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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis 期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
Authors:  I Hassan-Mohamed;  C Giorgio;  M Incerti;  S Russo;  D Pala;  E B Pasquale;  P Vicini;  E Barocelli;  S Rivara;  M Mor;  A Lodola;  M Tognolini
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Eph Kinase  Ephrin  Small Molecules  Angiogenesis  Bile Acid  Lithocholic Acid  
ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
Authors:  Jingru Li;  Yicheng Chen;  Jiali Wan;  Xin Liu;  Chunrong Yu;  Wenhua Li
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Abt-263  Sorafenib  Combination Therapy  Cancer  
The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-42
Authors:  C Pergola;  J Gerstmeier;  B Monch;  B Çaliskan;  S Luderer;  C Weinige;  D Barz;  J Maczewsky;  S Pace;  A Rossi;  L Sautebin;  E Banoglu;  O Werz
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Long-term use of standardised ginkgo biloba extract for theprevention of Alzheimer’s disease (GuidAge): a randomisedplacebo-controlled trial 期刊论文
出版物, 3111, 期号: 0, 页码: 1—9
Authors:  Bruno Vellas;  Nicola Coley;  Pierre-Jean Ousset;  Gilles Berrut;  Jean-François Dartigues;  Bruno Dubois;  Hélène Grandjean;  Florence Pasquier;  François Piette;  Philippe Robert;  Jacques Touchon;  Philippe Garnier;  Hélène Mathiex-Fortunet;  Sandrine Andrieu;  for the GuidAge Study Group
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YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK 期刊论文
出版物, 3111, 期号: 0, 页码: 1-46
Authors:  Ling-Chu Chang;  Hui-Yi Lin;  Meng-Tung Tsai;  Ruey-Hwang Chou;  Fang-Yu Lee;  Che-Ming Teng;  Min-Tsang Hsieh;  Hsin-Yi Hung;  Li-Jiau Huang;  Yung-Luen Yu;  Sheng-Chu Kuo
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Yc-1  Triple-negative Breast Cancer  Erk  Ezh2  C-cbl  
The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1 期刊论文
出版物, 2111, 页码: 1-44
Authors:  1M S Grace;  T Lieu;  B Darby;  F C Abogadie;  N Veldhuis N W Bunnett;  P McIntyre
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Transient Receptor Potential Ion Channel  Trpv4  Protease Activated Receptor  Par2  Pain  Tyrosine Kinase  Bafetinib  
Discovery of nontriterpenoids from the rot roots of Panax notoginseng with cytotoxicity and their molecular docking study and experimental validation 期刊论文
RSC ADVANCES, 2023, 卷号: 13, 期号: 16, 页码: 11037-11043
Authors:  Shang,Jia-Huan;  Qiao,Yi-Jun;  Zhu,Hong-Tao;  Wang,Dong;  Yang,Chong-Ren;  Zhang,Ying-Jun
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THERAPY  
RUNX1-Regulated Signaling Pathways in Ovarian Cancer 期刊论文
BIOMEDICINES, 2023, 卷号: 11, 期号: 9, 页码: 2357
Authors:  Chen,Yuanzhi;  He,Yingying;  Liu,Shubai
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Runt-related transcription factor 1 (RUNX1)  ovarian cancer  apoptosis  signaling pathways  clinical therapeutic target  GROWTH-FACTOR  TRANSCRIPTION FACTORS  STEM-CELLS  RUNX1  STAT3  FAMILY  ACTIVATION  APOPTOSIS  LEUKEMIA  SURVIVAL  
RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells 期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 886
Authors:  Chen,Yuanzhi;  He,Zhicheng;  Yang,Shuting;  Chen,Cheng;  Xiong,Wenyong;  He,Yingying;  Liu,Shubai
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Runt-related transcription factor 1 (RUNX1)  High-grade serous ovarian carcinoma (HGSOC)  Apoptosis  EMT  Clinical therapeutic target  EPITHELIAL-MESENCHYMAL TRANSITIONS  HEPATOCELLULAR-CARCINOMA  TRANSCRIPTION FACTOR  TP53 MUTATIONS  UP-REGULATION  TUMOR-GROWTH  MIGRATION  PROLIFERATION  INVASION  FOXO1  
Induction of RIPK3/MLKL-mediated necroptosis by Erigeron breviscapus injection exhibits potent antitumor effect 期刊论文
FRONTIERS IN PHARMACOLOGY, 2023, 卷号: 14, 页码: 1219362
Authors:  Guo,Xiuping;  Li,Rui;  Cui,Jinjin;  Hu,Chujuan;  Yu,Haoyang;  Ren,Ling;  Cheng,Yangyang;  Jiang,Jiandong;  Ding,Xiao;  Wang,Lulu
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Erigeron breviscapus injection  Dengzhanxixin  Erigeron breviscapus (Vant  ) Hand  -Mazz  colorectal cancer  necroptosis  drug resistance  TUMOR-NECROSIS-FACTOR  COLORECTAL-CANCER  NATURAL COMPOUNDS  SCUTELLARIN  APOPTOSIS  PROLIFERATION  MACROPHAGES  MIGRATION  INVASION  THERAPY