Chemical constituents from the aerial parts of Rubia cordifolia L. with their NO inhibitory activity

doi:10.1080/14786419.2023.2192491

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	Chemical constituents from the aerial parts of Rubia cordifolia L. with their NO inhibitory activity
	Zhang,Hong; Fang,Wen-Tao; Li,Yan; Kong,Qing-Hua; Fang,Cheng-Wu; Luo,Han; Liu,Shou-Jin
	2023
发表期刊	NATURAL PRODUCT RESEARCH
ISSN	1478-6427
摘要	A new naphthoquinone derivative (1) together with twenty-three known compounds (2-24), were isolated from the aerial parts of Rubia cordifolia L. Their structures were elucidated on the basis of NMR and HR-ESIMS data. Compounds 1-13 were assessed for their inhibitory effects on NO production in LPS-stimulated RAW 264.7 macrophage cells. Compounds 2-6 exhibited significant inhibitory activities with IC50 values of 21.37, 13.81, 24.56, 20.32, and 30.08 mu mol center dot L-1, respectively.
关键词	Rubiaceae Rubia cordifolia L naphthoquinone derivative flavonoids NO inhibitory activity NAPHTHOHYDROQUINONE DIMERS SECONDARY METABOLITES IDENTIFICATION ANTHRAQUINONES PURIFICATION DERIVATIVES FLAVONOIDS
学科领域	Chemistry ; Pharmacology & Pharmacy
DOI	10.1080/14786419.2023.2192491
收录类别	SCI
WOS记录号	WOS:000955344200001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/75602
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Zhang,Hong,Fang,Wen-Tao,Li,Yan,et al. Chemical constituents from the aerial parts of Rubia cordifolia L. with their NO inhibitory activity[J]. NATURAL PRODUCT RESEARCH,2023.
APA	Zhang,Hong.,Fang,Wen-Tao.,Li,Yan.,Kong,Qing-Hua.,Fang,Cheng-Wu.,...&Liu,Shou-Jin.(2023).Chemical constituents from the aerial parts of Rubia cordifolia L. with their NO inhibitory activity.NATURAL PRODUCT RESEARCH.
MLA	Zhang,Hong,et al."Chemical constituents from the aerial parts of Rubia cordifolia L. with their NO inhibitory activity".NATURAL PRODUCT RESEARCH (2023).

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