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Genomic and structural basis for evolution of tropane alkaloid biosynthesis 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 17, 页码: e2302448120
Authors:  Wang,Yong-Jiang;  Tain,Tian;  Yu,Jia-Yi;  Li,Jie;  Xu,Bingyan;  Chen,Jianghua;  D'Auria,John C.;  Huang,Jian-Ping;  Huang,Sheng-Xiong
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tropane alkaloids  evolution  biosynthesis  genome  structural biology  METHYLTRANSFERASE  REVEAL  
New Monoterpenoid Indole Alkaloids from Tabernaemontana crassa Inhibit beta-Amyloid42 Production and Phospho-Tau (Thr217) 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2, 页码: 1487
Authors:  Li,Sheng;  Han,Ling-Ling;  Huang,Ke-Pu;  Ma,Ye-Han;  Guo,Ling-Li;  Guo,Yarong;  Ran,Xiaoqian;  Yao,Yong-Gang;  Hao,Xiao-Jiang;  Luo,Rongcan;  Zhang,Yu
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Tabernaemontana crassa  monoterpenoid indole alkaloids  A beta 42  phospho-tau (Thr217)  Alzheimer's disease  ALZHEIMERS-DISEASE  BISINDOLE ALKALOIDS  CDK5  GEMFIBROZIL  PREVENTION  ALGORITHM  AUTOPHAGY  MODELS  PLANTS  MOUSE  
Guvermectin Biosynthesis Revealing the Key Role of a Phosphoribohydrolase and Structural Insight into the Active Glutamate of a Noncanonical Adenine Phosphoribosyltransferase 期刊论文
ACS CHEMICAL BIOLOGY, 2023
Authors:  Liu,Chongxi;  Wang,Zhiyan;  Chen,Yin;  Yan,Yijun;  Li,Lei;  Wang,Yong-Jiang;  Bai,Lu;  Li,Shanshan;  Zhang,Yanyan;  Wang,Xiangjing;  Huang,Sheng-Xiong;  Xiang,Wensheng
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CRYSTAL-STRUCTURE  GENOMES  
A 2-oxoglutarate-dependent dioxygenase converts dihydrofuran to furan in Salvia diterpenoids 期刊论文
PLANT PHYSIOLOGY, 2022, 卷号: 188, 期号: 3, 页码: 1496-1506
Authors:  Song,Jiao-Jiao;  Fang,Xin;  Li,Chen-Yi;  Jiang,Yan;  Li,Jian-Xu;  Wu,Sheng;  Guo,Juan;  Liu,Yan;  Fan,Hang;  Huang,Yan-Bo;  Wei,Yu-Kun;  Kong,Yu;  Zhao,Qing;  Xu,Jing-Jing;  Hu,Yong-Hong;  Chen,Xiao-Ya;  Yang,Lei
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MOLECULAR-CLONING  BIOSYNTHESIS  TANSHINONES  EVOLUTION  CYTOTOXICITY  SUPERFAMILY  OXYGENASES  APOPTOSIS  SYNTHASE  
Catalytic innovation underlies independent recruitment of polyketide synthases in cocaine and hyoscyamine biosynthesis 期刊论文
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 4994
Authors:  Tian, Tian;  Wang, Yong-Jiang;  Huang, Jian-Ping;  Li, Jie;  Xu, Bingyan;  Chen, Yin;  Wang, Li;  Yang, Jing;  Yan, Yijun;  Huang, Sheng-Xiong
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TROPANE ALKALOID BIOSYNTHESIS  CHAIN-LENGTH CONTROL  
New fossil evidence from the late Pliocene of Yunnan, South China, sheds light on the distribution and diversification of Sambucus L. (Adoxaceae) in the northern low latitudes 期刊论文
PALAEOBIODIVERSITY AND PALAEOENVIRONMENTS, 2022
Authors:  Huang, Yong-Jiang;  Zhu, Hai;  Hu, Jin-Jin;  Jia, Lin-Bo;  Zhou, Zhe-Kun
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Adoxaceae  Sambucus  Endocarp  Late Pliocene  South China  MIDDLE MIOCENE  SHOREA DIPTEROCARPACEAE  EARLY PLEISTOCENE  WINGED FRUITS  CLIMATE  VEGETATION  EOCENE  RECONSTRUCTION  DIPSACALES  BASIN  
Bauhinia (Leguminosae) Fossils from the Paleogene of Southwestern China and Its Species Accumulation in Asia 期刊论文
DIVERSITY-BASEL, 2022, 卷号: 14, 期号: 3, 页码: 173
Authors:  Jia, Lin-Bo;  Hu, Jin-Jin;  Zhang, Shi-Tao;  Su, Tao;  Spicer, Robert A.;  Liu, Jia;  Yang, Jiu-Cheng;  Zou, Pu;  Huang, Yong-Jiang;  Zhou, Zhe-Kun
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Polycyclic polyprenylated acylphloroglucinol derivatives with neuroprotective effects from Hypericum monogynum 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2021, 卷号: 23, 期号: 1, 页码: 73-81
Authors:  Zeng,Yan-Rong;  Li,Ya-Na;  Lou,Hua-Yong;  Jian,Jun-You;  Gu,Wei;  Huang,Lie-Jun;  Du,Guan-Hua;  Yuan,Chun-Mao;  Hao,Xiao-Jiang
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Hypericum monogynum  polycyclic polyprenylated acylphloroglucinols (PPAPs)  neuroprotective effects  structure-activity relationship  ST JOHNS WORT  PHLOROGLUCINOL DERIVATIVES  PRENYLATED PHLOROGLUCINOL  HYPERFORIN  ANALOGS  
Macroscopic fossil charcoals as proxy of a local fire linked to conifer-rich forest from the late Pliocene of northwestern Yunnan, Southwest China 期刊论文
PALAEOWORLD, 2021, 卷号: 30, 期号: 3, 页码: 551-561
Authors:  Huang,Yong-Jiang;  Shen,Hui;  Jia,Lin-Bo;  Li,Shu-Feng;  Su,Tao;  Nam,Gi-Soo;  Zhu,Hai;  Zhou,Zhe-Kun
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Neogene  palaeofire  palaeovegetation  precipitation seasonality  Sanying Formation  Tibetan Plateau  ATMOSPHERIC OXYGEN LEVELS  MONSOONAL CLIMATE  SP-NOV  VEGETATION  HISTORY  RECORD  BASIN  WOOD  RECONSTRUCTION  ARIDIFICATION  
Tropane alkaloid biosynthesis: a centennial review 期刊论文
NATURAL PRODUCT REPORTS, 2021, 卷号: 38, 期号: 9, 页码: 1634-1658
Authors:  Huang,Jian-Ping;  Wang,Yong-Jiang;  Tian,Tian;  Wang,Li;  Yan,Yijun;  Huang,Sheng-Xiong
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PUTRESCINE N-METHYLTRANSFERASE  TRANSFORMED ROOT CULTURES  2 TROPINONE REDUCTASES  ROLLE DES ACETATS  DATURA-STRAMONIUM  HYOSCYAMUS-NIGER  TOBACCO ALKALOIDS  ORNITHINE-DECARBOXYLASE  2-OXOGLUTARATE-DEPENDENT DIOXYGENASE  DIFFERENT STEREOSPECIFICITIES