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Rubiginosin B selectively inhibits Treg cell differentiation and enhances anti-tumor immune responses by targeting calcineurin-NFAT signaling pathway 期刊论文
PHYTOMEDICINE, 2023, 卷号: 116, 页码: 154898
Authors:  Geng,Chang-An;  Chen,Feng-Yang;  Zheng,Jing-Bin;  Liao,Ping;  Li,Tian-Ze;  Zhang,Xue-Mei;  Chen,Xin;  Chen,Ji-Jun
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Rubiginosin B (RGB)  CD4(+)Foxp3(+) regulatory T cells (Tregs)  Calcineurin  Nuclear factor of activated T cells (NFAT)  Tumor microenvironment  Rhododendron brachypodum  REGULATORY T-CELLS  RHODODENDRON  IMMUNOSUPPRESSION  DERIVATIVES  INDUCTION  EXPANSION  RAPAMYCIN  
Discovery of Natural Potent HMG-CoA Reductase Degraders for Lowering Cholesterol 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023
Authors:  Su,Xiao-Zheng;  Zhang,Lin-Fei;  Hu,Kun;  An,Yang;  Zhang,Qiao-Peng;  Tang,Jian-Wei;  Yan,Bing-Chao;  Li,Xing-Ren;  Cai,Jie;  Li,Xiao-Nian;  Sun,Han-Dong;  Jiang,Shi-You;  Puno,Pema-Tenzin
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Enzymes  Meroterpenoids  Natural Products  Proteomics  Semisynthesis  STATIN  FUNGUS  RISK  ACID  
Artemeriopolides A-D, two types of sesquiterpenoid dimers with rare carbon skeletons from Artemisia eriopoda and their antihepatoma cytotoxicity 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2023, 卷号: 10, 期号: 11, 页码: 2635-2641
Authors:  He,Xiao-Feng;  Li,Qi-Hao;  Li,Tian-Ze;  Ma,Yun-Bao;  Dong,Wei;  Yang,Ke-Xin;  Geng,Chang-An;  Zhang,Hao-Wei;  Wang,Yuan;  Chen,Ji-Jun
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Characterization of two chimeric sesterterpene synthases from a fungal symbiont isolated from a sesterterpenoid-producing Lamiaceae plant Leucosceptrum canum 期刊论文
CHINESE CHEMICAL LETTERS, 2023, 卷号: 34, 期号: 1, 页码: 107469
Authors:  Li,Desen;  Yang,Minjie;  Mu,Rongfang;  Luo,Shihong;  Chen,Yuegui;  Li,Wenyuan;  Wang,An;  Guo,Kai;  Liu,Yan;  Li,Shenghong
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Sesterterpenoids  Chimeric sesterterpene synthases  Plant symbiotic fungi  Alternaria alternata  Leucosceptrum canum  Anti-adipogenic activity  GLANDULAR TRICHOMES  ALTERNARIA-ALTERNATA  HARBOR  
An ethnobotanical study of wild edible plants used by the Tibetan in the Rongjia River Valley, Tibet, China 期刊论文
JOURNAL OF ETHNOBIOLOGY AND ETHNOMEDICINE, 2023, 卷号: 19, 期号: 1, 页码: 49
Authors:  Wang,Jin;  Ding,Xiaoyong;  Guo,Chang-An;  Zhang,Xiong;  Feng,Haowen;  Yang,Huizhao;  Wang,Yuhua
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Tibetan  Wild edible plants  Ethnobotany  Traditional knowledge  Everest region  VEGETABLES  
Novel PORCN inhibitor WHN-88 targets Wnt/?-catenin pathway and prevents the growth of Wnt-driven cancers 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2023, 卷号: 945, 页码: 175628
Authors:  Yang,Qihong;  Qin,Tong;  An,Tao;  Wu,Hongna;  Xu,Gang;  Xiang,Jin;  Lei,Kangfan;  Zhang,Shaohua;  Xia,Jie;  Su,Guifeng;  Wang,Dan;  Xue,Minggao;  Kong,Lingmei;  Zhang,Wenxuan;  Wu,Song;  Li,Yan
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PORCN inhibitor  WHN-88  Palmitoylation  Wnt-driven cancers  SIGNALING PATHWAY  PORCUPINE  STEM  GENE  ACYLTRANSFERASE  MUTATIONS  POLARITY  PROTEIN  RNF43  MICE  
Traditional ecological knowledge-based calendar system for sustainable seasonal grazing in the Pamir Mountains 期刊论文
JOURNAL OF CLEANER PRODUCTION, 2023, 卷号: 414, 页码: 137756
Authors:  Yang,Huizhao;  Zhai,Deli;  Ranjitkar,Sailesh;  Zhong,Micai;  Guo,Chang'an;  Zhang,Xiong;  Yang,Jianwei;  Yang,Weikang;  Xu,Jianchu;  Wang,Yuhua
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Sustainable management  Indigenous seasonal grazing  Ecological calendar  Climate adaptation  Mountain ecosystem  CLIMATE-CHANGE ADAPTATION  SPRING PHENOLOGY  ASSESSMENTS  XINJIANG  INCREASE  SCIENCE  
Two new guaiane-type sesquiterpenes from Curcuma wenyujin 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2023
Authors:  Jiang,Xian-Jun;  Li,Yan;  Li,Xiang-Mei;  Wen,Shi-Zhen;  Yang,Sai-Lei;  Wei,Guo-Zhu;  Geng,Chang-An
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Curcuma wenyujin  guaiane-type sesquiterpenes  wenyujinolide A  wenyujinolide B  
Synthesis and biological evaluation of (20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol derivatives as alpha-glucosidase and PTP1B inhibitors 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 2, 页码: 350-367
Authors:  Yang, Xiao-Tong;  Li, Tian-Ze;  Geng, Chang-An;  Liu, Pei;  Chen, Ji-Jun
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(20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol  alpha-glucosidase inhibitors  PTP1B inhibitors  Enzyme kinetics  TYROSINE-PHOSPHATASE 1B  DIABETES-MELLITUS  EPIDEMIOLOGY  
Nakamurella leprariae sp. nov., isolated from a lichen sample 期刊论文
ARCHIVES OF MICROBIOLOGY, 2022, 卷号: 204, 期号: 1, 页码: 19
Authors:  An, De-Feng;  Yang, Shao-Juan;  Jiang, Long-Qian;  Wang, Xin-Yu;  Huang, Xiao-Yu;  Lang, Lei;  Chen, Xue-Mei;  Fan, Ming-Qun;  Li, Gui-Ding;  Jiang, Ming-Guo;  Wang, Li-Song;  Jiang, Cheng-Lin;  Jiang, Yi
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