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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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UniPR129 is a competitive small molecule Eph-ephrin antagonist blocking in vitro angiogenesis at low micromolar concentrations Eph antagonist and angiogenesis
期刊论文
出版物, 3111, 期号: 0, 页码: 1-32
Authors:
I Hassan-Mohamed
;
C Giorgio
;
M Incerti
;
S Russo
;
D Pala
;
E B Pasquale
;
P Vicini
;
E Barocelli
;
S Rivara
;
M Mor
;
A Lodola
;
M Tognolini
Adobe PDF(1403Kb)
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Submit date:2017/07/24
Eph Kinase
Ephrin
Small Molecules
Angiogenesis
Bile Acid
Lithocholic Acid
ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21 (CIP1/WAF1) in human cancer cells1
期刊论文
出版物, 3111, 期号: 0, 页码: 1-35
Authors:
Jingru Li
;
Yicheng Chen
;
Jiali Wan
;
Xin Liu
;
Chunrong Yu
;
Wenhua Li
Adobe PDF(1198Kb)
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Submit date:2017/07/24
Abt-263
Sorafenib
Combination Therapy
Cancer
The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)1
期刊论文
出版物, 3111, 期号: 0, 页码: 1-42
Authors:
C Pergola
;
J Gerstmeier
;
B Monch
;
B Çaliskan
;
S Luderer
;
C Weinige
;
D Barz
;
J Maczewsky
;
S Pace
;
A Rossi
;
L Sautebin
;
E Banoglu
;
O Werz
Adobe PDF(1387Kb)
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Submit date:2017/07/24
Long-term use of standardised ginkgo biloba extract for theprevention of Alzheimer’s disease (GuidAge): a randomisedplacebo-controlled trial
期刊论文
出版物, 3111, 期号: 0, 页码: 1—9
Authors:
Bruno Vellas
;
Nicola Coley
;
Pierre-Jean Ousset
;
Gilles Berrut
;
Jean-François Dartigues
;
Bruno Dubois
;
Hélène Grandjean
;
Florence Pasquier
;
François Piette
;
Philippe Robert
;
Jacques Touchon
;
Philippe Garnier
;
Hélène Mathiex-Fortunet
;
Sandrine Andrieu
;
for the GuidAge Study Group
Adobe PDF(230Kb)
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Submit date:2017/07/21
YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK
期刊论文
出版物, 3111, 期号: 0, 页码: 1-46
Authors:
Ling-Chu Chang
;
Hui-Yi Lin
;
Meng-Tung Tsai
;
Ruey-Hwang Chou
;
Fang-Yu Lee
;
Che-Ming Teng
;
Min-Tsang Hsieh
;
Hsin-Yi Hung
;
Li-Jiau Huang
;
Yung-Luen Yu
;
Sheng-Chu Kuo
Adobe PDF(1357Kb)
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Submit date:2017/07/24
Yc-1
Triple-negative Breast Cancer
Erk
Ezh2
C-cbl
The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1
期刊论文
出版物, 2111, 页码: 1-44
Authors:
1M S Grace
;
T Lieu
;
B Darby
;
F C Abogadie
;
N Veldhuis N W Bunnett
;
P McIntyre
Adobe PDF(1611Kb)
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Submit date:2017/07/24
Transient Receptor Potential Ion Channel
Trpv4
Protease Activated Receptor
Par2
Pain
Tyrosine Kinase
Bafetinib
High-Throughput In Vitro Gene Expression Profile to Screen of Natural Herbals for Breast Cancer Treatment
期刊论文
FRONTIERS IN ONCOLOGY, 2021, 卷号: 11
Authors:
Kui,Ling
;
Kong,Qinghua
;
Yang,Xiaonan
;
Pan,Yunbing
;
Xu,Zetan
;
Wang,Shouling
;
Chen,Jian
;
Wei,Kunhua
;
Zhou,Xiaolei
;
Yang,Xingzhi
;
Wu,Tingqin
;
Mastan,Anthati
;
Liu,Yao
;
Miao,Jianhua
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View/Download:19/0
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Submit date:2022/04/02
breast cancer
traditional Chinese medicine (TCM)
high-throughput sequencing
transcriptome analysis
WGCNA
COEXPRESSION NETWORK ANALYSIS
IL-17 RECEPTOR
RNA-SEQ
IDENTIFICATION
KINASE
CELLS
TRANSCRIPTOME
INDUCTION
PRODUCTS
PROMOTES
Prostaglandin E1 Is an Efficient Molecular Tool for Forest Leech Blood Sucking
期刊论文
FRONTIERS IN VETERINARY SCIENCE, 2021, 卷号: 7, 页码: 615915
Authors:
Zheng,Fenshuang
;
Zhang,Min
;
Yang,Xingwei
;
Wu,Feilong
;
Wang,Gan
;
Feng,Xingxing
;
Ombati,Rose
;
Zuo,Ruiling
;
Yang,Canju
;
Liu,Jun
;
Lai,Ren
;
Luo,Xiaodong
;
Long,Chengbo
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Submit date:2022/04/02
leech
blood-sucking
prostaglandin E1
anticoagulant
Haemadipsa sylvestris
MEDICINAL LEECH
PGE1
INFLAMMATION
THERAPY
PAIN
E-1
Tagitinin C induces ferroptosis through PERK-Nrf2-HO-1 signaling pathway in colorectal cancer cells
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2021, 卷号: 17, 期号: 11, 页码: 2703-2717
Authors:
Wei,Ruiran
;
Zhao,Yueqin
;
Wang,Juan
;
Yang,Xu
;
Li,Shunlin
;
Wang,Yinyuan
;
Yang,Xingzhi
;
Fei,Jimin
;
Hao,Xiaojiang
;
Zhao,Yuhan
;
Gui,Liming
;
Ding,Xiao
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Submit date:2022/04/02
ferroptosis
tagitinin C
ROS
ER stress
Nrf2-HO-1 pathway
ENDOPLASMIC-RETICULUM STRESS
ER-STRESS
OXIDATIVE STRESS
TUMOR-SUPPRESSOR
NRF2
DEATH
IRON
DIFFERENTIATION
MECHANISMS
RESISTANCE
Neothalfine, a potent natural anti-tumor agent against metastatic colorectal cancer and its primary mechanism
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 115849
Authors:
Zhu,Yan-Yan
;
Jin,Qiong
;
Chen,Shan-Shan
;
Jin,Dan-Ni
;
Wang,Zhao-Jie
;
He,Ying-Jie
;
Chen,Hui-Cheng
;
Zhao,Yun-Li
;
Zhao,Li-Xing
;
Dai,Zhi
;
Luo,Xiao-Dong
View
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Submit date:2022/04/02
Neothalfine
Bisbenzylisoquinoline alkaloid
Metastatic colorectal cancer
Metabolomic
Mitochondrial apoptosis
SMALL MOLECULES
IRINOTECAN
RESISTANCE
CELL
IMMUNOTHERAPY
OPPORTUNITIES
CHEMOTHERAPY
VINORELBINE
ALKALOIDS
PATHWAY