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ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
Authors:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
Adobe PDF(1198Kb)  |  Favorite  |  View/Download:212/1  |  Submit date:2017/07/24
Abt-263  Sorafenib  Combination Therapy  Cancer  
The TRPC channel blocker SKF 96365 Inhibits Glioblastoma Cell Growth by Enhancing Reverse Mode of the Na+/Ca2+ Exchanger and Increasing Intracellular Ca2+ 期刊论文
出版物, 3111, 期号: 0, 页码: 1-45
Authors:  M Song;  D Chen;  S P Yu
Adobe PDF(1390Kb)  |  Favorite  |  View/Download:195/1  |  Submit date:2017/07/24
Skf 96365  Trpc Channel  Glioblastoma  Calcium  na+/ca2+ Exchanger  Cell Cycle  Cell Death  
Resveratrol Decrease Fructose-Induced Oxidative Stress Mediated by NADPH Oxidase via an AMPK-Dependent Mechanism1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-44
Authors:  Pei-Wen Cheng, PhD;  Wen-Yu Ho, MD, PhD;  Yu-Ting Su, MS;  Pei-Jung Lu,PhD;  Bo-Zone Chen MS;  Wen-Han Cheng, MS;  Wen-Hsien Lu, MD, MS;  Gwo-Ching Sun, MD;  Tung-Chen Yeh, MD;  Michael Hsiao DVM, PhD;  Ching-Jiunn Tseng, MD, PhD
Adobe PDF(1555Kb)  |  Favorite  |  View/Download:156/1  |  Submit date:2017/07/24
Ampk  Hypertension  Nucleus Tractus Solitarii  Nitrogen Oxides  Resveratrol  
The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1 期刊论文
出版物, 2111, 页码: 1-44
Authors:  1M S Grace;  T Lieu;  B Darby;  F C Abogadie;  N Veldhuis N W Bunnett;  P McIntyre
Adobe PDF(1611Kb)  |  Favorite  |  View/Download:131/1  |  Submit date:2017/07/24
Transient Receptor Potential Ion Channel  Trpv4  Protease Activated Receptor  Par2  Pain  Tyrosine Kinase  Bafetinib  
Parallel evolution of two AIM24 protein subfamilies and their conserved functions in ER stress tolerance in land plants 期刊论文
PLANT COMMUNICATIONS, 2023, 卷号: 4, 期号: 3, 页码: 100513
Authors:  Guan,Yanlong;  Chang,Guanxiao;  Zhao,Jinjie;  Wang,Qia;  Qin,Jiali;  Tang,Mengmeng;  Wang,Shuanghua;  Ma,Lan;  Ma,Jianchao;  Sun,Guiling;  Zhou,Yun;  Huang,Jinling
View  |  Adobe PDF(4970Kb)  |  Favorite  |  View/Download:10/4  |  Submit date:2024/07/17
Physcomitrium  Marchantia  unfolded protein response  lncRNA  AGROBACTERIUM-MEDIATED TRANSFORMATION  RETICULUM-ASSOCIATED DEGRADATION  ENDOPLASMIC-RETICULUM  TRANSCRIPTION FACTOR  VEGETATIVE GROWTH  ARABIDOPSIS  MUTAGENESIS  EXPRESSION  RESPONSES  GENES  
Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress 期刊论文
PHYTOMEDICINE, 2023, 卷号: 112, 页码: 154720
Authors:  Niu,Zhenpeng;  Tang,Guihua;  Wang,Xuenan;  Yang,Xu;  Zhao,Yueqin;  Wang,Yinyuan;  Liu,Qin;  Zhang,Fan;  Zhao,Yuhan;  Ding,Xiao;  Hao,Xiaojiang
View  |  Adobe PDF(11543Kb)  |  Favorite  |  View/Download:12/2  |  Submit date:2024/07/17
Lysosomal biogenesis  Autophagy  TFEB  TFE3  ER stress  IVDD  STAT3  TFE3  
Discovery of Natural Potent HMG-CoA Reductase Degraders for Lowering Cholesterol 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023
Authors:  Su,Xiao-Zheng;  Zhang,Lin-Fei;  Hu,Kun;  An,Yang;  Zhang,Qiao-Peng;  Tang,Jian-Wei;  Yan,Bing-Chao;  Li,Xing-Ren;  Cai,Jie;  Li,Xiao-Nian;  Sun,Han-Dong;  Jiang,Shi-You;  Puno,Pema-Tenzin
View  |  Adobe PDF(7289Kb)  |  Favorite  |  View/Download:23/2  |  Submit date:2024/07/10
Enzymes  Meroterpenoids  Natural Products  Proteomics  Semisynthesis  STATIN  FUNGUS  RISK  ACID  
Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction 期刊论文
NATURE CHEMICAL BIOLOGY, 2023, 卷号: 19, 期号: 4, 页码: 468-+
Authors:  Guo,Yingjie;  Zhang,Huan;  Yan,Chen;  Shen,Birong;  Zhang,Yue;  Guo,Xiangyang;  Sun,Sha;  Yu,Fan;  Yan,Jiayun;  Liu,Ronghe;  Zhang,Qianping;  Zhang,Di;  Liu,Haiyang;  Liu,Yang;  Zhang,Yaoyao;  Li,Wenlei;  Qin,Jiangyu;  Lv,He;  Wang,Zhaoxia;  Yuan,Yun;  Yang,Jie-Feng;  Zhong,Ya-Ting;  Gao,Song;  Zhou,Bing;  Liu,Lei;  Kong,Deling;  Hao,Xiaojiang;  Hu,Junjie;  Chen,Quan
View  |  Adobe PDF(25423Kb)  |  Favorite  |  View/Download:20/3  |  Submit date:2024/07/25
ENDOPLASMIC-RETICULUM  PROVIDE INSIGHT  MITOFUSIN 2  MFN1  DYNAMICS  REQUIRES  DEFECTS  FISSION  CELLS  
蕊木和奶子藤中生物碱类化学成分及其生物活性评价 学位论文
: 中国科学院大学, 2022
Authors:  陈谌
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夹竹桃科  Apocynaceae  蕊木  Kopsia arborea  奶子藤  Bousigonia mekongensis  单萜吲哚生物碱  Monoterterpene indole alkaloids  生物活性  Biological activity  
新型天然铁死亡诱导剂的筛选及作用机制研究 学位论文
: 中国科学院大学, 2022
Authors:  赵越勤
Adobe PDF(5494Kb)  |  Favorite  |  View/Download:30/0  |  Submit date:2024/05/14
肿瘤,天然产物,铁死亡,溶酶体,p53  Cancer, Nature products, Ferroptosis, Lysosome, p53