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Non-volatile acylphloroglucinol components from Eucalyptus robusta inhibit Zika virus by impairing RdRp activity of NS5 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105303
Authors:  Yao,Zhai-Wen;  Liu,Hui;  Zhou,Rui;  Feng,Mi-Yan;  Wang,Fang;  Qin,Xu-Jie;  Chen,Xiu-Xiu;  Zheng,Chang-Bo;  Luo,Rong-Hua;  Yang,Liu-Meng;  Cen,Shan;  Xiong,Si-Dong;  Liu,Hai-Yang;  Zheng,Yong-Tang
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Eucalyptus robusta  Acylphloroglucinol dimer  Eucalyprobusone G  Anti-ZIKV agent  NS5 RdRp  INFECTION  BINDING  GROWTH  
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 210, 页码: 113068
Authors:  Dai,Zhi;  Liu,Hui;  Wang,Bei;  Yang,Dong;  Zhu,Yan-Yan;  Yan,Huan;  Zhu,Pei-Feng;  Liu,Ya-Ping;  Chen,Hui-Cheng;  Zhao,Yun-li;  Zhao,Li-Xing;  Zhao,Xu-Dong;  Liu,Hai-Yang;  Luo,Xiao-Dong
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Steroidal saponins  Structure-activity relationship  Tribulosaponin A  Glioma stem cells  ROS  SMALL MOLECULES  CARDIAC-ARREST  STEM-CELL  IDENTIFICATION  THERAPY  BRAIN  OPPORTUNITIES  GLIOMA  TUMORS  NOX2  
Diverse isoquinolines with anti-inflammatory and analgesic bioactivities from Hypecoum erectum 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 270, 页码: 113811
Authors:  Yuan,Hai-Lian;  Zhao,Yun-Li;  Qin,Xu-Jie;  Liu,Ya-Ping;  Yang,Xing-Wei;  Luo,Xiao-Dong
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Hypecoum erectum  Isoquinoline alkaloids  Anti-inflammatory activity  Analgesic activity  Inflammatory mediators  
Paris Saponin VII Induces Apoptosis and Cell Cycle Arrest in Erythroleukemia Cells by a Mitochondrial Membrane Signaling Pathway 期刊论文
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21, 期号: 4, 页码: 498-507
Authors:  Lin,Xin;  Gajendran,Babu;  Varier,Krishnapriya M.;  Liu,Wuling;  Song,Jingrui;  Rao,Qing;  Wang,Chunlin;  Qiu,Jianfei;  Ni,Wei;  Qin,XuJie;  Wen,Min;  Liu,Haiyang;  Li,Yanmei
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Leukemia  Paris Saponin VII  HEL  cell cycle  apoptosis  membrane signaling pathway  
A natural acylphloroglucinol triggered antiproliferative possessions in HEL cells by impeding STAT3 signaling and attenuating angiogenesis in transgenic zebrafish model 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 141, 页码: 111877
Authors:  Hu,Mi;  Varier,Krishnapriya M.;  Li,Zhicao;  Qin,Xujie;  Rao,Qing;  Song,Jingrui;  Hu,Anling;  Hang,Yubing;  Yuan,Chunmao;  Gajendran,Babu;  Shu,Liping;  Wen,Min;  Li,Yanmei;  Liu,Haiyang
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Acylphloroglucinol  HEL cells  Intrinsic apoptotic pathway  Anti-angiogenesis  STAT3  Flk-1  CALLISTEMON-CITRINUS  TUMOR ANGIOGENESIS  DNA  DERIVATIVES  ANTICANCER  APOPTOSIS  ACTIVATION  INHIBITORS  TARGETS  LEAVES  
New diterpenoids from the rhizomes of Hedychium forrestii 期刊论文
NATURAL PRODUCT RESEARCH, 2021, 卷号: 35, 期号: 15, 页码: 2463-2469
Authors:  Wang,Wen-Hui;  Gao,Jie-Jie;  Zuo,Xiao-Fei;  Qin,Xu-Jie;  Liu,Hai-Yang;  Zhao,Qing
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Hedychium forrestii  hexanorditerpenoid  hedychins C and D  cytotoxicity  LABDANE-TYPE DITERPENOIDS  CONSTITUENTS  CYTOTOXICITY  CORONARIUM  YUNNANENSE  
AmAT19, an acetyltransferase from Astragalus membranaceus, catalyses specific 6 alpha-OH acetylation for tetracyclic triterpenes and steroids 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 卷号: 19, 期号: 33, 页码: 7186-7189
Authors:  Wang,Linlin;  Chen,Kuan;  Wang,Zilong;  Yi,Yang;  Zhang,Meng;  Hasan,Aobulikasimu;  Kuang,Yi;  Shaker,Sharpkate;  Yu,Rong;  Wang,Haotian;  Liu,Haiyang;  Ye,Min;  Qiao,Xue
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ACYLATION  ACYLTRANSFERASE  CYCLOASTRAGENOL  BAHD  
Resorcylic Acid Lactones Produced by an Endophytic Penicillium ochrochloron Strain from Kadsura angustifolia 期刊论文
PLANTA MEDICA, 2021, 卷号: 87, 期号: 3, 页码: 225-235
Authors:  Song,Hong Chuan;  Qin,Dan;  Liu,Hai Yang;  Dong,Jin Yan;  You,Chuan;  Wang,Yu Meng
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Kadsura angustifolia  Schisandraceae  resorcylic acid lactones  Penicillium ochrochloron  cytotoxity  antibacterial activity  FUNGAL METABOLITES  HYPOTHEMYCIN  STEREOCHEMISTRY  ZEARALENONE  MACROLIDES  PATHWAY  CELLS  
Phytochemicals from the Leaves of Cyclocarya paliurus and their 11 beta-HSD1 Enzyme Inhibitory Effects 期刊论文
CHEMISTRY & BIODIVERSITY, 2021, 卷号: 18, 期号: 1
Authors:  Yan,Huan;  Li,Xiang;  Ni,Wei;  Zhao,Qing;  Leng,Ying;  Liu,Hai-Yang
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Cyclocarya paliurus  dammarane-type triterpenoid saponins  11β  -HSD1 enzyme  inhibitory activity  ANTIOXIDANT ACTIVITIES  CHEMICAL-CONSTITUENTS  DEHYDROGENASE TYPE-1  TRITERPENOIDS  POLYSACCHARIDE  SAPONINS  
Robustadial A and B from Eucalyptus globulus Labill. and their anticancer activity as selective tyrosyl-DNA phosphodiesterase 2 inhibitors 期刊论文
PHYTOTHERAPY RESEARCH, 2021, 卷号: 35, 期号: 9, 页码: 5282-5289
Authors:  Zhang,Yu;  He,Xiao-Zhi;  Yang,Hao;  Liu,Hai-Yang;  An,Lin-Kun
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anticancer  Eucalyptus globulus Labill  inhibitors  synergistic effect  tyrosyl-DNA phosphodiesterase  SMALL-MOLECULE INHIBITORS  1 TDP1