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Functional roles of eriocalyxin B in zebrafish revealed by transcriptome analysis 期刊论文
MOLECULAR OMICS, 2018, 卷号: 14, 期号: 3, 页码: 156-169
Authors:  Zhou, Xunian;  Cao, Cyanne Ye;  Wan, Angel Tsz-Yau;  Yue, Grace Gar-Lee;  Kwok, Frankie Hin-Fai;  Fung, Kwok-Pui;  Sun, Handong;  Lau, Clara Bik-San;  Puno, Pema-Tenzin;  Tsui, Stephen Kwok-Wing
Favorite  |  View/Download:227/0  |  Submit date:2018/07/16
Natural small molecule bigelovin suppresses orthotopic colorectal tumor growth and inhibits colorectal cancer metastasis via IL6/STAT3 pathway 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 150, 页码: 189-199
Authors:  Li, Mingyue;  Yue, Grace Gar-Lee;  Song, Li-Hua;  Huang, Mao-Bo;  Lee, Julia Kin-Ming;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Tan, Ning-Hua;  Lau, Clara Bik-San
View  |  Adobe PDF(2333Kb)  |  Favorite  |  View/Download:33/2  |  Submit date:2018/07/02
Bigelovin  Colorectal Cancer  Metastasis  Tumor Microenvironment  Ll6/stat3 Pathway  
Elaborating the Role of Natural Products on the Regulation of Autophagy and their Potentials in Breast Cancer Therapy 期刊论文
CURRENT CANCER DRUG TARGETS, 2018, 卷号: 18, 期号: 3, 页码: 239-255
Authors:  Zhou, Xunian;  Yue, Grace Gar-Lee;  Tsui, Stephen Kwok-Wing;  Pu, Jianxin;  Fung, Kwok-Pui;  Lau, Clara Bik-San
Favorite  |  View/Download:23/0  |  Submit date:2018/05/08
Autophagy  Natural Products  Breast Cancer  Cancer Therapy  Mtor Signaling  Apoptosis  
Bigelovin triggered apoptosis in colorectal cancer in vitro and in vivo via upregulating death receptor 5 and reactive oxidative species 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 期号: 0, 页码: 42176
Authors:  Li, Mingyue;  Song, Li-Hua;  Yue, Grace Gar-Lee;  Lee, Julia Kin-Ming;  Zhao, Li-Mei;  Li, Lin;  Zhou, Xunian;  Tsui, Stephen Kwok-Wing;  Ng, Simon Siu-Man;  Fung, Kwok-Pui;  Tan, Ning-Hua;  Lau, Clara Bik-San
View  |  Adobe PDF(3294Kb)  |  Favorite  |  View/Download:68/10  |  Submit date:2017/04/17
Eriocalyxin B, a Novel Autophagy Inducer, Exerts Anti-tumor Activity Through the Suppression of Akt/mTOR/p70S6K Signaling Pathway In breast Cancer 期刊论文
Biochemical Pharmacology, 2017, 卷号: 142, 页码: 58–70
Authors:  Xunian Zhou;  Grace Gar-Lee Yue;  Andrew Man-Lok Chan;   Stephen Kwok-Wing Tsui;  Kwok-Pui Fung;   Handong Sun;  Jianxin Pu;  Clara Bik-San Lau
View  |  Adobe PDF(5871Kb)  |  Favorite  |  View/Download:46/11  |  Submit date:2017/11/20
Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 50, 页码: 82820-82835
Authors:  Zhou, Xunian;  Yue, Grace Gar-Lee;  Liu, Minghua;  Zuo, Zhili;  Lee, Julia Kin-Ming;  Li, Mingyue;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Sun, Handong;  Pu, Jianxin;  Lau, Clara Bik-San
View  |  Adobe PDF(13632Kb)  |  Favorite  |  View/Download:125/7  |  Submit date:2017/02/28
Eriocalyxin b  Angiogenesis  Vascular Endothelial Growth Factor (Vegf)  Vascular Endothelial Growth Factor Receptor 2(Vegfr-2)  Breast Cancer  
The beneficial potential of polyphenol-enriched fraction from Erigerontis Herba on metabolic syndrome 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2016, 卷号: 187, 页码: 94-103
Authors:  Wang, Yan Ping;  Wat, Elaine;  Koon, Chi Man;  Wong, Chun Wai;  Cheung, David Wing Shing;  Leung, Ping Chung;  Zhao, Qin Shi;  Fung, Kwok Pui;  Lau, Clara Bik San
View  |  Adobe PDF(1340Kb)  |  Favorite  |  View/Download:78/11  |  Submit date:2016/08/22
Erigerontis Herba  Polyphenol  Obesity  Hepatic Steatosis  Hyperlipidemia  Vasodilation  
RA-XII inhibits tumour growth and metastasis in breast tumour-bearing mice via reducing cell adhesion and invasion and promoting matrix degradation 期刊论文
SCIENTIFIC REPORTS, 2015, 卷号: 5
Authors:  Leung,Hoi-Wing;  Zhao,Si-Meng;  Yue,Grace Gar-Lee;  Lee,Julia Kin-Ming;  Fung,Kwok-Pui;  Leung,Ping-Chung;  Tan,Ning-Hua;  Lau,Clara Bik-San
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Cyclopeptide RA-V inhibits cell adhesion and invasion in both estrogen receptor positive and negative breast cancer cells via PI3K/AKT and NF-kappa B signaling pathways 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2015, 卷号: 1853, 期号: 8, 页码: 1827-1840
Authors:  Leung, Hoi-Wing;  Wang, Zhe;  Yue, Grace Gar-Lee;  Zhao, Si-Meng;  Lee, Julia Kin-Ming;  Fung, Kwok-Pui;  Leung, Ping-Chung;  Lau, Clara Bik-San;  Tan, Ning-Hua;  Lau,CBS (reprint author),Chinese Univ Hong Kong,Inst Chinese Med,Shatin,Hong Kong,Peoples R China.;  claralau@cuhk.edu.hk;  nhtan@mail.kib.ac.cn
View  |  Adobe PDF(2434Kb)  |  Favorite  |  View/Download:177/24  |  Submit date:2015/07/20
Cyclopeptide  Cell Adhesion  Cell Invasion  Metastasis  Breast Cancer  
Herb-drug interaction between an anti-HIV Chinese herbal SH formula and atazanavir in vitro and in vivo 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2015, 卷号: 162, 页码: 369-376
Authors:  Cheng, Bao-Hui;  Zhou, Xuelin;  Wang, Yan;  Chan, Judy Yuet-Wa;  Lin, Huang-Quan;  Or, Penelope M. Y.;  Wan, David Chi-Cheong;  Leung, Ping-Chung;  Fung, Kwok-Pui;  Wang, Yi-Fen;  Lau, Clara Bik-San;  Lau,CBS (reprint author),Chinese Univ Hong Kong,Inst Chinese Med,Shatin,Hong Kong,Peoples R China.;  claralau@cuhk.edu.hk
View  |  Adobe PDF(685Kb)  |  Favorite  |  View/Download:154/31  |  Submit date:2015/06/29
Sh Formula  Atazanavir  Anti-hiv  Cyp3a2  Herb-drug Interaction