51, 期号: 6, 页码: 716-727
Authors:  Peng,Wan;  Dai,Man-Yun;  Bao,Li-Juan;  Zhu,Wei-Feng;  Li,Fei
View  |  Adobe PDF(2010Kb)  |  Favorite  |  View/Download：261/55  |  Submit date：2022/04/02
Tripterygium wilfordii  liver injury  farnesoid X receptor  bile acid metabolism  metabolomics  
Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963
Authors:  Liu,Jiangxin;  Wu,Xing-De;  Li,Wenyan;  Yuan,Zaifeng;  Yang,Kun;  Zhao,Qin-Shi
View  |  Adobe PDF(3665Kb)  |  Favorite  |  View/Download：230/49  |  Submit date：2022/04/02
Pseudolaric acid A  Hsp90 inhibitor  Apoptosis  NMR  Structure-activity relationship  Photoaffinity-based probe  Protein-ligand interaction  MOLECULAR CHAPERONE  PROTEIN  TARGET  CANCER  KINASE  NMR  IDENTIFICATION  SELECTIVITY  BINDING  DESIGN  
茵陈蒿的化学成分及其代谢研究 学位论文
, 2020
Authors:  肖瑶
Adobe PDF(9556Kb)  |  Favorite  |  View/Download：113/0  |  Submit date：2023/11/02