Three new diterpenoids fromEuphorbia peplus
Chen,Yan-Ni; Lu,Qing-Yun; Li,Dong-Mei; Li,Ying-Yao; Pu,Xue-Xue; Li,Bo-Ting; Tang,Xiao-Han; Tang,Hong-Yu; Liu,Shuai; Yang,Lei; Zhang,Yu; Di,Ying-Tong; Fang,Xin; Hao,Xiao-Jiang
AbstractThree new diterpenoids (1-3) (two abietane type diterpenoids and a paralianone type diterpenoid), together with four known compounds (4-7) were isolated from the whole plants ofEuphorbia peplus. Their structures were elucidated through spectroscopic analysis and physicochemical characteristics. The cytotoxic activities of compounds1-7against five human tumour cell lines were evaluated, however, they were inactive at the concentration of 40 mu M. The compound3enhanced lysosomal biogenesis with Lyso Tracker staining intensity of 132.6%.
KeywordEuphorbiaceae Euphorbia peplus ent-abietane diterpenoids paralianone diterpenoids EUPHORBIA-PEPLUS STEMS
WOS IDWOS:000559848400001
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Affiliation1.Yunnan Univ Tradit Chinese Med, Kunming, Yunnan, Peoples R China
2.Shanghai Chenshan Bot Garden, Plant Sci Res Ctr, Shanghai Key Lab Plant Funct Genom & Resources, Shanghai, Shanghai, Peoples R China
3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, 132 Lanhei Rd, Kunming 650201, Yunnan, Peoples R China
4.Yunnan Univ, Kunming, Yunnan, Peoples R China
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GB/T 7714
Chen,Yan-Ni,Lu,Qing-Yun,Li,Dong-Mei,et al. Three new diterpenoids fromEuphorbia peplus[J]. NATURAL PRODUCT RESEARCH,2021,35(21):3901-3907.
APA Chen,Yan-Ni.,Lu,Qing-Yun.,Li,Dong-Mei.,Li,Ying-Yao.,Pu,Xue-Xue.,...&Hao,Xiao-Jiang.(2021).Three new diterpenoids fromEuphorbia peplus.NATURAL PRODUCT RESEARCH,35(21),3901-3907.
MLA Chen,Yan-Ni,et al."Three new diterpenoids fromEuphorbia peplus".NATURAL PRODUCT RESEARCH 35.21(2021):3901-3907.
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