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Cytochalasans from the Endophytic Fungus Phomopsis sp. shj2 and Their Antimigratory Activities | |
Yan, Bing-Chao; Wang, Wei-Guang; Kong, Ling-Mei; Tang, Jian-Wei; Du, Xue; Li, Yan; Puno, Pema-Tenzin | |
2022 | |
发表期刊 | JOURNAL OF FUNGI |
卷号 | 8期号:5页码:543 |
摘要 | Cytochalasans from the endophytic fungi featured structure diversity. Our previous study has disclosed that cytochalasans from the endophytic fungus Phomopsis sp. shj2 exhibited an antimigratory effect. Further chemical investigation on Phomopsis sp. shj2 has led to the discovery of seven new cytochalasans (1-7), together with four known ones. Their structures were elucidated through extensive spectroscopic data interpretation and single-crystal X-ray diffraction analysis. Compounds 1-3 and 8-11 exhibited antimigratory effects against MDA-MB-231 in vitro with IC50 values in the range of 1.01-10.42 mu M. |
关键词 | endophytic fungus Phomopsis cytochalasan antimigratory activity DERIVATIVES |
DOI | 10.3390/jof8050543 |
收录类别 | SCI |
WOS记录号 | WOS:000801898400001 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/74733 |
专题 | 中国科学院昆明植物研究所 |
推荐引用方式 GB/T 7714 | Yan, Bing-Chao,Wang, Wei-Guang,Kong, Ling-Mei,et al. Cytochalasans from the Endophytic Fungus Phomopsis sp. shj2 and Their Antimigratory Activities[J]. JOURNAL OF FUNGI,2022,8(5):543. |
APA | Yan, Bing-Chao.,Wang, Wei-Guang.,Kong, Ling-Mei.,Tang, Jian-Wei.,Du, Xue.,...&Puno, Pema-Tenzin.(2022).Cytochalasans from the Endophytic Fungus Phomopsis sp. shj2 and Their Antimigratory Activities.JOURNAL OF FUNGI,8(5),543. |
MLA | Yan, Bing-Chao,et al."Cytochalasans from the Endophytic Fungus Phomopsis sp. shj2 and Their Antimigratory Activities".JOURNAL OF FUNGI 8.5(2022):543. |
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