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Metabolomics reveals the role of PPAR alpha in Tripterygium Wilfordii-induced liver injury 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2022, 卷号: 289, 页码: 16
Authors:  Dai, Manyun;  Peng, Wan;  Zhang, Ting;  Zhao, Qi;  Ma, Xiaofang;  Cheng, Yan;  Wang, Chunyan;  Li, Fei
Favorite  |  View/Download:32/0  |  Submit date:2022/07/15
Tripterygium wilfordii  Liver injury  PPAR alpha  IL6-STAT3  Metabolomics  
Triterpenoids from functional mushroom Ganoderma resinaceum and the novel role of Resinacein S in enhancing the activity of brown/beige adipocytes 期刊论文
FOOD RESEARCH INTERNATIONAL, 2020
Authors:  Huang, Yanjie;  Wei, Gang;  Peng, Xingrong;  Hu, Guilin;  Su, Haiguo;  Liu, Junli;  Chen, Xia;  Qiu, Minghua
Adobe PDF(2431Kb)  |  Favorite  |  View/Download:32/4  |  Submit date:2021/01/05
Celastrol ameliorates acute liver injury through modulation of PPAR alpha 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2020
Authors:  Zhao, Qi;  Tang, Ping;  Zhang, Ting;  Huang, Jian-Feng;  Xiao, Xue-Rong;  Zhu, Wei-Feng;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(6195Kb)  |  Favorite  |  View/Download:30/7  |  Submit date:2021/01/05
Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
Authors:  Yang, Xiao-Nan;  Wang, Yi-Kun;  Zhu, Xu;  Xiao, Xue-Rong;  Dai, Man-Yun;  Zhang, Ting;  Qu, Yan;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(9057Kb)  |  Favorite  |  View/Download:107/15  |  Submit date:2020/03/26
The Protective Roles of PPAR alpha Activation in Triptolide-Induced Liver Injury 期刊论文
TOXICOLOGICAL SCIENCES, 2019, 卷号: 171, 期号: 1, 页码: 1-12
Authors:  Hu, Dan-Dan;  Zhao, Qi;  Cheng, Yan;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Qu, Yan;  Li, Xian;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(1740Kb)  |  Favorite  |  View/Download:100/5  |  Submit date:2020/03/26
liver injury  metabolomics  PPAR alpha  acylcarnitines  
Impaired clearance of sunitinib leads to metabolic disorders and hepatotoxicity 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2162-2178
Authors:  Zhao, Qi;  Zhang, Ting;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Wang, Yan;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(3915Kb)  |  Favorite  |  View/Download:94/10  |  Submit date:2019/07/29
Celastrol Protects From Cholestatic Liver Injury Through Modulation of SIRT1-FXR Signaling 期刊论文
MOLECULAR & CELLULAR PROTEOMICS, 2019, 卷号: 18, 期号: 3, 页码: 520-533
Authors:  Zhao, Qi;  Liu, Fang;  Cheng, Yan;  Xiao, Xue-Rong;  Hu, Dan-Dan;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(4782Kb)  |  Favorite  |  View/Download:72/14  |  Submit date:2019/07/29
A phytochemical investigation of Stemona parviflora roots reveals several compounds with nematocidal activity 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 159, 页码: 208-215
Authors:  Huang, Sheng-Zhuo;  Kong, Fan-Dong;  Chen, Gao;  Cai, Xiang-Hai;  Zhou, Li-Man;  Ma, Qing-Yun;  Wang, Qi;  Mei, Wen-Li;  Dai, Hao-Fu;  Zhao, You-Xing
Adobe PDF(614Kb)  |  Favorite  |  View/Download:184/17  |  Submit date:2019/03/25
Stemona parviflora  Stemonaceae  Phenanthrene  Stilbene  Nematocidal activity  
Modulation of Lipid Metabolism by Celastrol 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2019, 卷号: 18, 期号: 3, 页码: 1133-1144
Authors:  Zhang, Ting;  Zhao, Qi;  Xiao, Xuerong;  Yang, Rui;  Hu, Dandan;  Zhu, Xu;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(5774Kb)  |  Favorite  |  View/Download:157/8  |  Submit date:2019/04/15
celastrol  lipidomics  hyperlipidemia  LC-MS  
Basal PPAR alpha inhibits bile acid metabolism adaptation in chronic cholestatic model induced by alpha-naphthylisothiocyanate 期刊论文
TOXICOLOGY LETTERS, 2019, 卷号: 300, 页码: 31-39
Authors:  Hua, Huiying;  Dai, Manyun;  Luo, Yishuang;  Lin, Hante;  Xu, Gangming;  Hu, Xiaowei;  Xu, Liping;  Zhang, Haoyue;  Tang, Zhiyuan;  Chang, Liming;  Liu, Aiming;  Yang, Julin
Adobe PDF(3156Kb)  |  Favorite  |  View/Download:211/7  |  Submit date:2018/12/18
PPAR alpha  FXR pathway  Alpha-naphthylisothiocyanate  Chronic cholestasis