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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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Glabridin inhibits migration and invasion by transcriptional inhibition of matrix metalloproteinase-9 through modulation of NF-B and AP-1 activity in human liver cancer cells lines
期刊论文
出版物, 3111, 期号: 0, 页码: 1—28
Authors:
Ming-Ju Hsieh
;
Chiao-Wen Lin
;
Shun-Fa Yang
;
Mu-Kuan Chen
;
Hui-Ling Chiou
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Submit date:2017/07/24
Glabridin
Migration
Invasion
Matrix Metalloproteinase-9
Hepatoma
Musarin, a novel protein with tyrosine kinase inhibitory activity from Trametes versicolor, accepted inhibits colorectal cancer stem cell growth
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 144, 页码: 112339
Authors:
He,YingYing
;
Liu,Shubai
;
Newburg,David S.
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View/Download:7/0
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Submit date:2022/04/02
Trametes versicolor
Cancer stem cell
Tyrosine kinase inhibitor
EGFR
Colorectal cancer
FACTOR RECEPTOR
POLYSACCHAROPEPTIDE
RESISTANCE
TARGET
EGFR
TOOL
PSP
DNA
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
Authors:
Zhu,Yan-Yan
;
Jin,Qiong
;
Chen,Shan-Shan
;
Jin,Dan-Ni
;
Wang,Zhao-Jie
;
He,Ying-Jie
;
Chen,Hui-Cheng
;
Zhao,Yun-Li
;
Zhao,Li-Xing
;
Dai,Zhi
;
Luo,Xiao-Dong
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View/Download:38/0
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Submit date:2022/04/02
Neothalfine
Bisbenzylisoquinoline alkaloid
Metastatic colorectal cancer
Metabolomic
Mitochondrial apoptosis
SMALL MOLECULES
IRINOTECAN
RESISTANCE
CELL
IMMUNOTHERAPY
OPPORTUNITIES
CHEMOTHERAPY
VINORELBINE
ALKALOIDS
PATHWAY
Discovery and synthesis of rocaglaol derivatives inducing apoptosis in HCT116 cells via suppression of MAPK signaling pathway
期刊论文
FITOTERAPIA, 2021, 卷号: 151, 页码: 104876
Authors:
Yang,Hao-Jie
;
Li,Ya-Nan
;
Yan,Chen
;
Yang,Jue
;
Zeng,Yan-Rong
;
Yi,Ping
;
Li,Yan-Mei
;
Hao,Xiao-Jiang
;
Yuan,Chun-Mao
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Submit date:2022/04/02
Dysoxylum gotadhora
Rocaglaol derivatives
HCT116
Cytotoxic activity
MAPK pathway
FLAVAGLINES
Tagitinin C induces ferroptosis through PERK-Nrf2-HO-1 signaling pathway in colorectal cancer cells
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2021, 卷号: 17, 期号: 11, 页码: 2703-2717
Authors:
Wei,Ruiran
;
Zhao,Yueqin
;
Wang,Juan
;
Yang,Xu
;
Li,Shunlin
;
Wang,Yinyuan
;
Yang,Xingzhi
;
Fei,Jimin
;
Hao,Xiaojiang
;
Zhao,Yuhan
;
Gui,Liming
;
Ding,Xiao
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Submit date:2022/04/02
ferroptosis
tagitinin C
ROS
ER stress
Nrf2-HO-1 pathway
ENDOPLASMIC-RETICULUM STRESS
ER-STRESS
OXIDATIVE STRESS
TUMOR-SUPPRESSOR
NRF2
DEATH
IRON
DIFFERENTIATION
MECHANISMS
RESISTANCE
Robustadial A and B from Eucalyptus globulus Labill. and their anticancer activity as selective tyrosyl-DNA phosphodiesterase 2 inhibitors
期刊论文
PHYTOTHERAPY RESEARCH, 2021, 卷号: 35, 期号: 9, 页码: 5282-5289
Authors:
Zhang,Yu
;
He,Xiao-Zhi
;
Yang,Hao
;
Liu,Hai-Yang
;
An,Lin-Kun
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View/Download:19/0
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Submit date:2022/04/02
anticancer
Eucalyptus globulus Labill
inhibitors
synergistic effect
tyrosyl-DNA phosphodiesterase
SMALL-MOLECULE INHIBITORS
1 TDP1
USP47 maintains the stemness of colorectal cancer cells and is inhibited by parthenolide
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2021, 卷号: 562, 页码: 21-28
Authors:
Zhang,Shaohua
;
Ju,Xiaoman
;
Yang,Qihong
;
Zhu,Yiying
;
Fan,Dongmei
;
Su,Guifeng
;
Kong,Lingmei
;
Li,Yan
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Submit date:2022/04/02
USP47
Cancer stem cell
Colorectal cancer
Parthenolide
Deubiquitinase
SESQUITERPENE LACTONE PARTHENOLIDE
DEUBIQUITINASES
STABILIZATION
LEUKEMIA
Design and synthesis of novel artemisinin hybrids with potent activities against human colorectal cancer cells in vitro and in vivo (vol 182, 111665, 2019)
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020
Authors:
Wang, Liang-Liang
;
Kong, Lingmei
;
Liu, Hui
;
Zhang, Yunqin
;
Zhang, Li
;
Liu, Xingyong
;
Yuan, Feng
;
Li, Yan
;
Zuo, Zhili
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Submit date:2021/01/05
Pestaloamides A and B, two spiro-heterocyclic alkaloid epimers from the plant endophytic fungus Pestalotiopsis sp. HS30
期刊论文
SCIENCE CHINA-CHEMISTRY, 2020
Authors:
Su, Xiao-Zheng
;
Zhu, Yi-Ying
;
Tang, Jian-Wei
;
Hu, Kun
;
Li, Xiao-Nian
;
Sun, Han-Dong
;
Li, Yan
;
Puno, Pema-Tenzin
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Submit date:2021/01/05
Parthenolide inhibits ubiquitin-specific peptidase 7 (USP7), Wnt signaling, and colorectal cancer cell growth
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020
Authors:
Li, Xue
;
Kong, Lingmei
;
Yang, Qihong
;
Duan, Aizhu
;
Ju, Xiaoman
;
Cai, Bicheng
;
Chen, Lin
;
An, Tao
;
Li, Yan
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View/Download:43/12
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Submit date:2021/01/05