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Glabridin inhibits migration and invasion by transcriptional inhibition of matrix metalloproteinase-9 through modulation of NF-B and AP-1 activity in human liver cancer cells lines 期刊论文
出版物, 3111, 期号: 0, 页码: 1—28
Authors:  Ming-Ju Hsieh;  Chiao-Wen Lin;  Shun-Fa Yang;  Mu-Kuan Chen;  Hui-Ling Chiou
Adobe PDF(1320Kb)  |  Favorite  |  View/Download:13/1  |  Submit date:2017/07/24
Glabridin  Migration  Invasion  Matrix Metalloproteinase-9  Hepatoma  
Physalis peruviana-Derived 4 beta-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 6, 页码: 13
Authors:  Ye, Zhen-Nan;  Yuan, Feng;  Liu, Jie-Qing;  Peng, Xing-Rong;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Qiu, Ming-Hua;  Li, Yan
Favorite  |  View/Download:5/0  |  Submit date:2019/07/29
4 beta HWE  Wnt signaling pathway  beta-catenin  colorectal cancer  
Aurovertin B sensitizes colorectal cancer cells to NK cell recognition and lysis 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 503, 期号: 4, 页码: 3057-3063
Authors:  Zhu, Huifang;  Wang, Fei;  Ju, Xiaoman;  Kong, Lingmei;  An, Tao;  Zhao, Zhangxun;  Liu, Jikai;  Li, Yan
Favorite  |  View/Download:324/0  |  Submit date:2018/10/22
Aurovertin B  Cytotoxicity  Immunotherapy  NK cell  NKG2D ligands  
12th全国天然有机化学学术会议摘要集 会议录
Editors:  中国化学会
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Research Progress of Polycyclic Polyprenylated Acylphloroglucinols 期刊论文
CHEMICAL REVIEWS, 2018, 卷号: 118, 期号: 7, 页码: 3508-3558
Authors:  Yang, Xing-Wei;  Grossman, Robert B.;  Xu, Gang
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Natural small molecule bigelovin suppresses orthotopic colorectal tumor growth and inhibits colorectal cancer metastasis via IL6/STAT3 pathway 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 150, 页码: 189-199
Authors:  Li, Mingyue;  Yue, Grace Gar-Lee;  Song, Li-Hua;  Huang, Mao-Bo;  Lee, Julia Kin-Ming;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Tan, Ning-Hua;  Lau, Clara Bik-San
View  |  Adobe PDF(2333Kb)  |  Favorite  |  View/Download:41/3  |  Submit date:2018/07/02
Bigelovin  Colorectal Cancer  Metastasis  Tumor Microenvironment  Ll6/stat3 Pathway  
Efficient synthesis of new phenanthridine Wnt/b-catenin signaling pathway agonists 期刊论文
European Journal of Medicinal Chemistry, 2018, 卷号: 157, 页码: 1491-1499
Authors:  Duozhi Chen;  Heng Zhang;  Chenxu Jing;  Xiaoli He;  Bijuan Yang;  Jieyun Cai;  Yunfu Zhou;  Xiaoming Song;  Lin Li;  Xiaojiang Hao
View  |  Adobe PDF(1966Kb)  |  Favorite  |  View/Download:67/29  |  Submit date:2019/03/27
Two novel diterpenoid heterodimers, Bisebracteolasins A and B, from Euphorbia ebracteolata Hayata, and the cancer chemotherapeutic potential of Bisebracteolasin A 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 1
Authors:  Yuan, Wen-Juan;  Ding, Xiao;  Wang, Zhe;  Yang, Bi-Juan;  Li, Xiao-Nian;  Zhang, Yu;  Chen, Duo-Zhi;  Li, Shun-Lin;  Chen, Quan;  Di, Ying-Tong;  Aisa, Haji Akber;  Hao, Xiao-Jiang
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Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells 期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 11, 页码: UNSP 1934
Authors:  Song, Lihua;  Wang, Zhe;  Wang, Yurong;  Guo, Di;  Yang, Jianhong;  Chen, Lijuan;  Tan, Ninghua
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Ra-xii  Cyclopeptide  Autophagy  Apoptosis  Mtor  Hepg2 Liver Cancer Cells  
Virtual screening of B-Raf kinase inhibitors: A combination of pharmacophore modelling, molecular docking, 3D-QSAR model and binding free energy calculation studies 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2017, 卷号: 70, 页码: 186-190
Authors:  Zhang, Wen;  Qiu, Kai-Xiong;  Yu, Fang;  Xie, Xiao-Guang;  Zhang, Shu-Qun;  Chen, Ya-Juan;  Xie, Hui-Ding
View  |  Adobe PDF(371Kb)  |  Favorite  |  View/Download:46/1  |  Submit date:2017/12/11
B-raf Kinase Inhibitors  Virtual Screening  Pharmacophore  Molecular Docking  3d Qsar  Binding Free Energy Calculation