KIB OpenIR
A review on the relationship of mast cells and macrophages in breast cancer - Can herbs or natural products facilitate their anti-tumor effects?
Gou,Leilei; Yue,Grace Gar-Lee; Puno,Pema Tenzin; Lau,Clara Bik-San
2021
Source PublicationPHARMACOLOGICAL RESEARCH
ISSN1043-6618
Volume164Pages:105321
AbstractBreast cancer is an inflammation-related cancer whose tumor microenvironment is largely infiltrated by inflammatory cells. These inflammatory cells including mast cells and macrophages have been elucidated to be vital participants in breast tumor proliferation, survival, invasion and migration. However, the functions of mast cells and macrophages in breast cancer are quite distinct based on recent data. Mast cells exhibit both anti-tumoral and pro-tumoral functions on breast cancer, while high number of tumor-associated macrophages (TAMs) are strongly correlated with poor prognosis and higher risk of distant metastasis in breast cancer patients. Besides, many natural products/extracts have been reported to regulate mast cells and macrophages. In this review, the roles of mast cells and macrophages play in breast cancer are discussed and a summary of those natural products/herbs regulating the functions of mast cells or macrophages is also presented.
KeywordBreast cancer Mast cell Macrophage Natural products Herbs Extracts TUMOR-ASSOCIATED MACROPHAGES NF-KAPPA-B MEDIATED ALLERGIC REACTIONS PRO-INFLAMMATORY CYTOKINES ANTIINFLAMMATORY ACTIVITY ATOPIC-DERMATITIS UMBROSA ROOT TNF-ALPHA IN-VIVO C-KIT
DOI10.1016/j.phrs.2020.105321
WOS IDWOS:000615153300009
Citation statistics
Cited Times:10[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/73366
Collection中国科学院昆明植物研究所
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Chinese Univ Hong Kong, Inst Chinese Med, Shatin, Hksar, Peoples R China
3.Chinese Univ Hong Kong, State Key Lab Res Bioact & Clin Applicat Med Plan, Shatin, Hksar, Peoples R China
4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Gou,Leilei,Yue,Grace Gar-Lee,Puno,Pema Tenzin,et al. A review on the relationship of mast cells and macrophages in breast cancer - Can herbs or natural products facilitate their anti-tumor effects?[J]. PHARMACOLOGICAL RESEARCH,2021,164:105321.
APA Gou,Leilei,Yue,Grace Gar-Lee,Puno,Pema Tenzin,&Lau,Clara Bik-San.(2021).A review on the relationship of mast cells and macrophages in breast cancer - Can herbs or natural products facilitate their anti-tumor effects?.PHARMACOLOGICAL RESEARCH,164,105321.
MLA Gou,Leilei,et al."A review on the relationship of mast cells and macrophages in breast cancer - Can herbs or natural products facilitate their anti-tumor effects?".PHARMACOLOGICAL RESEARCH 164(2021):105321.
Files in This Item: Download All
File Name/Size DocType Version Access License
171-J04-143-苟-PR.pdf(1847KB)期刊论文出版稿开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Gou,Leilei]'s Articles
[Yue,Grace Gar-Lee]'s Articles
[Puno,Pema Tenzin]'s Articles
Baidu academic
Similar articles in Baidu academic
[Gou,Leilei]'s Articles
[Yue,Grace Gar-Lee]'s Articles
[Puno,Pema Tenzin]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Gou,Leilei]'s Articles
[Yue,Grace Gar-Lee]'s Articles
[Puno,Pema Tenzin]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: 171-J04-143-苟-PR.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.