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Isoscoparins R and S, two new ent-clerodane diterpenoids from Isodon scoparius 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2019, 卷号: 21, 期号: 10, 页码: 977-984
Authors:  Li, Xing-Ren;  Fu, Qiang;  Zhou, Min;  Hu, Kun;  Du, Xue;  Li, Xiao-Nian;  Sun, Han-Dong;  Yue, Jian-Bo;  Zhang, Hong-Bin;  Puno, Pema-Tenzin
Favorite  |  View/Download:21/0  |  Submit date:2019/10/28
Lamiaceae  ent-clerodane diterpenoids  Isodon scoparius  X-ray diffraction  autophagic activity  
Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors 期刊论文
PHARMACEUTICS, 2019, 卷号: 11, 期号: 9, 页码: 16
Authors:  Sajesh, Babu, V;  On, Ngoc H.;  Omar, Refaat;  Alrushaid, Samaa;  Kopec, Brian M.;  Wang, Wei-Guang;  Sun, Han-Dong;  Lillico, Ryan;  Lakowski, Ted M.;  Siahaan, Teruna J.;  Davies, Neal M.;  Puno, Pema-Tenzin;  Vanan, Magimairajan Issai;  Miller, Donald W.
Favorite  |  View/Download:17/0  |  Submit date:2019/12/20
blood-brain barrier (BBB)  drug delivery  transient modulation  HAV6 cadherin peptide  adenanthin  magnetic resonance imaging (MRI)  medulloblastoma  
Synergistic use of NMR computation and quantitative interproton distance analysis in the structural determination of neokadcoccitane A, a rearranged triterpenoid featuring an aromatic ring D from Kadsura coccinea 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 10, 页码: 1619-1626
Authors:  Xu, Hou-Chao;  Hu, Kun;  Shi, Xiao-Huo;  Tang, Jian-Wei;  Li, Xiao-Nian;  Sun, Han-Dong;  Puno, Pema-Tenzin
Favorite  |  View/Download:23/0  |  Submit date:2019/07/29
Structurally diverse diterpenoids from Isodon ternifolius collected from three regions 期刊论文
TETRAHEDRON, 2019, 卷号: 75, 期号: 19, 页码: 2797-2806
Authors:  Gou, Lei-Lei;  Hu, Kun;  Yang, Qian;  Li, Xiao-Nian;  Sun, Han-Dong;  Xiang, Chun-Lei;  Puno, Pema-Tenzin
Favorite  |  View/Download:34/0  |  Submit date:2019/06/24
Isodon ternifolius  Diterpenoids  Cytotoxic activity  NMR computation  ECD calculation  
(+)- and (-)-Alternarilactone A: Enantiomers with a Diepoxy-Cage-like Scaffold from an Endophytic Alternaria sp. 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2019, 卷号: 82, 期号: 4, 页码: 735-740
Authors:  Tang, Jian-Wei;  Xu, Hou-Chao;  Wang, Wei-Guang;  Hu, Kun;  Zhou, Yuan-Fei;  Chen, Rong;  Li, Xiao-Nian;  Du, Xue;  Sun, Han-Dong;  Puno, Pema-Tenzin
Favorite  |  View/Download:96/0  |  Submit date:2019/06/24
Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
Authors:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
Favorite  |  View/Download:112/0  |  Submit date:2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Isopenicins A-C: Two Types of Antitumor Meroterpenoids from the Plant Endophytic Fungus Penicillium sp. sh18 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 3, 页码: 771-775
Authors:  Tang, Jian-Wei;  Kong, Ling-Mei;  Zu, Wen-Yu;  Hu, Kun;  Li, Xiao-Nian;  Yan, Bing-Chao;  Wang, Wei-Guang;  Sun, Han-Dong;  Li, Yan;  Puno, Pema-Tenzin
Favorite  |  View/Download:121/0  |  Submit date:2019/03/18
Maoeriocalysins A-D, four novel ent-kaurane diterpenoids from Isodon eriocalyx and their structure determination utilizing quantum chemical calculation in conjunction with quantitative interproton distance analysis 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 1, 页码: 45-53
Authors:  Yang, Qian;  Hu, Kun;  Yan, Bing-Chao;  Liu, Miao;  Li, Xiao-Nian;  Sun, Han-Dong;  Puno, Pema-Tenzin
Favorite  |  View/Download:92/0  |  Submit date:2019/03/18
Adenanthin, a Natural ent-Kaurane Diterpenoid Isolated from the Herb Isodon adenantha Inhibits Adipogenesis and the Development of Obesity by Regulation of ROS 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 1, 页码: 16
Authors:  Hu, Jing;  Li, Xingren;  Tian, Weifeng;  Lu, Yanting;  Xu, Yuhui;  Wang, Fang;  Qin, Wanying;  Ma, Xiuli;  Puno, Pema-Tenzin;  Xiong, Wenyong
Favorite  |  View/Download:96/0  |  Submit date:2019/03/18
adenanthin  adipogenesis  reactive oxygen species  obesity  3T3-L1  
Synthesis of Novel ent-Kaurane-Type Diterpenoid Derivatives Effective for Highly Aggressive Tumor Cells 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 12, 页码: 9
Authors:  Hu, Yu;  Li, Xiao-Nian;  Ma, Ze-Jin;  Puno, Pema-Tenzin;  Zhao, Yong;  Zhao, Yan;  Xiao, Ye-Zhi;  Zhang, Wei;  Liu, Jing-Ping
Favorite  |  View/Download:36/0  |  Submit date:2019/03/18
ent-kaurane-type diterpenoid derivatives  antitumor  synthesis