KIB OpenIR
O-Alkylazoxymycins A-F, Naturally Occurring Azoxy-Aromatic Compounds from Streptomyces sp. Py50
He,Xin; Peng,Guoqing; Luo,Jianying; Huang,Jian-Ping; Yang,Jing; Yan,Yijun; Gu,Yu-Cheng; Wang,Li; Huang,Sheng-Xiong
2023
Source PublicationJOURNAL OF NATURAL PRODUCTS
ISSN1520-6025
AbstractSix new azoxy-aromatic compounds (o-alkylazoxymy-cins A-F, 1-6) and two new nitrogen-bearing phenylvaleric/ phenylheptanoic acid derivatives (o-alkylphemycins A and B, 7 and 8) were isolated from Streptomyces sp. Py50. Their structures were elucidated based on HRESIMS, NMR, UV spectroscopic analyses, and X-ray crystallographic data. O-Alkylazoxymycins A-F (1-6) are the first natural examples of azoxy compounds with the azoxy bond attached to the ortho-position of the phenylheptanoic acid or phenylvaleric acid moiety. Compounds 1, 5, and 6 were active against Epidermophyton floccosum with MIC50 values ranging from 10.1 to 51.2 mu M. A plausible biosynthetic pathway of 2 and 3 was proposed.
KeywordISOMERIZATION AZOXIDES
Subject AreaPlant Sciences ; Pharmacology & Pharmacy
DOI10.1021/acs.jnatprod.2c00892
Indexed BySCI
WOS IDWOS:000918831800001
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/75294
Collection中国科学院昆明植物研究所
Recommended Citation
GB/T 7714
He,Xin,Peng,Guoqing,Luo,Jianying,et al. O-Alkylazoxymycins A-F, Naturally Occurring Azoxy-Aromatic Compounds from Streptomyces sp. Py50[J]. JOURNAL OF NATURAL PRODUCTS,2023.
APA He,Xin.,Peng,Guoqing.,Luo,Jianying.,Huang,Jian-Ping.,Yang,Jing.,...&Huang,Sheng-Xiong.(2023).O-Alkylazoxymycins A-F, Naturally Occurring Azoxy-Aromatic Compounds from Streptomyces sp. Py50.JOURNAL OF NATURAL PRODUCTS.
MLA He,Xin,et al."O-Alkylazoxymycins A-F, Naturally Occurring Azoxy-Aromatic Compounds from Streptomyces sp. Py50".JOURNAL OF NATURAL PRODUCTS (2023).
Files in This Item: Download All
File Name/Size DocType Version Access License
10.1021_acs.jnatprod(1709KB)期刊论文出版稿开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[He,Xin]'s Articles
[Peng,Guoqing]'s Articles
[Luo,Jianying]'s Articles
Baidu academic
Similar articles in Baidu academic
[He,Xin]'s Articles
[Peng,Guoqing]'s Articles
[Luo,Jianying]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[He,Xin]'s Articles
[Peng,Guoqing]'s Articles
[Luo,Jianying]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: 10.1021_acs.jnatprod.2c00892.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.