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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis
期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
Authors:
I Hassan-Mohamed
;
C Giorgio
;
M Incerti
;
S Russo
;
D Pala
;
E B Pasquale
;
P Vicini
;
E Barocelli
;
S Rivara
;
M Mor
;
A Lodola
;
M Tognolini
Adobe PDF(1403Kb)
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Submit date:2017/07/24
Eph Kinase
Ephrin
Small Molecules
Angiogenesis
Bile Acid
Lithocholic Acid
ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1
期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
Authors:
Jingru Li
;
Yicheng Chen
;
Jiali Wan
;
Xin Liu
;
Chunrong Yu
;
Wenhua Li
Adobe PDF(1198Kb)
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Submit date:2017/07/24
Abt-263
Sorafenib
Combination Therapy
Cancer
The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)1
期刊论文
出版物, 3111, 期号: 0, 页码: 1-42
Authors:
C Pergola
;
J Gerstmeier
;
B Monch
;
B Çaliskan
;
S Luderer
;
C Weinige
;
D Barz
;
J Maczewsky
;
S Pace
;
A Rossi
;
L Sautebin
;
E Banoglu
;
O Werz
Adobe PDF(1387Kb)
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Submit date:2017/07/24
Long-term use of standardised ginkgo biloba extract for theprevention of Alzheimer’s disease (GuidAge): a randomisedplacebo-controlled trial
期刊论文
出版物, 3111, 期号: 0, 页码: 1—9
Authors:
Bruno Vellas
;
Nicola Coley
;
Pierre-Jean Ousset
;
Gilles Berrut
;
Jean-François Dartigues
;
Bruno Dubois
;
Hélène Grandjean
;
Florence Pasquier
;
François Piette
;
Philippe Robert
;
Jacques Touchon
;
Philippe Garnier
;
Hélène Mathiex-Fortunet
;
Sandrine Andrieu
;
for the GuidAge Study Group
Adobe PDF(230Kb)
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Submit date:2017/07/21
YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK
期刊论文
出版物, 3111, 期号: 0, 页码: 1-46
Authors:
Ling-Chu Chang
;
Hui-Yi Lin
;
Meng-Tung Tsai
;
Ruey-Hwang Chou
;
Fang-Yu Lee
;
Che-Ming Teng
;
Min-Tsang Hsieh
;
Hsin-Yi Hung
;
Li-Jiau Huang
;
Yung-Luen Yu
;
Sheng-Chu Kuo
Adobe PDF(1357Kb)
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Submit date:2017/07/24
Yc-1
Triple-negative Breast Cancer
Erk
Ezh2
C-cbl
The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1
期刊论文
出版物, 2111, 页码: 1-44
Authors:
1M S Grace
;
T Lieu
;
B Darby
;
F C Abogadie
;
N Veldhuis N W Bunnett
;
P McIntyre
Adobe PDF(1611Kb)
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Submit date:2017/07/24
Transient Receptor Potential Ion Channel
Trpv4
Protease Activated Receptor
Par2
Pain
Tyrosine Kinase
Bafetinib
Hepatic Stellate Celland Liver Microbiome-Specific Delivery System for Dihydrotanshinone I to Ameliorate Liver Fibrosis
期刊论文
ACS NANO, 2023, 卷号: 17, 期号: 23, 页码: 23608-23625
Authors:
Niu,Xia
;
Meng,Yanan
;
Cui,Jinjin
;
Li,Rui
;
Ding,Xiao
;
Niu,Bingyu
;
Chang,Ge
;
Xu,Ning
;
Li,Guiling
;
Wang,Yucheng
;
Wang,Lulu
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View/Download:169/26
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Submit date:2024/07/10
liver fibrosis
dihydrotanshinone I
hepaticstellate cells
vitamin A
cyclodextrin
liver microbiome
STRATEGY
THERAPY
TARGET
NANOPARTICLES
PATHWAY
Atractylodinol prevents pulmonary fibrosis through inhibiting TGF-β receptor 1 recycling by stabilizing vimentin
期刊论文
MOLECULAR THERAPY, 2023, 卷号: 31, 期号: 10, 页码: 3015-3033
Authors:
Hao,Mengjiao
;
Guan,Zhuoji
;
Zhang,Zhikang
;
Ai,Haopeng
;
Peng,Xing
;
Zhou,Huihao
;
Xu,Jun
;
Gu,Qiong
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Adobe PDF(8787Kb)
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Submit date:2024/07/25
INTERMEDIATE-FILAMENT PROTEIN
MECHANISMS
PATHWAYS
ADHESION
IDENTIFICATION
SMAD
Discovery of nontriterpenoids from the rot roots of Panax notoginseng with cytotoxicity and their molecular docking study and experimental validation
期刊论文
RSC ADVANCES, 2023, 卷号: 13, 期号: 16, 页码: 11037-11043
Authors:
Shang,Jia-Huan
;
Qiao,Yi-Jun
;
Zhu,Hong-Tao
;
Wang,Dong
;
Yang,Chong-Ren
;
Zhang,Ying-Jun
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Submit date:2024/05/09
THERAPY
RUNX1-Regulated Signaling Pathways in Ovarian Cancer
期刊论文
BIOMEDICINES, 2023, 卷号: 11, 期号: 9, 页码: 2357
Authors:
Chen,Yuanzhi
;
He,Yingying
;
Liu,Shubai
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Submit date:2024/05/09
Runt-related transcription factor 1 (RUNX1)
ovarian cancer
apoptosis
signaling pathways
clinical therapeutic target
GROWTH-FACTOR
TRANSCRIPTION FACTORS
STEM-CELLS
RUNX1
STAT3
FAMILY
ACTIVATION
APOPTOSIS
LEUKEMIA
SURVIVAL