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Discovery of novel coffee diterpenoids with inhibitions on Ca(v)3.1 low voltage-gated Ca2+ channel 期刊论文
FOOD CHEMISTRY, 2022, 卷号: 376, 页码: 131923
Authors:  Hu,Guilin;  Dong,Ding;  Du,Shuzong;  Peng,Xingrong;  Wu,Mingkun;  Shi,Qiangqiang;  Hu,Kun;  Hong,Defu;  Wang,Xiaoyuan;  Zhou,Lin;  Nian,Yin;  Qiu,Minghua
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Coffea arabica L  Roasted coffee  Coffee diterpenoid  Cafestol  Kahweol  T-type Ca2+ channels  Ca(v)3.1 low voltage-gated Ca2+ channel  Ca(v)3.1 inhibitors  CALCIUM-CHANNELS  CAFESTOL  KAHWEOL  PHYSIOLOGY  ESTERS  NOMENCLATURE  PHARMACOLOGY  APOPTOSIS  FURANS  
Pesimquinolones I-S, eleven new quinolone alkaloids produced by Penicillium simplicissimum and their inhibitory activity on NO production 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 108, 页码: 104635
Authors:  Dai,Chong;  Li,Xiaoxin;  Zhang,Kailin;  Li,Xiao-Nian;  Wang,Wenjing;  Zang,Yi;  Chen,Xia;  Li,Qin;  Wei,Mengsha;  Chen,Chunmei;  Zhu,Hucheng;  Zhang,Yonghui
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Penicillium simplicissimum  Quinolone alkaloids  inhibitory activity on NO production  
Unprecedented polycyclic polyprenylated acylphloroglucinols with anti-Alzheimer's activity from St. John's wort 期刊论文
CHEMICAL SCIENCE, 2021, 卷号: 12, 期号: 34, 页码: 11438-11446
Authors:  Guo,Yi;  Huang,Fang;  Sun,Weiguang;  Zhou,Yuan;  Chen,Chunmei;  Qi,Changxing;  Yang,Jing;  Li,Xiao-Nian;  Luo,Zengwei;  Zhu,Hucheng;  Wang,Xiaochuan;  Zhang,Yonghui
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AMYLOID-BETA  NEUROFIBRILLARY DEGENERATION  HYPERFORIN  NEUROTOXICITY  PATHOGENESIS  INHIBITION  BACE1  DRUG  TAU  
Neuroprotective schinortriterpenoids from Schisandra neglecta collected in Medog County, Tibet, China 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 104785
Authors:  Wang,Bin;  Hu,Kun;  Li,Xiao-Nian;  Sun,Han-Dong;  Qin,Hong-Bo;  Puno,Pema-Tenzin
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Schisandra neglecta  16  17-secopreschisanartane-type  schinortriterpenoids  Schisdilactones K?U  Quantum chemical calculation  Neuroprotective activity  DIBENZOCYCLOOCTADIENE LIGNANS  NORTRITERPENOIDS  CHINENSIS  STEMS  7,8-SECOLIGNANS  TRITERPENOIDS  
Neuroprotective compounds from the resinous heartwood of Aquilaria sinensis 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 181, 页码: 112554
Authors:  He,Qian;  Hu,Dong-Bao;  Zhang,Lu;  Xia,Meng-Yuan;  Yan,Hui;  Li,Xiao-Nian;  Luo,Ji-Feng;  Wang,Yun-Song;  Yang,Jing-Hua;  Wang,Yue-Hu
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Aquilaria sinensis  Thymelaeaceae  Sesquiterpenoids  2-(2-Phenylethyl)chromones  Neuroprotective  
Introgression between Betula tianshanica and Betula microphylla and its implications for conservation 期刊论文
PLANTS PEOPLE PLANET, 2021, 卷号: 3, 期号: 4, 页码: 363-374
Authors:  Ding,Junyi;  Hua,Donglai;  Borrell,James S.;  Buggs,Richard J. A.;  Wang,Luwei;  Wang,Feifei;  Li,Zheng;  Wang,Nian
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Betula microphylla  birch  conservation  ecological niche modelling  genetic structure  hybridization  introgression  species record  MICROSATELLITE MARKERS  DWARF BIRCH  HYBRIDIZATION  EVOLUTION  FRAMEWORK  SPECIATION  DISCOVERY  PUBESCENS  TRANSPORT  SEQUENCE  
Schipropins A-J, structurally diverse triterpenoids from Schisandra propinqua 期刊论文
PHYTOCHEMISTRY, 2021, 卷号: 182, 页码: 112589
Authors:  Ma,Ren-Fen;  Hu,Kun;  Ding,Wen-Ping;  Wang,Bin;  He,Tao-Bin;  Li,Xiao-Nian;  Sun,Han-Dong;  Puno,Pema-Tenzin
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Schisandra propinqua  Lanostane-type triterpenoids  Cycloartane-type triterpenoids  Cytotoxicity  Anti-inflammation  NORTRITERPENOIDS  LIGNANS  SKELETON  
New ent-kaurane diterpenes from the roasted arabica coffee beans and molecular docking to alpha-glucosidase 期刊论文
FOOD CHEMISTRY, 2021, 卷号: 345, 页码: 128823
Authors:  Hu,GuiLin;  Peng,XingRong;  Dong,Ding;  Nian,Yin;  Gao,Ya;  Wang,XiaoYuan;  Hong,DeFu;  Qiu,MingHua
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Coffea arabica  Ent-kaurane diterpene  alpha-Glucosidase  Molecular docking  
Phenylhydrazone and Quinazoline Derivatives from the Cold-Seep-Derived Fungus Penicillium oxalicum 期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 1, 页码: 9
Authors:  Liu,Ya-Ping;  Fang,Sheng-Tao;  Shi,Zhen-Zhen;  Wang,Bin-Gui;  Li,Xiao-Nian;  Ji,Nai-Yun
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Penicillium oxalicum  deep sea  cold seep  phenylhydrazone  quinazoline  
Harpertrioate A, an A,B,D-seco-Limonoid with Promising Biological Activity against Alzheimer's Disease from Twigs of Harrisonia perforata (Blanco) Merr 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 2, 页码: 262-267
Authors:  Tang,Xiao-Han;  Luo,Rong-Can;  Ye,Mao-Sen;  Tang,Hong-Yu;  Ma,Yuan-Liang;  Chen,Yan-Ni;  Wang,Xin-Meng;  Lu,Qing-Yun;  Liu,Shuai;  Li,Xiao-Nian;  Yan,Ying;  Yang,Jing;  Ran,Xiao-Qian;  Fang,Xin;  Zhou,Yan;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang
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AMYLOID PRECURSOR PROTEIN  INSULIN-DEGRADING ENZYME  BETA-PROTEIN  GEMFIBROZIL  PREVENTION  SECRETASE  ADAM10  MEN