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Discovery of Natural Potent HMG-CoA Reductase Degraders for Lowering Cholesterol 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023
Authors:  Su,Xiao-Zheng;  Zhang,Lin-Fei;  Hu,Kun;  An,Yang;  Zhang,Qiao-Peng;  Tang,Jian-Wei;  Yan,Bing-Chao;  Li,Xing-Ren;  Cai,Jie;  Li,Xiao-Nian;  Sun,Han-Dong;  Jiang,Shi-You;  Puno,Pema-Tenzin
View  |  Adobe PDF(7289Kb)  |  Favorite  |  View/Download：176/39  |  Submit date：2024/07/10
Enzymes  Meroterpenoids  Natural Products  Proteomics  Semisynthesis  STATIN  FUNGUS  RISK  ACID  
Phomopsischalins A-C, polycyclic-fused cytochalasins from the endophytic fungus Phomopsis sp. shj2 and their abilities to induce lysosomal function 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2023, 卷号: 10, 期号: 9, 页码: 2218-2225
Authors:  Chen,Rong;  Guo,Li-Jing;  Li,Xue-Dan;  Li,Xing-Ren;  Hu,Kun;  Tang,Jian-Wei;  Ye,Zhen-Nan;  Yan,Bing-Chao;  Puno,Pema-Tenzin
View  |  Adobe PDF(1676Kb)  |  Favorite  |  View/Download：127/22  |  Submit date：2024/07/22
Abietane derived diterpenoids as Cav3.1 antagonists from Salvia digitaloides 期刊论文
CHINESE CHEMICAL LETTERS, 2023, 卷号: 34, 期号: 4, 页码: 107737
Authors:  Zhao,Jianjun;  Du,Shuzong;  Hu,Kun;  Hu,Yali;  Xia,Fan;  Ye,Yansong;  Yang,Jian;  Nian,Yin;  Xu,Gang
View  |  Adobe PDF(1277Kb)  |  Favorite  |  View/Download：162/34  |  Submit date：2024/07/22
10-Methylated 6  7  6 carbon ring system  Icetexane  Diterpenoid  Salvia digitaloides  Ca v 3  1 low voltage -gated Ca 2+channel  (LVGCC)  ROOTS  TANSHINLACTONE  CONSTITUENTS  ELUCIDATION  INHIBITORS  CHANNELS  SKELETON  SYSTEM  
Cytotoxic C-20 non-oxygenated ent-kaurane diterpenoids from Isodon wardii 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106512
Authors:  Tan,Qian;  Hu,Kun;  Li,Xiao-Nian;  Yang,Xing-Zhi;  Sun,Han-Dong;  Puno,Pema-Tenzin
View  |  Adobe PDF(3171Kb)  |  Favorite  |  View/Download：194/39  |  Submit date：2024/07/22
Isodon wardii  ent-Kauranoids  Cytotoxicity  Apoptosis  Cell cycle  
Wildfire associated with a deciduous broadleaved forest from the Neogene Baoshan Basin at the southeastern margin of the Tibetan Plateau 期刊论文
JOURNAL OF PALAEOGEOGRAPHY-ENGLISH, 2023, 卷号: 12, 期号: 3, 页码: 448-462
Authors:  Huang,Yong-Jiang;  Momohara,Arata;  Li,Shu-Feng;  Ji,Xue-Ping;  Qiu,Jian;  Jia,Lin-Bo;  Hu,Jin-Jin;  Ji,Yun-Heng;  Zhou,Zhe-Kun
View  |  Adobe PDF(6113Kb)  |  Favorite  |  View/Download：109/30  |  Submit date：2024/07/22
Charcoal  Fossil carpology  Salix  Sambucus  Precipitation seasonality  LATE PLIOCENE  EARLY PLEISTOCENE  FIRE REGIMES  SW CHINA  MONSOONAL CLIMATE  CHARCOAL RECORDS  SOUTHWEST CHINA  FOSSIL WOOD  SP-NOV  VEGETATION  
