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Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 210, 页码: 115491
作者:  Gou,Leilei;  Yue,Grace Gar-Lee;  Lee,Julia Kin -Ming;  Puno,Pema Tenzin;  Lau,Clara Bik-San
浏览  |  Adobe PDF(16654Kb)  |  收藏  |  浏览/下载:17/3  |  提交时间:2024/07/22
Breast cancer  Metastasis  Natural products  Eriocalyxin B  Cancer recurrence  Cancer stem cells  Gut microbiome  NF-KAPPA-B  STEM-CELLS  MOLECULAR-MECHANISMS  EXTRACELLULAR-MATRIX  TUMOR-GROWTH  APOPTOSIS  ANGIOGENESIS  PROGRESSION  CARCINOMA  LEUKEMIA  
Structurally diverse spirocyclic polycyclic polyprenylated acylphloroglucinols from Hypericum ascyron Linn. and their anti-tumor activity 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 212, 页码: 113727
作者:  Hu,Ya-Li;  Yue,Grace Gar-Lee;  Li,Xing-Ren;  Xu,Gang;  Lau,Clara Bik-San
Adobe PDF(6872Kb)  |  收藏  |  浏览/下载:20/12  |  提交时间:2024/07/25
Hypericaceae  Polycyclic polyprenylated acylphloroglucinols  Spirocyclic polyprenylated acylphloroglucinols  HCT116 cells  Zebrafish model  Hypericum ascyron Linn  NATURAL-PRODUCTS  A-H  DERIVATIVES  FLOWERS  VEGF  
Isolation, structural elucidation, and bioactivity of cholestane derivatives from Ypsilandra thibetica 期刊论文
NEW JOURNAL OF CHEMISTRY, 2022, 卷号: 47, 期号: 1, 页码: 324-332
作者:  Xie, Jing;  Zhang, Shi-Juan;  Yue, Grace Gar-Lee;  Yu, Ling-Ling;  Liu, Hui;  Ma, Wen-Yi;  Yan, Huan;  Ni, Wei;  Lau, Clara Bik-San;  Liu, Hai-Yang
浏览  |  Adobe PDF(1693Kb)  |  收藏  |  浏览/下载:56/13  |  提交时间:2024/04/30
SPIROSTANE GLYCOSIDES  STEROIDAL SAPONINS  GROWTH  
A review on the relationship of mast cells and macrophages in breast cancer - Can herbs or natural products facilitate their anti-tumor effects? 期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 164, 页码: 105321
作者:  Gou,Leilei;  Yue,Grace Gar-Lee;  Puno,Pema Tenzin;  Lau,Clara Bik-San
浏览  |  Adobe PDF(1847Kb)  |  收藏  |  浏览/下载:101/24  |  提交时间:2022/04/02
Breast cancer  Mast cell  Macrophage  Natural products  Herbs  Extracts  TUMOR-ASSOCIATED MACROPHAGES  NF-KAPPA-B  MEDIATED ALLERGIC REACTIONS  PRO-INFLAMMATORY CYTOKINES  ANTIINFLAMMATORY ACTIVITY  ATOPIC-DERMATITIS  UMBROSA ROOT  TNF-ALPHA  IN-VIVO  C-KIT  
Potential neurotrophic activity and cytotoxicity of selected C21 steroidal glycosides from Cynanchum otophyllum 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2020, 页码: 7
作者:  Dong, Jinrun;  Yue, Grace Gar-Lee;  Lee, Julia Kin-Ming;  Lau, Clara Bik-San;  Qiu, Minghua
收藏  |  浏览/下载:204/0  |  提交时间:2020/03/18
Cynanchum otophyllum  Neurotrophic activity  Cytotoxicity  Colon cancer cells  
Actein Inhibits Tumor Growth and Metastasis in HER2-Positive Breast Tumor Bearing Mice via Suppressing AKT/mTOR and Ras/Raf/MAPK Signaling Pathways 期刊论文
FRONTIERS IN ONCOLOGY, 2020
作者:  Wu, Xiao-Xiao;  Yue, Grace Gar-Lee;  Dong, Jin-Run;  Lam, Christopher Wai-Kei;  Wong, Chun-Kwok;  Qiu, Ming-Hua;  Lau, Clara Bik-San
浏览  |  Adobe PDF(1739Kb)  |  收藏  |  浏览/下载:201/81  |  提交时间:2021/01/05
Functional roles of eriocalyxin B in zebrafish revealed by transcriptome analysis 期刊论文
MOLECULAR OMICS, 2018, 卷号: 14, 期号: 3, 页码: 156-169
作者:  Zhou, Xunian;  Cao, Cyanne Ye;  Wan, Angel Tsz-Yau;  Yue, Grace Gar-Lee;  Kwok, Frankie Hin-Fai;  Fung, Kwok-Pui;  Sun, Handong;  Lau, Clara Bik-San;  Puno, Pema-Tenzin;  Tsui, Stephen Kwok-Wing
收藏  |  浏览/下载:341/0  |  提交时间:2018/07/16
Natural small molecule bigelovin suppresses orthotopic colorectal tumor growth and inhibits colorectal cancer metastasis via IL6/STAT3 pathway 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 150, 页码: 189-199
作者:  Li, Mingyue;  Yue, Grace Gar-Lee;  Song, Li-Hua;  Huang, Mao-Bo;  Lee, Julia Kin-Ming;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Tan, Ning-Hua;  Lau, Clara Bik-San
浏览  |  Adobe PDF(2333Kb)  |  收藏  |  浏览/下载:224/46  |  提交时间:2018/07/02
Bigelovin  Colorectal Cancer  Metastasis  Tumor Microenvironment  Ll6/stat3 Pathway  
Actein Inhibits the Proliferation and Adhesion of Human Breast Cancer Cells and Suppresses Migration in vivo 期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9, 页码: 1466
作者:  Wu, Xiao-Xiao;  Yue, Grace Gar-Lee;  Dong, Jin-Run;  Lam, Christopher Wai-Kei;  Wong, Chun-Kwok;  Qiu, Ming-Hua;  Lau, Clara Bik-San
收藏  |  浏览/下载:97/0  |  提交时间:2019/03/29
Actein Inhibits the Proliferation and Adhesion of Human Breast Cancer Cells and Suppresses Migration in vivo 期刊论文
PHYTOTAXA, 2018, 卷号: 382, 期号: 2, 页码: 182-192
作者:  Wu, Xiao-Xiao;  Yue, Grace Gar-Lee;  Dong, Jin-Run;  Lam, Christopher Wai-Kei;  Wong, Chun-Kwok;  Qiu, Ming-Hua;  Lau, Clara Bik-San
收藏  |  浏览/下载:146/0  |  提交时间:2018/12/27