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Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
Authors:  Zhu,Yan-Yan;  Jin,Qiong;  Chen,Shan-Shan;  Jin,Dan-Ni;  Wang,Zhao-Jie;  He,Ying-Jie;  Chen,Hui-Cheng;  Zhao,Yun-Li;  Zhao,Li-Xing;  Dai,Zhi;  Luo,Xiao-Dong
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Neothalfine  Bisbenzylisoquinoline alkaloid  Metastatic colorectal cancer  Metabolomic  Mitochondrial apoptosis  SMALL MOLECULES  IRINOTECAN  RESISTANCE  CELL  IMMUNOTHERAPY  OPPORTUNITIES  CHEMOTHERAPY  VINORELBINE  ALKALOIDS  PATHWAY  
Potent Antihyperuricemic Triterpenoids Based on Two Unprecedented Scaffolds from the Leaves of Alstonia scholaris 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 11, 页码: 4158-4162
Authors:  Hu,Bin-Yuan;  Zhao,Yun-Li;  Xiong,Deng-Sen;  He,Ying-Jie;  Zhou,Zhong-Shun;  Zhu,Pei-Feng;  Wang,Zhao-Jie;  Wang,Yong-Liang;  Zhao,Li-Xing;  Luo,Xiao-Dong
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Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
Authors:  Dai,Zhi;  Liu,Hui;  Wang,Bei;  Yang,Dong;  Zhu,Yan-Yan;  Yan,Huan;  Zhu,Pei-Feng;  Liu,Ya-Ping;  Chen,Hui-Cheng;  Zhao,Yun-li;  Zhao,Li-Xing;  Zhao,Xu-Dong;  Liu,Hai-Yang;  Luo,Xiao-Dong
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Steroidal saponins  Structure-activity relationship  Tribulosaponin A  Glioma stem cells  ROS  SMALL MOLECULES  CARDIAC-ARREST  STEM-CELL  IDENTIFICATION  THERAPY  BRAIN  OPPORTUNITIES  GLIOMA  TUMORS  NOX2  
Diverse isoquinolines with anti-inflammatory and analgesic bioactivities from Hypecoum erectum 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 270, 页码: 113811
Authors:  Yuan,Hai-Lian;  Zhao,Yun-Li;  Qin,Xu-Jie;  Liu,Ya-Ping;  Yang,Xing-Wei;  Luo,Xiao-Dong
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Hypecoum erectum  Isoquinoline alkaloids  Anti-inflammatory activity  Analgesic activity  Inflammatory mediators  
Comparison of chemical constituents in diverse zanthoxylum herbs, and evaluation of their relative antibacterial and nematicidal activity 期刊论文
FOOD BIOSCIENCE, 2021, 卷号: 42, 页码: 101206
Authors:  Wang,Zhao-Jie;  Zhou,Ying;  Shi,Xiao-Long;  Xia,Xiao;  He,Ying-Jie;  Zhu,Yan-Yan;  Xie,Tian-Zhen;  Liu,Tie;  Xu,Xiang-Juan;  Luo,Xiao-Dong
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Zanthoxylum herbs  Antibacterial  Nematicidal  Mass spectrometry  BUNGEANUM MAXIM.  LIGNANS  IDENTIFICATION  ARMATUM  LEAVES  AMIDES  ROOTS  OILS  
Alkaloids of Toddalia asiatica (Rutaceae) 期刊论文
BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2021, 卷号: 95, 页码: 104244
Authors:  Chen,Shan-Shan;  Xie,Tian-Zhen;  He,Ying-Jie;  Liu,Yang-Yang;  Li,Lei;  Zhao,Li-Xing;  Luo,Xiao-Dong
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Toddalia asiatica  Rutaceae  Benzophenanthridine alkaloids  Furoquinoline alkaloids  Chemotaxonomy  Network analysis  
The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial 期刊论文
PHARMACEUTICAL BIOLOGY, 2021, 卷号: 59, 期号: 1, 页码: 484-493
Authors:  Gou,Zhong-Ping;  Zhao,Yun-Li;  Zou,Lin-Ling;  Wang,Ying;  Shu,Shi-Qing;  Zhu,Xiao-Hong;  Zheng,Li;  Shen,Qi;  Luo,Zhu;  Miao,Jia;  Wang,Yong-Sheng;  Luo,Xiao-Dong;  Feng,Ping
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Clinical safety  healthy subject  dose-escalation study  MONOTERPENOID INDOLE ALKALOIDS  FLIGHT MASS-SPECTROMETRY  EXTRACT  IDENTIFICATION  CONSTITUENTS  
C-19 Benzylisoquinoline Alkaloid with Unprecedented Architecture from Hypecoum erectum 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 23, 页码: 16764-16769
Authors:  Yuan,Hai-Lian;  Zhao,Yun-Li;  Hu,Kun;  He,Ying-Jie;  Yang,Xing-Wei;  Luo,Xiao-Dong
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OPIUM POPPY  BIOSYNTHESIS  APORPHINE  TETRANDRINE  PAPAVERINE  DISCOVERY  
Bioactivity Ingredients of Chaenomeles speciosa against Microbes: Characterization by LC-MS and Activity Evaluation 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 16, 页码: 4686-4696
Authors:  Wang,Zhao-Jie;  Jin,Dan-Ni;  Zhou,Ying;  Sang,Xu-Yan;  Zhu,Yan-Yan;  He,Ying-Jie;  Xie,Tian-Zhen;  Dai,Zhi;  Zhao,Yun-Li;  Luo,Xiao-Dong
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antimicrobial  Chaenomeles speciosa  LC-MS  metabolomics  LUNG INFLAMMATION  ANTIOXIDANT  FRUITS  POLYSACCHARIDE  
Development of a LC-HRMS based approach to boost structural annotation of isomeric citrus flavanones 期刊论文
PHYTOCHEMICAL ANALYSIS, 2021, 卷号: 32, 期号: 5, 页码: 749-756
Authors:  He,Ying-Jie;  Zhou,Ying;  Qin,Yan;  Zhou,Zhong-Shun;  Zhu,Meng;  Zhu,Yan-Yan;  Wang,Zhao-Jie;  Xie,Tian-Zhen;  Zhao,Li-Xing;  Luo,Xiao-Dong
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citrus flavanones  collision energy  fragmentation pattern  high‐  resolution mass spectrometry  ion ratio  RESOLUTION MASS-SPECTROMETRY  HESPERETIN ENANTIOMERS  QUANTIFICATION  NARINGENIN