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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
Authors:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
Adobe PDF(1403Kb)  |  Favorite  |  View/Download:202/1  |  Submit date:2017/07/24
Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1 期刊论文
出版物, 2111, 页码: 1-44
Authors:  1M S Grace;  T Lieu;  B Darby;  F C Abogadie;  N Veldhuis N W Bunnett;  P McIntyre
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Transient Receptor Potential Ion Channel  Trpv4  Protease Activated Receptor  Par2  Pain  Tyrosine Kinase  Bafetinib  
Artemicapillasins A-N, cytotoxic coumaric acid analogues against hepatic stellate cell LX2 from Artemisia capillaris (Yin-Chen) 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 117, 页码: 105441
Authors:  Gao,Zhen;  Huang,Xiao-Yan;  Geng,Chang-An;  Li,Tian-Ze;  Chen,Ji-Jun
Adobe PDF(1872Kb)  |  Favorite  |  View/Download:13/0  |  Submit date:2022/04/02
Artemisia capillaris  Coumaric acid analogues  Antihepatic fibrosis effects  HSC-LX2  Extracellular matrix  TRADITIONAL CHINESE HERB  ACTIVE CONSTITUENTS  LIVER FIBROSIS  
FXR activation prevents liver injury induced by Tripterygium wilfordii preparations 期刊论文
XENOBIOTICA, 2021, 卷号: 51, 期号: 6, 页码: 716-727
Authors:  Peng,Wan;  Dai,Man-Yun;  Bao,Li-Juan;  Zhu,Wei-Feng;  Li,Fei
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Tripterygium wilfordii  liver injury  farnesoid X receptor  bile acid metabolism  metabolomics  
Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963
Authors:  Liu,Jiangxin;  Wu,Xing-De;  Li,Wenyan;  Yuan,Zaifeng;  Yang,Kun;  Zhao,Qin-Shi
Adobe PDF(3665Kb)  |  Favorite  |  View/Download:19/0  |  Submit date:2022/04/02
Pseudolaric acid A  Hsp90 inhibitor  Apoptosis  NMR  Structure-activity relationship  Photoaffinity-based probe  Protein-ligand interaction  MOLECULAR CHAPERONE  PROTEIN  TARGET  CANCER  KINASE  NMR  IDENTIFICATION  SELECTIVITY  BINDING  DESIGN  
Gut microbiota protects from triptolide-induced hepatotoxicity: Key role of propionate and its downstream signalling events 期刊论文
PHARMACOLOGICAL RESEARCH, 2020
Authors:  Huang, Jian-Feng;  Zhao, Qi;  Dai, Man-Yun;  Xiao, Xue-Rong;  Zhang, Ting;  Zhu, Wei-Feng;  Li, Fei
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Moringa oleifera Lam Seed Oil Augments Pentobarbital-Induced Sleeping Behaviors in Mice via GABAergic Systems 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020
Authors:  Liu, Wei-Liang;  Wu, Bai-Fen;  Shang, Jian-Hua;  Zhao, Yun-Li;  Huang, Ai-Xiang
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NMR-based Structural Classification, Identification, and Quantification of Triterpenoids from Edible Mushroom Ganoderma resinaceum 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020
Authors:  Huang, Yanjie;  Li, Xian;  Peng, Xingrong;  Adegoke, Adelakun Tiwalade;  Chen, Jianchao;  Su, Haiguo;  Hu, Guilin;  Wei, Gang;  Qiu, Minghua
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Celastrol ameliorates acute liver injury through modulation of PPAR alpha 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020
Authors:  Zhao, Qi;  Tang, Ping;  Zhang, Ting;  Huang, Jian-Feng;  Xiao, Xue-Rong;  Zhu, Wei-Feng;  Gonzalez, Frank J.;  Li, Fei
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The host jasmonic acid pathway regulates the transcriptomic changes of dodder and host plant under the scenario of caterpillar feeding on dodder 期刊论文
BMC PLANT BIOLOGY, 2019, 卷号: 19, 期号: 1, 页码: 12
Authors:  Qin, Yan;  Zhang, Jingxiong;  Hettenhausen, Christian;  Liu, Hui;  Li, Shalan;  Shen, Guojing;  Cao, Guoyan;  Wu, Jianqiang
Adobe PDF(1782Kb)  |  Favorite  |  View/Download:71/11  |  Submit date:2020/03/18
Caterpillar  Cuscuta  Defense  Dodder  Insect herbivory  Jasmonic acid  Systemic signal  Tobacco  Transcriptome