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The Protective Roles of PPAR alpha Activation in Triptolide-Induced Liver Injury 期刊论文
TOXICOLOGICAL SCIENCES, 2019, 卷号: 171, 期号: 1, 页码: 1-12
Authors:  Hu, Dan-Dan;  Zhao, Qi;  Cheng, Yan;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Qu, Yan;  Li, Xian;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(1740Kb)  |  Favorite  |  View/Download:11/0  |  Submit date:2020/03/26
liver injury  metabolomics  PPAR alpha  acylcarnitines  
Impaired clearance of sunitinib leads to metabolic disorders and hepatotoxicity 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2162-2178
Authors:  Zhao, Qi;  Zhang, Ting;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Wang, Yan;  Gonzalez, Frank J.;  Li, Fei
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Celastrol Protects From Cholestatic Liver Injury Through Modulation of SIRT1-FXR Signaling 期刊论文
MOLECULAR & CELLULAR PROTEOMICS, 2019, 卷号: 18, 期号: 3, 页码: 520-533
Authors:  Zhao, Qi;  Liu, Fang;  Cheng, Yan;  Xiao, Xue-Rong;  Hu, Dan-Dan;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(4782Kb)  |  Favorite  |  View/Download:35/4  |  Submit date:2019/07/29
Modulation of Lipid Metabolism by Celastrol 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 3, 页码: 1133-1144
Authors:  Zhang, Ting;  Zhao, Qi;  Xiao, Xuerong;  Yang, Rui;  Hu, Dandan;  Zhu, Xu;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(5774Kb)  |  Favorite  |  View/Download:122/0  |  Submit date:2019/04/15
celastrol  lipidomics  hyperlipidemia  LC-MS  
Basal PPAR alpha inhibits bile acid metabolism adaptation in chronic cholestatic model induced by alpha-naphthylisothiocyanate 期刊论文
TOXICOLOGY LETTERS, 2019, 卷号: 300, 页码: 31-39
Authors:  Hua, Huiying;  Dai, Manyun;  Luo, Yishuang;  Lin, Hante;  Xu, Gangming;  Hu, Xiaowei;  Xu, Liping;  Zhang, Haoyue;  Tang, Zhiyuan;  Chang, Liming;  Liu, Aiming;  Yang, Julin
View  |  Adobe PDF(3156Kb)  |  Favorite  |  View/Download:186/2  |  Submit date:2018/12/18
PPAR alpha  FXR pathway  Alpha-naphthylisothiocyanate  Chronic cholestasis  
PPAR alpha Mediates the Hepatoprotective Effects of Nutmeg 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2018, 卷号: 17, 期号: 5, 页码: 1887-1897
Authors:  Yang, Xiao-Nan;  Liu, Xue-Mei;  Fang, Jian-He;  Zhu, Xu;  Yang, Xiu-Wei;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Gonzalez, Frank J.;  Li, Fei
View  |  Adobe PDF(2643Kb)  |  Favorite  |  View/Download:125/20  |  Submit date:2018/07/02
Nutmeg  Hepatoprotective Activity  Metabolomics  Myrislignan  Ppar Alpha  
胆汁淤积性肝损伤的代谢组学研究 学位论文
硕士, 2018
Authors:  杨锐
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PPAR alpha activation protects against cholestatic liver injury 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 9967
Authors:  Zhao, Qi;  Yang, Rui;  Wang, Jing;  Hu, Dan-Dan;  Li, Fei
View  |  Adobe PDF(7693Kb)  |  Favorite  |  View/Download:110/14  |  Submit date:2017/10/23
Primary Biliary-cirrhosis  Bile-acid Homeostasis  Receptor-alpha  Ursodeoxycholic Acid  Cholesterol 7-alpha-hydroxylase  Beta-oxidation  Fenofibrate  Therapy  Mice  Hepatotoxicity  
Cycloartane triterpenoids from the stems of Schisandra glaucescens and their bioactivity 期刊论文
FITOTERAPIA, 2012, 卷号: 83, 期号: 5, 页码: 926-931
Authors:  Zou, Juan;  Jiang, Jing;  Diao, Yan-Yan;  Yang, Li-Bin;  Huang, Jin;  Li, Hong-Lin;  Du, Xue;  Xiao, Wei-Lie;  Pu, Jian-Xin;  Sun, Han-Dong
Adobe PDF(813Kb)  |  Favorite  |  View/Download:180/42  |  Submit date:2014/04/02
Schisandra Glaucescens  Schisandraceae  Cycloartane Triterpenoid  Fxr Agonistic And antAgonistic Effects  
Biochemical, haematological and histopathological studies of extract of Ageratum conyzoides L. in Sprague Dawley rats 期刊论文
JOURNAL OF MEDICINAL PLANTS RESEARCH, 2010, 卷号: 4, 期号: 21, 页码: 2264-2272
Authors:  Adebayo, Abiodun Humphrey;  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Ji, Chang-Jiu;  He, Wen-Jun;  Xu, Jun-Ju;  Zhang, Yu-Mei;  Akindahunsi, Afolabi Akintunde;  Kela, Roseline;  Tan, Ning-Hua
Adobe PDF(584Kb)  |  Favorite  |  View/Download:204/54  |  Submit date:2012/03/21
Ageratum Conyzoides  Asteraceae  Liver Markers  Histopathological Study  Toxicological Study