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Tabernaesine J, a Novel Vincamine-Type Indole Alkaloid with 6/5/6/6/6/5/5 Heptacyclic-Ring System Scaffold from Tabernaemontana pachysiphon 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2022, 卷号: 40, 期号: 4, 页码: 475-479
Authors:  Yi,Wen-Fang;  Adelakun,Tiwalade A.;  Bai,Xue;  Zhang,Yu;  Hao,Xiao-Jiang
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Natural products  Alkaloids  Structure elucidation  Tabernaemontana pachysiphon  Tabernaesine J  BISINDOLE ALKALOIDS  A-I  ALGORITHM  
Notoginsenoids, a new class of hexa-nortriterpenoids from biotransformation of Panax notoginseng saponins 期刊论文
JOURNAL OF MOLECULAR STRUCTURE, 2022, 卷号: 1252, 页码: 132096
Authors:  Shang,Jia-Huan;  Li,Yong-Xiang;  Zhu,Hong-Tao;  Wang,Dong;  Qiao,Yi-Jun;  Yang,Chong-Ren;  Zhang,Ying-Jun
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Panax notoginseng saponins  Hexa-nortriterpenoids  Biotransformation  Antifungal activity  X-ray analysis  MICROBIAL TRANSFORMATION  ABSOLUTE-CONFIGURATION  20(S)-PROTOPANAXATRIOL  DIFFERENTIATION  BIOSYNTHESIS  MO-2(OAC)(4)  METABOLITES  
Novel nucleocapsid protein-targeting phenanthridine inhibitors of SARS-CoV-2 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 227, 页码: 113966
Authors:  Wang,Yi-Ting;  Long,Xin-Yan;  Ding,Xiao;  Fan,Shi-Rui;  Cai,Jie-Yun;  Yang,Bi-Juan;  Zhang,Xin-Fang;  Luo,Rong-hua;  Yang,Lian;  Ruan,Ting;  Ren,Juan;  Jing,Chen-Xu;  Zheng,Yong-Tang;  Hao,Xiao-Jiang;  Chen,Duo-Zhi
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Phenanthridine  Nucleocapsid protein  SARS-CoV-2  N-terminal domain  N-TERMINAL DOMAIN  CORONAVIRUS  
Small molecule QF84139 ameliorates cardiac hypertrophy via activating the AMPK signaling pathway 期刊论文
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 3, 页码: 588-601
Authors:  Li,Xu-xia;  Zhang,Peng;  Yang,Yang;  Wang,Jing-jing;  Zheng,Yan-jun;  Tan,Ji-liang;  Liu,Shen-yan;  Yan,Yong-ming;  Zhang,You-yi;  Cheng,Yong-xian;  Yang,Huang-tian
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cardiac hypertrophy  pyrazine derivative  QF84139  phenylephrine  transverse aortic constriction  AMPK signaling pathway  PROTEIN-KINASE  MAMMALIAN TARGET  OVERLOAD  METFORMIN  MACROPHAGES  MECHANISMS  MEDICINE  ALPHA  CELLS  MODEL  
Polycyclic polyprenylated acylphloroglucinols with immunosuppressive activity from Hypericum perforatum and absolute configurations assignment of previously reported analogues 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 114, 页码: 105144
Authors:  Guo,Yi;  Cao,Yunfang;  Qi,Changxing;  Tong,Qingyi;  Chen,Chunmei;  Yang,Jing;  Zhu,Hucheng;  Zhang,Yonghui
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Hypericum perforatum  Polycyclic polyprenylated acylphloroglucinols  Configuration assignment  Immunosuppressive activity  Neuroprotective activity  ST-JOHNS-WORT  PHLOROGLUCINOL DERIVATIVES  HYPERFORIN  INHIBITION  DEPRESSION  SKELETON  L.  
Pesimquinolones I-S, eleven new quinolone alkaloids produced by Penicillium simplicissimum and their inhibitory activity on NO production 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 104635
Authors:  Dai,Chong;  Li,Xiaoxin;  Zhang,Kailin;  Li,Xiao-Nian;  Wang,Wenjing;  Zang,Yi;  Chen,Xia;  Li,Qin;  Wei,Mengsha;  Chen,Chunmei;  Zhu,Hucheng;  Zhang,Yonghui
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Penicillium simplicissimum  Quinolone alkaloids  inhibitory activity on NO production  
Unprecedented polycyclic polyprenylated acylphloroglucinols with anti-Alzheimer's activity from St. John's wort 期刊论文
CHEMICAL SCIENCE, 2021, 卷号: 12, 期号: 34, 页码: 11438-11446
Authors:  Guo,Yi;  Huang,Fang;  Sun,Weiguang;  Zhou,Yuan;  Chen,Chunmei;  Qi,Changxing;  Yang,Jing;  Li,Xiao-Nian;  Luo,Zengwei;  Zhu,Hucheng;  Wang,Xiaochuan;  Zhang,Yonghui
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AMYLOID-BETA  NEUROFIBRILLARY DEGENERATION  HYPERFORIN  NEUROTOXICITY  PATHOGENESIS  INHIBITION  BACE1  DRUG  TAU  
Protect China's karst cave habitats 期刊论文
SCIENCE, 2021, 卷号: 374, 期号: 6568, 页码: 698-698
Authors:  Duan,Yi-Fan;  Li,Meng;  Xu,Ke-Wang;  Zhang,Liang;  Zhang,Li-Bing
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GESNERIACEAE  GUIZHOU  
Genomic basis of high-altitude adaptation in Tibetan Prunus fruit trees 期刊论文
CURRENT BIOLOGY, 2021, 卷号: 31, 期号: 17, 页码: 3848+
Authors:  Wang,Xia;  Liu,Shengjun;  Zuo,Hao;  Zheng,Weikang;  Zhang,Shanshan;  Huang,Yue;  Pingcuo,Gesang;  Ying,Hong;  Zhao,Fan;  Li,Yuanrong;  Liu,Junwei;  Yi,Ting-Shuang;  Zan,Yanjun;  Larkin,Robert M.;  Deng,Xiuxin;  Zeng,Xiuli;  Xu,Qiang
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R-PACKAGE  PHYLOGENETIC ANALYSIS  ANALYSIS TOOLKIT  ANALYSIS REVEALS  WEB SERVER  SELECTION  ELEMENT  IDENTIFICATION  ALIGNMENT  ACCURATE  
Genetic diversity of eleven Moringa oleifera Lam. germplasm introduced to Yunnan, southwest China and their backgrounds during worldwide cultivation 期刊论文
GENETIC RESOURCES AND CROP EVOLUTION, 2021, 卷号: 68, 期号: 8, 页码: 3345-3356
Authors:  He,Si-Teng;  Yang,Jing;  Wei,Jing;  Wu,Jiang-Chong;  Zheng,Yi-Xing;  Zhang,Yan-Ping;  Peng,Xing-Min
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Moringa oleifera Lam  Genetic structure  Plant introduction  Provenances  SSR