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The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)1 期刊论文
出版物, 3111, 期号: 0, 页码: 1-42
Authors:  C Pergola;  J Gerstmeier;  B Monch;  B Çaliskan;  S Luderer;  C Weinige;  D Barz;  J Maczewsky;  S Pace;  A Rossi;  L Sautebin;  E Banoglu;  O Werz
Adobe PDF(1387Kb)  |  Favorite  |  View/Download:222/1  |  Submit date:2017/07/24
Metabolic profiling of tyrosine kinase inhibitor nintedanib using metabolomics 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020
Authors:  Zhou, Zi-Meng;  Wang, Yi-Kun;  Yan, Dong-Mei;  Fang, Jian-He;  Xiao, Xue-Rong;  Zhang, Ting;  Cheng, Yan;  Xu, Kang-Ping;  Li, Fei
View  |  Adobe PDF(4095Kb)  |  Favorite  |  View/Download:51/9  |  Submit date:2021/01/05
Effect of CYP3A4 on liver injury induced by triptolide 期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2020
Authors:  Xiao, Xuerong;  Zhang, Ting;  Huang, Jianfeng;  Zhao, Qi;  Li, Fei
View  |  Adobe PDF(4498Kb)  |  Favorite  |  View/Download:25/8  |  Submit date:2021/01/05
Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
Authors:  Yang, Xiao-Nan;  Wang, Yi-Kun;  Zhu, Xu;  Xiao, Xue-Rong;  Dai, Man-Yun;  Zhang, Ting;  Qu, Yan;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(9057Kb)  |  Favorite  |  View/Download:107/15  |  Submit date:2020/03/26
Role of Metabolic Activation in Elemicin-Induced Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 29, 页码: 8243-8252
Authors:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Zhu, Xu;  Xiao, Xue-Rong;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(3136Kb)  |  Favorite  |  View/Download:76/19  |  Submit date:2019/09/10
elemicin  l'-hydroxyelemicin  metabolic activation  cytotoxicity  
Impaired clearance of sunitinib leads to metabolic disorders and hepatotoxicity 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2162-2178
Authors:  Zhao, Qi;  Zhang, Ting;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Wang, Yan;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(3915Kb)  |  Favorite  |  View/Download:94/10  |  Submit date:2019/07/29
A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice 期刊论文
XENOBIOTICA, 2019, 卷号: 49, 期号: 6, 页码: 655-670
Authors:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Liang, Wei-Qing;  Xiao, Yao;  Zhao, Qi;  Xiao, Xue-Rong;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(1101Kb)  |  Favorite  |  View/Download:85/11  |  Submit date:2019/07/29
Pazopanib  hepatotoxicity  metabolomics  oxidative stress  ultra-performance liquid chromatography-electrospray ion source-quadrupole  time-of-flight mass spectrometer (UPLC-ESI-QTOFMS)  
Metabolic Activation of Myristicin and Its Role in Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 15, 页码: 4328-4336
Authors:  Zhu, Xu;  Wang, Yi-Kun;  Yang, Xiao-Nan;  Xiao, Xue-Rong;  Zhang, Ting;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Li, Fei
View  |  Adobe PDF(4316Kb)  |  Favorite  |  View/Download:127/17  |  Submit date:2019/05/24
myristicin  1 '-hydroxymyristicin  metabolic activation  metabolomics  
Metabolic profiling of the anti-tumor drug regorafenib in mice 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2018, 卷号: 159, 页码: 524-535
Authors:  Wang, Yi-Kun;  Xiao, Xue-Rong;  Xu, Kang-Ping;  Li, Fei
Favorite  |  View/Download:51/0  |  Submit date:2018/10/04
Regorafenib  Metabolomics  Multiple mass defect filters  Molecular docking  
无权访问的条目 演示报告
Authors:  彭惺蓉
Microsoft Powerpoint(9298Kb)  |  Favorite  |  View/Download:0/0  |  Submit date:2019/05/24