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Discovery and bioinspired total syntheses of unprecedented sesquiterpenoid dimers unveiled bifurcating [4+2] cycloaddition and target differentiation of enantiomers 期刊论文
CHEMICAL SCIENCE, 2024, 卷号: 15, 期号: 4
Authors:  He, Tao-Bin;  Yan, Bing-Chao;  Zhou, Yuan-Fei;  Sang, Yue-Qian;  Li, Xiao-Nian;  Sun, Han-Dong;  Wang, Chu;  Xue, Xiao-Song;  Puno, Pema-Tenzin
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DIELS-ALDER REACTION  BIOMIMETIC SYNTHESES  EFFICIENT ACCESS  DEHYDROGENATION  CYCLOHEXANONES  BIOSYNTHESIS  CONVERSION  OXIDATION  DYNAMICS  PHENOLS  
Cyclobutane-Containing Meroditerpenoids, (+)-Isoscopariusins B and C: Structure Elucidation and Biomimetic Synthesis 期刊论文
ORGANIC LETTERS, 2023, 卷号: 25, 期号: 17, 页码: 2981-2985
Authors:  Li,Ming-Xiang;  Yan,Bing-Chao;  Zhou,Min;  Li,Xing-Ren;  Li,Xiao-nian;  He,Shi-Jun;  Sun,Han-Dong;  Puno,Pema-Tenzin
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2+2 PHOTOCYCLOADDITION REACTIONS  VISIBLE-LIGHT PHOTOCATALYSIS  LEWIS-ACID CATALYSIS  CYCLOADDITIONS  DERIVATIVES  
Discovery and Biomimetic Semisynthesis of Spirophyllines A-D from Uncaria rhynchophylla 期刊论文
ORGANIC LETTERS, 2023, 卷号: 25, 期号: 24, 页码: 4434-4438
Authors:  Zhou,Hao-Feng;  Li,Wen-Yan;  Wu,Qi;  Ren,Jian;  Peng,Li-Yan;  Li,Xiao-Nian;  Zhao,Qin-Shi
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ATRIAL  INHIBITORS  CHANNELS  
Discovery of Natural Potent HMG-CoA Reductase Degraders for Lowering Cholesterol 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023
Authors:  Su,Xiao-Zheng;  Zhang,Lin-Fei;  Hu,Kun;  An,Yang;  Zhang,Qiao-Peng;  Tang,Jian-Wei;  Yan,Bing-Chao;  Li,Xing-Ren;  Cai,Jie;  Li,Xiao-Nian;  Sun,Han-Dong;  Jiang,Shi-You;  Puno,Pema-Tenzin
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Enzymes  Meroterpenoids  Natural Products  Proteomics  Semisynthesis  STATIN  FUNGUS  RISK  ACID  
Pegriseofamines A-E: Five cyclopiazonic acid related indole alkaloids from the fungus Penicillium griseofulvum 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 136, 页码: 106553
Authors:  Liang,Yu;  Liao,Hong;  Chen,Xuanni;  Wang,Qiwei;  Li,Qin;  Shen,Yong;  Zheng,Yuyi;  Li,Xiao-Nian;  Zhu,Hucheng;  Li,Dongyan;  Sun,Weiguang;  Chen,Chunmei;  Zhang,Yonghui
View  |  Adobe PDF(11018Kb)  |  Favorite  |  View/Download：19/6  |  Submit date：2024/07/22
Penicillium griseofulvum  Alkaloid  Cyclopiazonic acid  Immunosuppression activity  
Cytotoxic C-20 non-oxygenated ent-kaurane diterpenoids from Isodon wardii 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106512
Authors:  Tan,Qian;  Hu,Kun;  Li,Xiao-Nian;  Yang,Xing-Zhi;  Sun,Han-Dong;  Puno,Pema-Tenzin
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Isodon wardii  ent-Kauranoids  Cytotoxicity  Apoptosis  Cell cycle  
Isoxerophilins A and B, two diterpene heterodimers from Isodon xerophilus: structural elucidation and semisynthesis of isoxerophilin analogues 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2023, 卷号: 11, 期号: 1, 页码: 37-46
Authors:  Dai,Jia-Meng;  Yan,Bing-Chao;  Kong,Ling-Mei;  Hu,Kun;  Li,Xing-Ren;  Li,Xiao-Nian;  Sun,Han-Dong;  Li,Yan;  Puno,Pema-Tenzin
View  |  Adobe PDF(1181Kb)  |  Favorite  |  View/Download：50/10  |  Submit date：2024/05/09
ENT-KAURANE DITERPENOIDS  ABIETANE DITERPENOIDS  A-D  DIMERS  OXIDATION  CYCLOADDUCTS  ACTIVATION  LIGANDS  IBX  
Scalemic myrionsumamide A, tetracyclic skeleton alkaloids from Myrioneuron effusum 期刊论文
RSC ADVANCES, 2022, 卷号: 12, 期号: 43, 页码: 28147-28151
Authors:  Zhang, Jia-Hui;  Cao, Mingming;  Zhang, Yu;  Li, Xiao-Hui;  Gu, Yu-Cheng;  Li, Xiao-Nian;  Di, Ying-Tong;  Hao, Xiao-Jiang
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UNITS  
Pesimquinolones I-S, eleven new quinolone alkaloids produced by Penicillium simplicissimum and their inhibitory activity on NO production 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 104635
Authors:  Dai,Chong;  Li,Xiaoxin;  Zhang,Kailin;  Li,Xiao-Nian;  Wang,Wenjing;  Zang,Yi;  Chen,Xia;  Li,Qin;  Wei,Mengsha;  Chen,Chunmei;  Zhu,Hucheng;  Zhang,Yonghui
Favorite  |  View/Download：89/0  |  Submit date：2022/04/02
Penicillium simplicissimum  Quinolone alkaloids  inhibitory activity on NO production  
Unprecedented polycyclic polyprenylated acylphloroglucinols with anti-Alzheimer's activity from St. John's wort 期刊论文
CHEMICAL SCIENCE, 2021, 卷号: 12, 期号: 34, 页码: 11438-11446
Authors:  Guo,Yi;  Huang,Fang;  Sun,Weiguang;  Zhou,Yuan;  Chen,Chunmei;  Qi,Changxing;  Yang,Jing;  Li,Xiao-Nian;  Luo,Zengwei;  Zhu,Hucheng;  Wang,Xiaochuan;  Zhang,Yonghui
Favorite  |  View/Download：162/0  |  Submit date：2022/04/02
AMYLOID-BETA  NEUROFIBRILLARY DEGENERATION  HYPERFORIN  NEUROTOXICITY  PATHOGENESIS  INHIBITION  BACE1  DRUG  TAU