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Chemical constituents from the aerial parts of Rubia cordifolia L. with their NO inhibitory activity | |
Zhang,Hong; Fang,Wen-Tao; Li,Yan![]() | |
2023 | |
发表期刊 | NATURAL PRODUCT RESEARCH
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ISSN | 1478-6427 |
摘要 | A new naphthoquinone derivative (1) together with twenty-three known compounds (2-24), were isolated from the aerial parts of Rubia cordifolia L. Their structures were elucidated on the basis of NMR and HR-ESIMS data. Compounds 1-13 were assessed for their inhibitory effects on NO production in LPS-stimulated RAW 264.7 macrophage cells. Compounds 2-6 exhibited significant inhibitory activities with IC50 values of 21.37, 13.81, 24.56, 20.32, and 30.08 mu mol center dot L-1, respectively. |
关键词 | Rubiaceae Rubia cordifolia L naphthoquinone derivative flavonoids NO inhibitory activity NAPHTHOHYDROQUINONE DIMERS SECONDARY METABOLITES IDENTIFICATION ANTHRAQUINONES PURIFICATION DERIVATIVES FLAVONOIDS |
学科领域 | Chemistry ; Pharmacology & Pharmacy |
DOI | 10.1080/14786419.2023.2192491 |
收录类别 | SCI |
WOS记录号 | WOS:000955344200001 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/75602 |
专题 | 中国科学院昆明植物研究所 |
推荐引用方式 GB/T 7714 | Zhang,Hong,Fang,Wen-Tao,Li,Yan,et al. Chemical constituents from the aerial parts of Rubia cordifolia L. with their NO inhibitory activity[J]. NATURAL PRODUCT RESEARCH,2023. |
APA | Zhang,Hong.,Fang,Wen-Tao.,Li,Yan.,Kong,Qing-Hua.,Fang,Cheng-Wu.,...&Liu,Shou-Jin.(2023).Chemical constituents from the aerial parts of Rubia cordifolia L. with their NO inhibitory activity.NATURAL PRODUCT RESEARCH. |
MLA | Zhang,Hong,et al."Chemical constituents from the aerial parts of Rubia cordifolia L. with their NO inhibitory activity".NATURAL PRODUCT RESEARCH (2023). |
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