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Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 210, 页码: 115491
Authors:  Gou,Leilei;  Yue,Grace Gar-Lee;  Lee,Julia Kin -Ming;  Puno,Pema Tenzin;  Lau,Clara Bik-San
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Breast cancer  Metastasis  Natural products  Eriocalyxin B  Cancer recurrence  Cancer stem cells  Gut microbiome  NF-KAPPA-B  STEM-CELLS  MOLECULAR-MECHANISMS  EXTRACELLULAR-MATRIX  TUMOR-GROWTH  APOPTOSIS  ANGIOGENESIS  PROGRESSION  CARCINOMA  LEUKEMIA  
Structurally diverse spirocyclic polycyclic polyprenylated acylphloroglucinols from Hypericum ascyron Linn. and their anti-tumor activity 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 212, 页码: 113727
Authors:  Hu,Ya-Li;  Yue,Grace Gar-Lee;  Li,Xing-Ren;  Xu,Gang;  Lau,Clara Bik-San
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Hypericaceae  Polycyclic polyprenylated acylphloroglucinols  Spirocyclic polyprenylated acylphloroglucinols  HCT116 cells  Zebrafish model  Hypericum ascyron Linn  NATURAL-PRODUCTS  A-H  DERIVATIVES  FLOWERS  VEGF  
Oligosaccharide analysis of the backbone structure of the characteristic polysaccharide of Dendrobium officinale 期刊论文
FOOD HYDROCOLLOIDS, 2023, 卷号: 134, 页码: 108038
Authors:  Wong, Tin-Long;  Li, Li-Feng;  Zhang, Ji-Xia;  Zhang, Quan-Wei;  Zhang, Xue-Ting;  Zhou, Li-Shuang;  Fung, Hau-Yee;  Feng, Lei;  Cheng, Hui -Yuan;  Huo, Chu-Ying;  Liu, Man;  Bao, Wan-Rong;  Wu, Wen-Jie;  Lai, Cheuk-Hei;  Bai, Su -Ping;  Nie, Shao-Ping;  Puno, Pema-Tenzin;  Lau, Clara Bik-San;  Leung, Ping -Chung;  Han, Quan-Bin;  Sun, Han-Dong
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Isolation, structural elucidation, and bioactivity of cholestane derivatives from Ypsilandra thibetica 期刊论文
NEW JOURNAL OF CHEMISTRY, 2022, 卷号: 47, 期号: 1, 页码: 324-332
Authors:  Xie, Jing;  Zhang, Shi-Juan;  Yue, Grace Gar-Lee;  Yu, Ling-Ling;  Liu, Hui;  Ma, Wen-Yi;  Yan, Huan;  Ni, Wei;  Lau, Clara Bik-San;  Liu, Hai-Yang
View  |  Adobe PDF(1693Kb)  |  Favorite  |  View/Download：174/33  |  Submit date：2024/04/30
SPIROSTANE GLYCOSIDES  STEROIDAL SAPONINS  GROWTH  
A review on the relationship of mast cells and macrophages in breast cancer - Can herbs or natural products facilitate their anti-tumor effects? 期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 164, 页码: 105321
Authors:  Gou,Leilei;  Yue,Grace Gar-Lee;  Puno,Pema Tenzin;  Lau,Clara Bik-San
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Breast cancer  Mast cell  Macrophage  Natural products  Herbs  Extracts  TUMOR-ASSOCIATED MACROPHAGES  NF-KAPPA-B  MEDIATED ALLERGIC REACTIONS  PRO-INFLAMMATORY CYTOKINES  ANTIINFLAMMATORY ACTIVITY  ATOPIC-DERMATITIS  UMBROSA ROOT  TNF-ALPHA  IN-VIVO  C-KIT  
Potential neurotrophic activity and cytotoxicity of selected C21 steroidal glycosides from Cynanchum otophyllum 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2020, 页码: 7
Authors:  Dong, Jinrun;  Yue, Grace Gar-Lee;  Lee, Julia Kin-Ming;  Lau, Clara Bik-San;  Qiu, Minghua
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Cynanchum otophyllum  Neurotrophic activity  Cytotoxicity  Colon cancer cells  
Dendrobium officinale Kimura et Migo Improved Dry Eye Symptoms via Promoting Tear Production in an Experimental Dry Eye Rat Model 期刊论文
PHARMACOGNOSY MAGAZINE, 2020
Authors:  Zeng, Qiang;  Siu, Wing-Sum;  Ko, Chun-Hay;  Wong, Chun-Wai;  Bik-San Lau, Clara;  Wu, Zheng-Zhi;  Hu, Jiang-Miao;  Leung, Ping-Chung
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Actein Inhibits Tumor Growth and Metastasis in HER2-Positive Breast Tumor Bearing Mice via Suppressing AKT/mTOR and Ras/Raf/MAPK Signaling Pathways 期刊论文
FRONTIERS IN ONCOLOGY, 2020
Authors:  Wu, Xiao-Xiao;  Yue, Grace Gar-Lee;  Dong, Jin-Run;  Lam, Christopher Wai-Kei;  Wong, Chun-Kwok;  Qiu, Ming-Hua;  Lau, Clara Bik-San
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Inhibitory effect of different Dendrobium species on LPS-induced inflammation in macrophages via suppression of MAPK pathways 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2018, 卷号: 16, 期号: 7, 页码: 481-489
Authors:  Zeng Qiang;  Ko, Chun-Hay;  Siu, Wing-Sum;  Li Kai-Kai;  Wong, Chun-Wai;  Han Xiao-Qiang;  Yang Liu;  Lau, Clara Bik-San;  Hu Jiang-Miao;  Leung, Ping-Chung
Favorite  |  View/Download：193/0  |  Submit date：2018/09/17
Dendrobium Species  Anti-inflammation  Macrophage  Mapk Pathways  
Functional roles of eriocalyxin B in zebrafish revealed by transcriptome analysis 期刊论文
MOLECULAR OMICS, 2018, 卷号: 14, 期号: 3, 页码: 156-169
Authors:  Zhou, Xunian;  Cao, Cyanne Ye;  Wan, Angel Tsz-Yau;  Yue, Grace Gar-Lee;  Kwok, Frankie Hin-Fai;  Fung, Kwok-Pui;  Sun, Handong;  Lau, Clara Bik-San;  Puno, Pema-Tenzin;  Tsui, Stephen Kwok-Wing
Favorite  |  View/Download：403/0  |  Submit date：2018/07/16