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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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FG寡糖抗凝抗血栓作用的活性特点与机制
学位论文
: 中国科学院大学, 2022
Authors:
蔡英
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Submit date:2024/05/14
FG寡糖,内源性因子X酶,抗凝抗血栓活性特点,止血功能
FG oligosaccharides, Intrinsic tenase, The characteristics of anticoagulant and antithrombotic activity, Haemostatic function
分子模拟应用于岩藻糖化糖胺聚糖 3D 结构确定及其与内源 性因子 X 酶的相互作用模式考察
学位论文
, 2021
Authors:
陈鼎元
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Submit date:2023/11/02
Structural characterization and anticoagulant analysis of the novel branched fucosylated glycosaminoglycan from sea cucumber Holothuria nobilis
期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 269, 页码: 118290
Authors:
Li,Shanni
;
Zhong,Wei
;
Pan,Ying
;
Lin,Lisha
;
Cai,Ying
;
Mao,Hui
;
Zhang,Taocui
;
Li,Sujuan
;
Chen,Ru
;
Zhou,Lutan
;
Wang,Weili
;
Cui,Qinghua
;
Yin,Ronghua
;
Huang,Shengxiong
;
Zhao,Jinhua
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Submit date:2022/04/02
Disaccharide branch
Fucosylated glycosaminoglycan
Holothuria nobilis
Oligosaccharide
Anticoagulant
INTRINSIC TENASE COMPLEX
CHONDROITIN SULFATE
ACAUDINA-MOLPADIOIDEA
FACTOR XASE
HEPARIN
DEPOLYMERIZATION
OLIGOSACCHARIDES
POLYSACCHARIDES
DERIVATIVES
Neolignans and Norlignans from Insect Medicine Polyphaga plancyi and Their Biological Activities
期刊论文
Natural products and bioprospecting, 2021, 卷号: 11, 期号: 1, 页码: 51-62
Authors:
Zhu,Hong-Jie
;
Xu,Te
;
Yan,Yong-Ming
;
Tu,Zheng-Chao
;
Cheng,Yong-Xian
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Submit date:2022/04/02
A review on the relationship of mast cells and macrophages in breast cancer - Can herbs or natural products facilitate their anti-tumor effects?
期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 164, 页码: 105321
Authors:
Gou,Leilei
;
Yue,Grace Gar-Lee
;
Puno,Pema Tenzin
;
Lau,Clara Bik-San
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Submit date:2022/04/02
Breast cancer
Mast cell
Macrophage
Natural products
Herbs
Extracts
TUMOR-ASSOCIATED MACROPHAGES
NF-KAPPA-B
MEDIATED ALLERGIC REACTIONS
PRO-INFLAMMATORY CYTOKINES
ANTIINFLAMMATORY ACTIVITY
ATOPIC-DERMATITIS
UMBROSA ROOT
TNF-ALPHA
IN-VIVO
C-KIT
The Toxicology of Native Fucosylated Glycosaminoglycans and the Safety of Their Depolymerized Products as Anticoagulants
期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 9, 页码: 487
Authors:
Lin,Lisha
;
Li,Sujuan
;
Gao,Na
;
Wang,Weili
;
Zhang,Taocui
;
Yang,Lian
;
Yang,Xingzhi
;
Luo,Dan
;
Ji,Xu
;
Zhao,Jinhua
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Submit date:2022/04/02
fucosylated glycosaminoglycan
anticoagulant
platelet aggregation
contact activation
hypotension
pulmonary embolism
CHONDROITIN SULFATE
CONTACT SYSTEM
COMPLEMENT
COAGULATION
ACTIVATION
ACCUMULATION
INVOLVEMENT
DERIVATIVES
KALLIKREIN
THROMBOSIS
Pharmacokinetics and Pharmacodynamics of a Depolymerized Glycosaminoglycan from Holothuria fuscopunctata, a Novel Anticoagulant Candidate, in Rats by Bioanalytical Methods
期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 4, 页码: 212
Authors:
Liu,Shuang
;
Zhang,Taocui
;
Sun,Huifang
;
Lin,Lisha
;
Gao,Na
;
Wang,Weili
;
Li,Sujuan
;
Zhao,Jinhua
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Submit date:2022/04/02
pharmacokinetics
pharmacodynamics
anticoagulant
fucosylated glycosaminoglycan
dHG-5
method validation
High-molecular-weight fucosylated glycosaminoglycan induces human platelet aggregation depending on alpha(IIb)beta(3) and platelet secretion
期刊论文
PLATELETS, 2021, 卷号: 32, 期号: 7, 页码: 975-983
Authors:
Lin,Lisha
;
Yang,Lian
;
Chen,Jun
;
Zhou,Lutan
;
Li,Sujuan
;
Gao,Na
;
Zhao,Jinhua
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Submit date:2022/04/02
Aggregation
fucosylated glycosaminoglycan
human platelets
secretion
alpha(IIb beta 3)
DEPOLYMERIZED HOLOTHURIAN GLYCOSAMINOGLYCAN
INTRINSIC TENASE COMPLEX
INTEGRIN ALPHA(IIB)BETA(3)
ACTIVATION
AGGLUTINATION
RECEPTOR
ADP
INHIBITION
GENERATION
MECHANISM
Unveiling the Disaccharide-Branched Glycosaminoglycan and Anticoagulant Potential of Its Derivatives
期刊论文
BIOMACROMOLECULES, 2021, 卷号: 22, 期号: 3, 页码: 1244-1255
Authors:
Yin,Ronghua
;
Zhou,Lutan
;
Gao,Na
;
Lin,Lisha
;
Sun,Huifang
;
Chen,Dingyuan
;
Cai,Ying
;
Zuo,Zhili
;
Hu,Kaifeng
;
Huang,Shengxiong
;
Liu,Jikai
;
Zhao,Jinhua
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Submit date:2022/04/02
FUCOSYLATED CHONDROITIN SULFATE
DEPOLYMERIZED HOLOTHURIAN GLYCOSAMINOGLYCAN
INTRINSIC TENASE COMPLEX
SEA-CUCUMBER
FUCOSE BRANCHES
BODY-WALL
INDEPENDENT INHIBITION
POLYSACCHARIDE ACCOUNT
FACTOR XASE
HEPARIN
A regular fucan sulfate from Stichopus herrmanni and its peroxide depolymerization: Structure and anticoagulant activity
期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 256, 页码: 117513
Authors:
Li,Xiaomei
;
Li,Shanni
;
Liu,Jie
;
Lin,Lisha
;
Sun,Huifang
;
Yang,Wenjiao
;
Cai,Ying
;
Gao,Na
;
Zhou,Lutan
;
Qin,Hongbo
;
Yin,Ronghua
;
Zhao,Jinhua
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Submit date:2022/04/02
fucan sulfate
peroxide depolymerization
oligosaccharides
anti-thrombin activity
FUCOSYLATED CHONDROITIN SULFATE
FREE-RADICAL DEPOLYMERIZATION
PHYSICOCHEMICAL CHARACTERISTICS
REPEATING UNIT
BODY-WALL
SEA
FUCOIDAN
GLYCOSAMINOGLYCAN
POLYSACCHARIDES
HEPARIN