Isoxerophilins A and B, two diterpene heterodimers from Isodon xerophilus: structural elucidation and semisynthesis of isoxerophilin analogues 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2023, 卷号: 11, 期号: 1, 页码: 37-46
Authors:  Dai,Jia-Meng;  Yan,Bing-Chao;  Kong,Ling-Mei;  Hu,Kun;  Li,Xing-Ren;  Li,Xiao-Nian;  Sun,Han-Dong;  Li,Yan;  Puno,Pema-Tenzin
View  |  Adobe PDF(1181Kb)  |  Favorite  |  View/Download：171/16  |  Submit date：2024/05/09
ENT-KAURANE DITERPENOIDS  ABIETANE DITERPENOIDS  A-D  DIMERS  OXIDATION  CYCLOADDUCTS  ACTIVATION  LIGANDS  IBX  
Four new lanostane triterpenoids featuring extended pi-conjugated systems from the stems of Kadsura coccinea. 期刊论文
Natural products and bioprospecting, 2023, 卷号: 13, 期号: 1, 页码: 12-12
Authors:  Zhang, Qi-Qi;  Hu, Kun;  Sun, Han-Dong;  Puno, Pema-Tenzin
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Discovery of novel coffee diterpenoids with inhibitions on Ca(v)3.1 low voltage-gated Ca2+ channel 期刊论文
FOOD CHEMISTRY, 2022, 卷号: 376, 页码: 131923
Authors:  Hu,Guilin;  Dong,Ding;  Du,Shuzong;  Peng,Xingrong;  Wu,Mingkun;  Shi,Qiangqiang;  Hu,Kun;  Hong,Defu;  Wang,Xiaoyuan;  Zhou,Lin;  Nian,Yin;  Qiu,Minghua
Adobe PDF(4722Kb)  |  Favorite  |  View/Download：325/97  |  Submit date：2022/04/02
Coffea arabica L  Roasted coffee  Coffee diterpenoid  Cafestol  Kahweol  T-type Ca2+ channels  Ca(v)3.1 low voltage-gated Ca2+ channel  Ca(v)3.1 inhibitors  CALCIUM-CHANNELS  CAFESTOL  KAHWEOL  PHYSIOLOGY  ESTERS  NOMENCLATURE  PHARMACOLOGY  APOPTOSIS  FURANS  
A 2-oxoglutarate-dependent dioxygenase converts dihydrofuran to furan in Salvia diterpenoids 期刊论文
PLANT PHYSIOLOGY, 2022, 卷号: 188, 期号: 3, 页码: 1496-1506
Authors:  Song,Jiao-Jiao;  Fang,Xin;  Li,Chen-Yi;  Jiang,Yan;  Li,Jian-Xu;  Wu,Sheng;  Guo,Juan;  Liu,Yan;  Fan,Hang;  Huang,Yan-Bo;  Wei,Yu-Kun;  Kong,Yu;  Zhao,Qing;  Xu,Jing-Jing;  Hu,Yong-Hong;  Chen,Xiao-Ya;  Yang,Lei
Favorite  |  View/Download：181/0  |  Submit date：2022/04/02
MOLECULAR-CLONING  BIOSYNTHESIS  TANSHINONES  EVOLUTION  CYTOTOXICITY  SUPERFAMILY  OXYGENASES  APOPTOSIS  SYNTHASE  
New fossil evidence from the late Pliocene of Yunnan, South China, sheds light on the distribution and diversification of Sambucus L. (Adoxaceae) in the northern low latitudes 期刊论文
PALAEOBIODIVERSITY AND PALAEOENVIRONMENTS, 2022
Authors:  Huang, Yong-Jiang;  Zhu, Hai;  Hu, Jin-Jin;  Jia, Lin-Bo;  Zhou, Zhe-Kun
View  |  Adobe PDF(4170Kb)  |  Favorite  |  View/Download：158/37  |  Submit date：2024/04/30
Adoxaceae  Sambucus  Endocarp  Late Pliocene  South China  MIDDLE MIOCENE  SHOREA DIPTEROCARPACEAE  EARLY PLEISTOCENE  WINGED FRUITS  CLIMATE  VEGETATION  EOCENE  RECONSTRUCTION  DIPSACALES  BASIN