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ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
作者:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
Adobe PDF(1198Kb)  |  收藏  |  浏览/下载:201/1  |  提交时间:2017/07/24
Abt-263  Sorafenib  Combination Therapy  Cancer  
The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1 期刊论文
出版物, 2111, 页码: 1-44
作者:  1M S Grace;  T Lieu;  B Darby;  F C Abogadie;  N Veldhuis N W Bunnett;  P McIntyre
Adobe PDF(1611Kb)  |  收藏  |  浏览/下载:126/1  |  提交时间:2017/07/24
Transient Receptor Potential Ion Channel  Trpv4  Protease Activated Receptor  Par2  Pain  Tyrosine Kinase  Bafetinib  
New Phenolic Dimers from Plant Paeonia suffruticosa and Their Cytotoxicity and NO Production Inhibition 期刊论文
Molecules, 2023
作者:  Qianqian Meng;  Shunyao Tong;  Yuqing Zhao;  Xingrong Peng;  Zhenghui Li;  Tao Feng;  Jikai Liu
浏览  |  Adobe PDF(1414Kb)  |  收藏  |  浏览/下载:451/62  |  提交时间:2023/10/07
Ciclopirox olamine sensitizes leukemia cells to natural killer cell-mediated cytolysis by upregulating NKG2DLs via the Akt signaling pathway 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2023, 卷号: 659, 页码: 10-19
作者:  Zhu,Yiying;  Zhao,Zhangxun;  Xue,Minggao;  Wang,Dan;  Su,Guifeng;  Ju,Xiaoman;  Yang,Qihong;  Zhang,Shaohua;  Fan,Dongmei;  Zhu,Huifang;  Yu,Min;  Li,Yan;  Kong,Lingmei;  Zhou,Hongyu
浏览  |  Adobe PDF(3425Kb)  |  收藏  |  浏览/下载:11/1  |  提交时间:2024/07/22
Ciclopirox olamine  Natural killer cells  NKG2D ligands  Immunotherapy  LIGANDS  RECEPTOR  GROWTH  
Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 210, 页码: 115491
作者:  Gou,Leilei;  Yue,Grace Gar-Lee;  Lee,Julia Kin -Ming;  Puno,Pema Tenzin;  Lau,Clara Bik-San
浏览  |  Adobe PDF(16654Kb)  |  收藏  |  浏览/下载:8/1  |  提交时间:2024/07/22
Breast cancer  Metastasis  Natural products  Eriocalyxin B  Cancer recurrence  Cancer stem cells  Gut microbiome  NF-KAPPA-B  STEM-CELLS  MOLECULAR-MECHANISMS  EXTRACELLULAR-MATRIX  TUMOR-GROWTH  APOPTOSIS  ANGIOGENESIS  PROGRESSION  CARCINOMA  LEUKEMIA  
Heterodimers with a cucurbitane-type triterpenoid skeleton from the branches of Elaeocarpus dubius 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 207, 页码: 113581
作者:  Hu,Dong-Bao;  Wei,Shu-Ya;  Yang,Jun;  Zhang,Dong-Dong;  Duan,Xiao-Yan;  Yan,Hui;  Yang,Xing-Zhi;  Bai,Xue;  Luo,Ji-Feng;  Yang,Jing-Hua;  Wang,Yun-Song;  Wang,Yue-Hu
浏览  |  Adobe PDF(1617Kb)  |  收藏  |  浏览/下载:2/2  |  提交时间:2024/07/25
Elaeocarpus dubius  Elaeocarpaceae  Cucurbitacins  Antioxidant  Neuroprotective  CONSTITUENTS  ELUCIDATION  GLYCOSIDES  
RUNX1-Regulated Signaling Pathways in Ovarian Cancer 期刊论文
BIOMEDICINES, 2023, 卷号: 11, 期号: 9, 页码: 2357
作者:  Chen,Yuanzhi;  He,Yingying;  Liu,Shubai
浏览  |  Adobe PDF(1447Kb)  |  收藏  |  浏览/下载:32/11  |  提交时间:2024/05/09
Runt-related transcription factor 1 (RUNX1)  ovarian cancer  apoptosis  signaling pathways  clinical therapeutic target  GROWTH-FACTOR  TRANSCRIPTION FACTORS  STEM-CELLS  RUNX1  STAT3  FAMILY  ACTIVATION  APOPTOSIS  LEUKEMIA  SURVIVAL  
Cytostatic Activity of Sanguinarine and a Cyanide Derivative in Human Erythroleukemia Cells Is Mediated by Suppression of c-MET/MAPK Signaling 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 9, 页码: 8113
作者:  Xu,Xinglian;  Deng,Lulu;  Tang,Yaling;  Li,Jiang;  Zhong,Ting;  Hao,Xiaojiang;  Fan,Yanhua;  Mu,Shuzhen
浏览  |  Adobe PDF(5829Kb)  |  收藏  |  浏览/下载:28/8  |  提交时间:2024/05/09
leukemia  sanguinarine  c-MET  MAPK  PI3K/mTOR  STAT3  MET  
生物碱(-)-Amathaspiramide F和(-)-Cephalotaxine 的不对称合成 学位论文
: 中国科学院大学, 2022
作者:  李路路
Adobe PDF(7942Kb)  |  收藏  |  浏览/下载:21/0  |  提交时间:2024/05/14
Ir/Cu协同催化  Ir/Cu synergistic catalysis  (-)-amathaspiramide F  (-)-Amathaspiramide F  (-)-cephalotaxine  (-)-Cephalotaxine  不对称合成  Asymmetric synthesis  
三尖杉属植物生物碱成分研究和活性酯碱资源评价 学位论文
: 中国科学院大学, 2022
作者:  余光兴
Adobe PDF(2195Kb)  |  收藏  |  浏览/下载:25/0  |  提交时间:2024/05/14
三尖杉属,种子,三尖杉生物碱,分离鉴定,酯碱资源评价  Cephalotaxus,Seeds,Cephalotaxine alkaloids,Isolation and identification,Ester alkaloids resources evaluation