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Non-volatile acylphloroglucinol components from Eucalyptus robusta inhibit Zika virus by impairing RdRp activity of NS5 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105303
Authors:  Yao,Zhai-Wen;  Liu,Hui;  Zhou,Rui;  Feng,Mi-Yan;  Wang,Fang;  Qin,Xu-Jie;  Chen,Xiu-Xiu;  Zheng,Chang-Bo;  Luo,Rong-Hua;  Yang,Liu-Meng;  Cen,Shan;  Xiong,Si-Dong;  Liu,Hai-Yang;  Zheng,Yong-Tang
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Eucalyptus robusta  Acylphloroglucinol dimer  Eucalyprobusone G  Anti-ZIKV agent  NS5 RdRp  INFECTION  BINDING  GROWTH  
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
Authors:  Dai,Zhi;  Liu,Hui;  Wang,Bei;  Yang,Dong;  Zhu,Yan-Yan;  Yan,Huan;  Zhu,Pei-Feng;  Liu,Ya-Ping;  Chen,Hui-Cheng;  Zhao,Yun-li;  Zhao,Li-Xing;  Zhao,Xu-Dong;  Liu,Hai-Yang;  Luo,Xiao-Dong
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Steroidal saponins  Structure-activity relationship  Tribulosaponin A  Glioma stem cells  ROS  SMALL MOLECULES  CARDIAC-ARREST  STEM-CELL  IDENTIFICATION  THERAPY  BRAIN  OPPORTUNITIES  GLIOMA  TUMORS  NOX2  
Diverse isoquinolines with anti-inflammatory and analgesic bioactivities from Hypecoum erectum 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 270, 页码: 113811
Authors:  Yuan,Hai-Lian;  Zhao,Yun-Li;  Qin,Xu-Jie;  Liu,Ya-Ping;  Yang,Xing-Wei;  Luo,Xiao-Dong
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Hypecoum erectum  Isoquinoline alkaloids  Anti-inflammatory activity  Analgesic activity  Inflammatory mediators  
Paris Saponin VII Induces Apoptosis and Cell Cycle Arrest in Erythroleukemia Cells by a Mitochondrial Membrane Signaling Pathway 期刊论文
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21, 期号: 4, 页码: 498-507
Authors:  Lin,Xin;  Gajendran,Babu;  Varier,Krishnapriya M.;  Liu,Wuling;  Song,Jingrui;  Rao,Qing;  Wang,Chunlin;  Qiu,Jianfei;  Ni,Wei;  Qin,XuJie;  Wen,Min;  Liu,Haiyang;  Li,Yanmei
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Leukemia  Paris Saponin VII  HEL  cell cycle  apoptosis  membrane signaling pathway  
A natural acylphloroglucinol triggered antiproliferative possessions in HEL cells by impeding STAT3 signaling and attenuating angiogenesis in transgenic zebrafish model 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 141, 页码: 111877
Authors:  Hu,Mi;  Varier,Krishnapriya M.;  Li,Zhicao;  Qin,Xujie;  Rao,Qing;  Song,Jingrui;  Hu,Anling;  Hang,Yubing;  Yuan,Chunmao;  Gajendran,Babu;  Shu,Liping;  Wen,Min;  Li,Yanmei;  Liu,Haiyang
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Acylphloroglucinol  HEL cells  Intrinsic apoptotic pathway  Anti-angiogenesis  STAT3  Flk-1  CALLISTEMON-CITRINUS  TUMOR ANGIOGENESIS  DNA  DERIVATIVES  ANTICANCER  APOPTOSIS  ACTIVATION  INHIBITORS  TARGETS  LEAVES  
Acylphloroglucinols with acetylcholinesterase inhibitory effects from the fruits of Eucalyptus robusta (vol 103, 104127, 2020) 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 104579
Authors:  Liu,Hui;  He,Xiao-Zhi;  Feng,Mi-Yan;  Zeng,Yuan;  Rauwolf,Tyler J.;  Shao,Li-Dong;  Ni,Wei;  Yan,Hui;  Porco,John A.,Jr.;  Hao,Xiao-Jiang;  Qin,Xu-Jie;  Liu,Hai-Yang
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New diterpenoids from the rhizomes of Hedychium forrestii 期刊论文
NATURAL PRODUCT RESEARCH, 2021, 卷号: 35, 期号: 15, 页码: 2463-2469
Authors:  Wang,Wen-Hui;  Gao,Jie-Jie;  Zuo,Xiao-Fei;  Qin,Xu-Jie;  Liu,Hai-Yang;  Zhao,Qing
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Hedychium forrestii  hexanorditerpenoid  hedychins C and D  cytotoxicity  LABDANE-TYPE DITERPENOIDS  CONSTITUENTS  CYTOTOXICITY  CORONARIUM  YUNNANENSE  
AmAT19, an acetyltransferase from Astragalus membranaceus, catalyses specific 6 alpha-OH acetylation for tetracyclic triterpenes and steroids 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 33, 页码: 7186-7189
Authors:  Wang,Linlin;  Chen,Kuan;  Wang,Zilong;  Yi,Yang;  Zhang,Meng;  Hasan,Aobulikasimu;  Kuang,Yi;  Shaker,Sharpkate;  Yu,Rong;  Wang,Haotian;  Liu,Haiyang;  Ye,Min;  Qiao,Xue
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ACYLATION  ACYLTRANSFERASE  CYCLOASTRAGENOL  BAHD  
Resorcylic Acid Lactones Produced by an Endophytic Penicillium ochrochloron Strain from Kadsura angustifolia 期刊论文
PLANTA MEDICA, 2021, 卷号: 87, 期号: 3, 页码: 225-235
Authors:  Song,Hong Chuan;  Qin,Dan;  Liu,Hai Yang;  Dong,Jin Yan;  You,Chuan;  Wang,Yu Meng
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Kadsura angustifolia  Schisandraceae  resorcylic acid lactones  Penicillium ochrochloron  cytotoxity  antibacterial activity  FUNGAL METABOLITES  HYPOTHEMYCIN  STEREOCHEMISTRY  ZEARALENONE  MACROLIDES  PATHWAY  CELLS  
Polymethylated acylphloroglucinols from Rhodomyrtus tomentosa exert acetylcholinesterase inhibitory effects 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 107, 页码: 104519
Authors:  Qin,Xu-Jie;  Liu,Hui;  Li,Pan-Pan;  Ni,Wei;  He,Li;  Khan,Afsar;  Hao,Xiao-Jiang;  Liu,Hai-Yang
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Rhodomyrtus tomentosa  Polymethylated acyphloroglucinols  AChE inhibitory effect  Molecular docking  PHLOROGLUCINOL MEROTERPENOIDS  LEAVES  DERIVATIVES  TWIGS  BETA