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Termipaniculatones A-F, chalcone-flavonone heterodimers from Terminthia paniculata, and their protective effects on hyperuricemia and acute gouty arthritis 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 164, 页码: 228-235
Authors:  Yang, Tong-Hua;  Yan, De-Xiu;  Huang, Xiao-Yan;  Hou, Bo;  Ma, Yun-Bao;  Peng, Hua;  Zhang, Xue-Mei;  Chen, Ji-Jun;  Geng, Chang-An
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Terminthia paniculata (Wall. ex G. Don) CY Wu & TL Ming  Anacardiaceae  Termipaniculatones A-F  Chalcone-flavonone heterodimers  Xanthine oxidase inhibitors  Anti-gout potency  
Pharmacokinetics and safety evaluation in healthy Chinese volunteers of alkaloids from leaf of Alstonia scholaris: A multiple doses phase I clinical trial 期刊论文
PHYTOMEDICINE, 2019, 卷号: 61, 页码: 13
Authors:  Li, Rui;  Zi, Ming-Jie;  Gou, Zhong-Ping;  Zhao, Yun-Li;  Zhang, Wan-Tong;  Lu, Fang;  Cao, Wei-Yi;  Zhao, Ying-Pan;  Li, Qing-Na;  Zhao, Yang;  Wang, Shu-Ge;  Gao, Hong-Yang;  Sun, Ming-Yue;  Luo, Xiao-Dong;  Xiong, Zhi-Li;  Gao, Rui
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Capsule of alkaloids from leaf of A. scholaris (CALAS)  Pharmacokinetics  Safety evaluation  Drug re-excitation research  
Polybenzyls from Gastrodia elata, their agonistic effects on melatonin receptors and structure-activity relationships 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3299-3306
Authors:  Chen, Si-Yue;  Geng, Chang-An;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Yang, Xiao-Tong;  Su, Li-Hua;  He, Xiao-Feng;  Li, Tian-Ze;  Deng, Zhen-Tao;  Gao, Zhen;  Zhang, Xue-Mei;  Chen, Ji-Jun
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Gastrodia elata  Polybenzyls  Melatonin receptors  Structure-activity relationships  Docking study  
Antidepressant potential of Uncaria rhynchophylla and its active flavanol, catechin, targeting melatonin receptors 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 232, 页码: 39-46
Authors:  Geng, Chang-An;  Yang, Tong-Hua;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Zhang, Xue-Mei;  Chen, Ji-Jun
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Uncaria rhynchophylla  Catechin  Melatonin receptors  Metabolites  Antidepressant activity  
Structural Revision of Macropodumine A and Structure of 2-Deoxymacropodumine A, Daphniphyllum Alkaloids with 11-Membered Macrolactone Rings 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2019, 卷号: 82, 期号: 3, 页码: 427-430
Authors:  Zhang, Jiahui;  Cao, Pei;  Ma, Yuanliang;  Fang, Xin;  Yang, Jing;  Zhang, Yu;  Chen, Duozhi;  Gu, Yucheng;  Di, Yingtong;  Hao, Xiaojiang
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儿茶素在制备治疗中枢神经系统疾病药物中的应用 专利
申请日期: 2018-10-12, 公开日期: 2018-12-04
Inventors:  陈纪军;  耿长安;  杨通华;  黄晓燕;  马云保;  张雪梅
Favorite  |  View/Download:45/0  |  Submit date:2019/08/14
Anti-hepatitis B virus effects of the traditional Chinese herb Arteinisia capillaris and its active enynes 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2018, 卷号: 224, 页码: 283-289
Authors:  Geng, Chang-An;  Yang, Tong-Hua;  Huang, Xiao-Yan;  Yang, Jing;  Ma, Yun-Bao;  Li, Tian-Ze;  Zhang, Xue-Mei;  Chen, Ji-Jun
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Artemisia capillaris  Enynes  Anti-HBV activity  Structure-activity relationships  
LC-MS guided isolation of gracilistones A and B, a pair of diastereomeric sesquiterpenoids with an unusual tetrahydrofuran-fused tricyclic skeleton from Acanthopanax gracilistylus and their potential anti-inflammatory activities 期刊论文
FITOTERAPIA, 2018, 卷号: 130, 页码: 265-271
Authors:  Xu, Hong-Bo;  Yang, Tong-Hua;  Xie, Pei;  Tang, Zhi-Shu;  Song, Xiao;  Xu, Huai-Li;  Li, Yan-Hong;  Zhang, Dong-Bo;  Liu, Yan-Ru;  Liang, Yan-Ni;  Zhang, Yu;  Liu, Shi-Jun;  Wei, Si-Min;  Sun, Chen;  Liu, Hong-Bo;  Deng, Chong;  Wang, Wei
Favorite  |  View/Download:119/0  |  Submit date:2018/12/03
Acanthopanax gracilistylus  Eudesmane-type sesquiterpenoid  LC-MS  Anti-inflammation  Anti-oxidant  Xanthine oxidase  
先花铃子香中化合物及其药物组合物和其在制药中的应用 专利
申请日期: 2018-08-31, 公开日期: 2018-12-21
Inventors:  陈纪军;  邓振涛;  耿长安;  杨通华;  张雪梅;  黄晓燕;  马云保;  李天泽
Favorite  |  View/Download:29/0  |  Submit date:2019/08/14
Synthesis and biological evaluation of magnolol derivatives as melatonergic receptor agonists with potential use in depression 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 156, 期号: 0, 页码: 381-393
Authors:  Yang, Tong-Hua;  Ma, Yun-Bao;  Geng, Chang-An;  Yan, De-Xiu;  Huang, Xiao-Yan;  Li, Tian-Ze;  Zhang, Xue-Mei;  Chen, Ji-Jun
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Depression  Magnolol Derivatives  Mt1/2 Receptors  Metabolites  Monoamine Neurotransmitter