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Phylogenetic patterns suggest frequent multiple origins of secondary metabolites across the seed-plant 'tree of life' 期刊论文
NATIONAL SCIENCE REVIEW, 2021, 卷号: 8, 期号: 4, 页码: nwaa105
Authors:  Zhang,Yongzeng;  Deng,Tao;  Sun,Lu;  Landis,Jacob B.;  Moore,Michael J.;  Wang,Hengchang;  Wang,Yuehua;  Hao,Xiaojiang;  Chen,Jijun;  Li,Shenghong;  Xu,Maonian;  Puno,Pema-Tenzin;  Raven,Peter H.;  Sun,Hang
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secondary metabolites  phylogenetic tree  phylogenetic signal  co-diversification  evolution  bioprospecting  seed plants  DIVERSIFICATION  EVOLUTION  DIVERSITY  SIGNAL  ANGIOSPERMS  CHEMISTRY  DEFENSES  FOSSIL  KEYS  
Neuroprotective schinortriterpenoids from Schisandra neglecta collected in Medog County, Tibet, China 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 104785
Authors:  Wang,Bin;  Hu,Kun;  Li,Xiao-Nian;  Sun,Han-Dong;  Qin,Hong-Bo;  Puno,Pema-Tenzin
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Schisandra neglecta  16  17-secopreschisanartane-type  schinortriterpenoids  Schisdilactones K?U  Quantum chemical calculation  Neuroprotective activity  DIBENZOCYCLOOCTADIENE LIGNANS  NORTRITERPENOIDS  CHINENSIS  STEMS  7,8-SECOLIGNANS  TRITERPENOIDS  
3-Hydroxy-4-methyldecanoic Acid-Containing Cyclotetradepsipeptides from an Endolichenic Beauveria sp. 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2021, 卷号: 84, 期号: 4, 页码: 1244-1253
Authors:  Zhou,Yuan-Fei;  Hu,Kun;  Wang,Fang;  Tang,Jian-Wei;  Zhang,Liang;  Sun,Han-Dong;  Cai,Xiang-Hai;  Puno,Pema-Tenzin
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DOUBLE-BLIND  CYCLODEPSIPEPTIDES  CONFIGURATION  METABOLITES  SUROTOMYCIN  VANCOMYCIN  ADULTS  FUNGI  H-1  
Schipropins A-J, structurally diverse triterpenoids from Schisandra propinqua 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 182, 页码: 112589
Authors:  Ma,Ren-Fen;  Hu,Kun;  Ding,Wen-Ping;  Wang,Bin;  He,Tao-Bin;  Li,Xiao-Nian;  Sun,Han-Dong;  Puno,Pema-Tenzin
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Schisandra propinqua  Lanostane-type triterpenoids  Cycloartane-type triterpenoids  Cytotoxicity  Anti-inflammation  NORTRITERPENOIDS  LIGNANS  SKELETON  
Chaetolactam A, an Azaphilone Derivative from the Endophytic Fungus Chaetomium sp. g1 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 1, 页码: 475-483
Authors:  Zu,Wen-Yu;  Tang,Jian-Wei;  Hu,Kun;  Zhou,Yuan-Fei;  Gou,Lei-Lei;  Su,Xiao-Zheng;  Lei,Xinxiang;  Sun,Han-Dong;  Puno,Pema-Tenzin
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MASS-SPECTROMETRY  A-D  CASPASE-3  H-1  
(-)-Isoscopariusin A, a Naturally Occurring Immunosuppressive Meroditerpenoid: Structure Elucidation and Scalable Chemical Synthesis 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 23, 页码: 12859-12867
Authors:  Yan,Bing-Chao;  Zhou,Min;  Li,Jian;  Li,Xiao-Nian;  He,Shi-Jun;  Zuo,Jian-Ping;  Sun,Han-Dong;  Li,Ang;  Puno,Pema-Tenzin
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bioactivity  cyclobutane  natural products  scalable synthesis  structure elucidation  
Spiro ent-Clerodane Dimers: Discovery and Green Approaches for a Scalable Biomimetic Synthesis 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 15, 页码: 5647-5651
Authors:  Li,Xing-Ren;  Yan,Bing-Chao;  Hu,Kun;  He,Shijun;  Sun,Han-Dong;  Zuo,Jianping;  Puno,Pema-Tenzin
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DIELS-ALDER REACTIONS  SENSITIZED PHOTOOXYGENATION  NATURAL-PRODUCTS  ACID  DITERPENOIDS  
Scopariusicide C, a novel cyclobutene-containing meroditerpenoid from artificially cultivated Isodon scoparius 期刊论文
TETRAHEDRON LETTERS, 2021, 卷号: 73, 页码: 153133
Authors:  Chen,Su-Ping;  Hu,Kun;  Li,Xing-Ren;  Zhang,Liang;  Sun,Han-Dong;  Puno,Pema-Tenzin
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Isodon scoparius  Meroditerpenoid  Residual dipolar coupling  Immunosuppressive activity  Antimicrobial activity  ENT-KAURANE DITERPENOIDS  
Bioinspired Network Analysis Enabled Divergent Syntheses and Structure Revision of Pentacyclic Cytochalasans 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 29, 页码: 15963-15971
Authors:  Wu,Hai;  Ding,Yiming;  Hu,Kun;  Long,Xianwen;  Qu,Chunlei;  Puno,Pema-Tenzin;  Deng,Jun
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bioinspired network analysis  biomimetic synthesis  natural products  pentacyclic cytochalasans  structure elucidation  DIELS-ALDER REACTION  ISOINDOLONE NUCLEUS  RING-SYSTEM  MEROCYTOCHALASANS  REASSIGNMENT  DESATURATION  GENERATION  ALKALOIDS  CARBONATE  SKELETONS  
A review on the relationship of mast cells and macrophages in breast cancer - Can herbs or natural products facilitate their anti-tumor effects? 期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 164, 页码: 105321
Authors:  Gou,Leilei;  Yue,Grace Gar-Lee;  Puno,Pema Tenzin;  Lau,Clara Bik-San
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Breast cancer  Mast cell  Macrophage  Natural products  Herbs  Extracts  TUMOR-ASSOCIATED MACROPHAGES  NF-KAPPA-B  MEDIATED ALLERGIC REACTIONS  PRO-INFLAMMATORY CYTOKINES  ANTIINFLAMMATORY ACTIVITY  ATOPIC-DERMATITIS  UMBROSA ROOT  TNF-ALPHA  IN-VIVO  C-KIT